Find spa resorts & hotels in Midtown, St. Louis from $191

Start date: Check-in selected.
To Date
End date: Check-out

Check availability on Midtown Resorts & Hotels with Spas

This weekend
Next weekend

Top Midtown Resorts & Hotels with Spas

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1393)
"Wonderful stay! "
$163 nightly
The price is $191
Oct 1 - Oct 2
Total with taxes and fees
21C Museum Hotel St Louis

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very Good, (1000)
"Beautiful hotel with friendly staff!"
$192 nightly
The price is $224
Oct 5 - Oct 6
Total with taxes and fees
Ameristar Casino Resort and Spa

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1004)
"Beautiful stay at the four seasons! "
$425 nightly
The price is $497
Oct 25 - Oct 26
Total with taxes and fees
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (550)
"Service is exceptional!!!"
$629 nightly
The price is $733
Oct 2 - Oct 3
Total with taxes and fees
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Midtown

Find out more about Midtown

Top Midtown attractions for a relaxing vacation

Midtown, a vibrant hub in the heart of New York City, offers a perfect blend of relaxation and excitement for travelers seeking spa hotels. Begin your rejuvenating journey with a visit to the renowned Spa at Mandarin Oriental, where you can indulge in luxurious treatments while enjoying breathtaking views of the Manhattan skyline. Just a short stroll away, the iconic Central Park invites you to unwind amidst nature, with its picturesque paths ideal for leisurely walks or family picnics. For those seeking a cultural fix, the Museum of Modern Art (MoMA) is right around the corner, featuring world-class art collections that inspire creativity and provide a serene escape from the bustling city. After a day of exploration, retreat to one of Midtown's upscale hotels, such as the Westin New York, where you can enjoy spacious rooms, top amenities, and a tranquil spa that offers massages and wellness treatments designed to pamper your senses. As night falls, savor a delightful dinner at a nearby Michelin-starred restaurant, setting the stage for a perfect end to your day in this dynamic neighborhood.

Top Midtown Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Midtown?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Spa hotels are a great way to break away from your routine and add a layer of luxury to your vacation.
What's there to see and do in Midtown?
When you're in Midtown, enjoy exploring the sights and attractions here including Chaifetz Arena, Washington Avenue Historic District, and Topgolf. If you have spare time during your trip, you might want to make a stop at Samuel Cupples House and Museum of Contemporary Religious Art.
What is a Midtown spa hotel?
Spa hotels in Midtown feature on-site spas offering services like facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

Explore a world of travel with Expedia

Explore a world of travel with Expedia