Sikeston Vacations from $170
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Your Sikeston Vacation
There's tons to like about Sikeston, from its rich history to its rural countryside. When you're ready to say hi to this captivating city, our Sikeston vacation packages will be perfect for you. Fill your spare time with visits to Sikeston Depot Museum, The Book Bug and Central Park, some of the top attractions you just have to see during your trip to Sikeston. That dream Sikeston vacation is clicks away. Browse hotels, flights and more on Expedia for a getaway that's tailored to suit your travel style.
The Latest Sikeston vacation packages
Price found within the past 48 hours. Click for updated prices.
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Riverport
$170
per person
Oct 13 - Oct 16
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
7.6/10 Good! (1,012 reviews)
I like the spaciousness of the room, however, the room did smell musty and the beds were terrible. They need new mattresses in the worse way!!! I don't know if a lot of the hotels give Expedia customers, their lower grade rooms, but this room was terrible! I could not get to sleep each night because of the bedding, the mattress felt like I was sleeping on The rings of the mattress, it was absolutely terrible!! The breakfast is full of nothing but carbs. There's not any protein, but yogurt and boiled eggs. Everything else is just carbs. There was a lot of dirt and stains on the carpet in the stairwell, and only one elevator was working. If you are about economy and want to save money this is the hotel for you, but if you want class good sleep and not a musty smell in the room-Then this is not the hotel for you. Also the drain in the kitchen was disgusting and it smelled really bad too.
Reviewed on Sep 9, 2026
Remodeled and Inviting Free EV
$325
per person
Oct 23 - Oct 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9/10 Wonderful! (2 reviews)
It was nice to stay for a weekend but the neighborhood was nice I like the location where it wasn't too far from grocery stores food areas the only thing I was saying is it's nothing for the kids to do but overall I like it
Reviewed on Aug 7, 2026
Stay near popular Sikeston attractions
Central Park
7.2/10 (56 reviews)
Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.
Sikeston Depot Museum
7.6/10 (57 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
City of Miner Convention Center
This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.
Sikeston Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
$108 total
Sep 14 - Sep 15
Total with taxes and fees
9.6/10 Exceptional! (1,001 reviews)
"I wasn't impressed with this hotel, plus there are no good restaurants nearby. Not a place we'd stay again."
Reviewed on Sep 9, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$87 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
8.4/10 Very Good! (1,009 reviews)
"Bathroom was very dirty. Mattress should have been replaced long ago. There was a bullet hole in the outer layer of glass window. Windows very dirty. Breakfast was good."
Reviewed on Sep 7, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
$76 total
Sep 13 - Sep 14
Total with taxes and fees
7.2/10 Good! (1,000 reviews)
"The sheets in the bed had a blood stain on it. I told the lady at the front desk and she came and changed the sheets for me. The stopper in the sink for the bathroom was not functional. The couch in the office area had stains on it. The refrigerator freezer needed to be defrosted. It had a lot of ..."
Reviewed on Sep 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Sikeston Vacation Packages
Sikeston Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 16,400 |
Max Temp Winter | 45ºF |
Max Temp Summer | 85ºF |
Top Sights | Sikeston Depot Museum, Central Park and The Book Bug |
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Frequently asked questions
How much does a Sikeston vacation package cost?
You'll find cheap prices from $170 on Expedia for your Sikeston getaway. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Sikeston costs.
What are the cheapest months to go to Sikeston?
If you're hoping to score a cheap Sikeston vacation package, consider planning a trip in November, December and January. You'll typically find lower rates on hotels and flights during these months — ideal for travelers wishing to save money.
How many days is enough for Sikeston?
Usually, a handful of days is great for a Sikeston vacation. With a well-planned itinerary, you can go to all the popular sights such as The Book Bug, as well as explore some hidden treasures along the way.
Is it worth booking a vacation package to Sikeston?
Sikeston offers everything you need for an unforgettable getaway. Get your Sikeston vacation off to a flying start by visiting major attractions like Sikeston Depot Museum.
How to find the best Sikeston package deals?
Use Expedia's filters to find some great Sikeston package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Sikeston package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Sikeston vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking stays and flights separately. Better still, you can tailor your Sikeston escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sikeston?
Enjoy incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Sikeston trip.
Does Expedia offer Book Now, Pay Later Sikeston vacation packages?
If you're like us, you love traveling the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Sikeston vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you see them.
Explore a world of travel with Expedia
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- Sikeston Depot Museum
- Qulin Vacations
- Hunter Valley Winery
- Riverfront Bridge Park
- The Heritage House
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- Central Park
- Hayti Pentecostal Holiness Church
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- Visit Sikeston
- Stoddard County Civil War Memorial Cemetery
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.