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Find 4 Star Hotels in Medical Center District, TX from $191
Check availability on Medical Center District 4 Star Hotels
Compare Medical Center District 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Riverwalk Plaza
Riverwalk Plaza
8.2 out of 10, Very Good, 3,658 reviews
The price is $119
$141 total
includes taxes & fees
Jun 9 - Jun 10
Canopy by Hilton San Antonio Riverwalk
Canopy by Hilton San Antonio Riverwalk
9.4 out of 10, Exceptional, 1,325 reviews
The price is $191
$230 total
includes taxes & fees
Jun 16 - Jun 17
JW Marriott San Antonio Hill Country Resort & Spa
JW Marriott San Antonio Hill Country Resort & Spa
8.8 out of 10, Excellent, 1,019 reviews
The price is $356
$472 total
includes taxes & fees
Jul 4 - Jul 5
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Hotel Contessa
Hotel Contessa
8.8 out of 10, Excellent, 2,777 reviews
The price is $190
$239 total
includes taxes & fees
Jun 17 - Jun 18
Hyatt Regency San Antonio Riverwalk
Hyatt Regency San Antonio Riverwalk
8.8 out of 10, Excellent, 1,631 reviews
The price is $195
$233 total
includes taxes & fees
Jun 15 - Jun 16
Hotel Gibbs Downtown Riverwalk
Hotel Gibbs Downtown Riverwalk
9.0 out of 10, Wonderful, 2,912 reviews
The price is $116
$136 total
includes taxes & fees
Jun 13 - Jun 14
Omni La Mansion del Rio
Omni La Mansion del Rio
9.2 out of 10, Wonderful, 2,182 reviews
The price is $197
$236 total
includes taxes & fees
Jun 23 - Jun 24
Hotel Valencia Riverwalk
Hotel Valencia Riverwalk
9.2 out of 10, Wonderful, 1,758 reviews
The price is $159
$193 total
includes taxes & fees
Jun 16 - Jun 17
Grand Hyatt San Antonio River Walk
Grand Hyatt San Antonio River Walk
8.8 out of 10, Excellent, 1,094 reviews
The price is $189
$227 total
includes taxes & fees
Jun 15 - Jun 16
The St. Anthony, A Luxury Collection Hotel, San Antonio
The St. Anthony, A Luxury Collection Hotel, San Antonio
9.0 out of 10, Wonderful, 1,009 reviews
The price is $183
$217 total
includes taxes & fees
Jun 9 - Jun 10
The Westin San Antonio North
The Westin San Antonio North
8.4 out of 10, Very Good, 1,011 reviews
The price is $111
$131 total
includes taxes & fees
Jul 1 - Jul 2
La Cantera Resort & Spa
La Cantera Resort & Spa
8.8 out of 10, Excellent, 1,070 reviews
The price is $333
$435 total
includes taxes & fees
Jul 1 - Jul 2
Element San Antonio Riverwalk
Element San Antonio Riverwalk
8.8 out of 10, Excellent, 275 reviews
The price is $122
$144 total
includes taxes & fees
Jun 16 - Jun 17
AC Hotel by Marriott San Antonio Riverwalk
AC Hotel by Marriott San Antonio Riverwalk
8.4 out of 10, Very Good, 263 reviews
The price is $118
$140 total
includes taxes & fees
Jun 16 - Jun 17
Plaza San Antonio Hotel & Spa, Autograph Collection
Plaza San Antonio Hotel & Spa, Autograph Collection
9.2 out of 10, Wonderful, 95 reviews
The price is $167
$200 total
includes taxes & fees
Jul 7 - Jul 8
The Westin Riverwalk, San Antonio
The Westin Riverwalk, San Antonio
8.6 out of 10, Excellent, 1,049 reviews
The price is $175
$208 total
includes taxes & fees
Jun 30 - Jul 1
Hyatt Regency Hill Country Resort & Spa
Hyatt Regency Hill Country Resort & Spa
8.8 out of 10, Excellent, 1,006 reviews
The price is $224
$313 total
includes taxes & fees
Jun 24 - Jun 25
Hilton Palacio Del Rio
Hilton Palacio Del Rio
8.8 out of 10, Excellent, 1,583 reviews
The price is $165
$195 total
includes taxes & fees
Jun 23 - Jun 24
Marriott San Antonio Airport
Marriott San Antonio Airport
8.2 out of 10, Very Good, 1,004 reviews
The price is $118
$139 total
includes taxes & fees
Jul 5 - Jul 6
Hilton San Antonio Hill Country
Hilton San Antonio Hill Country
8.0 out of 10, Very Good, 1,103 reviews
The price is $135
$160 total
includes taxes & fees
Jun 16 - Jun 17
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Medical Center District.
Thompson San Antonio - Riverwalk, by Hyatt
115 Lexington Avenue, San Antonio, TX
The price is $191 per night from Jun 23 to Jun 24
$191
$230 total
includes taxes & fees
Jun 23 - Jun 24
8.8/10 Excellent! (509 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Recent reviews of Medical Center District hotelsExpedia verified reviews
5/5 Excellent
"Great location and beautiful hotel. In walking distance to La Villita Historic Village and even the mall (and I’m pregnant)! Great breakfast and bar food in the hotel and in walking distance to some of the best restaurants in the city. "
A verified traveler stayed at Hotel Contessa
Posted 2 days ago
Medical Center District Hotels by Star Rating
Hotels in Medical Center District Neighborhoods
Stay near popular Medical Center District attractions
- USAA Corporate Office Headquarters
- South Texas Medical Center
- CHRISTUS Santa Rosa Hospital - Medical Center
- University of Texas Health and Science Center at San Antonio
- Oak Hills Country Club
- The San Antonio Art Institute
- Six Flags Fiesta Texas
- Lackland Air Force Base
- Alamo
- Alamodome
- Henry B. González Convention Center
- San Antonio Zoo and Aquarium
- Frost Bank Center
- River Walk
- The Shops of La Cantera
- San Antonio River
- The Rim Shopping Center
Explore more hotels
- Hotel Contessa
- Crockett Hotel
- Hotel Gibbs Downtown Riverwalk
- Hotel Valencia Riverwalk
- Canopy by Hilton San Antonio Riverwalk
- Drury Plaza Hotel San Antonio Riverwalk
- Hyatt Regency San Antonio Riverwalk
- Omni La Mansion del Rio
- La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
- JW Marriott San Antonio Hill Country Resort & Spa
- Drury Plaza Hotel San Antonio Airport
- Grand Hyatt San Antonio River Walk
- La Quinta Inn by Wyndham San Antonio I-35 N at Toepperwein
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- Homewood Suites by Hilton San Antonio Riverwalk/Downtown
- Hampton Inn & Suites San Antonio Northwest/Medical Center
- The Gunter Hotel San Antonio Riverwalk
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- The Westin San Antonio North
- La Cantera Resort & Spa
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