Sikeston Vacations from $619
Book a Hotel + Flight or Car together to unlock savings
Your Sikeston Vacation
There's tons to like about Sikeston, from its rich history to its rural countryside. When you're ready to say hi to this captivating city, our Sikeston vacation packages will be perfect for you. Fill your spare time with visits to Sikeston Depot Museum, The Book Bug and Central Park, some of the top attractions you just have to see during your trip to Sikeston. That dream Sikeston vacation is clicks away. Browse hotels, flights and more on Expedia for a getaway that's tailored to suit your travel style.
The Latest Sikeston vacation packages
Price found within the past 48 hours. Click for updated prices.
Crowne Plaza St. Louis Airport by IHG
$619
per person
Nov 3 - Nov 10
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
Everything was amazing but the tv you can only watch one channel . So I believe upgrade on the tv every will be great.
Reviewed on Sep 12, 2026
Residence Inn by Marriott St. Louis West County
$676
per person
Nov 3 - Nov 10
found 1 hour ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (266 reviews)
Ive stayed here before. Rooms are nice because they have a desk kitchen snd couch. Bed was not good. We stayed here because our ac went out. I called and confirmed pet friendly booked and paid for the room only to arrive and be told its $100 pet fee. Thats not fair or ok.
Reviewed on Sep 4, 2026
The Royal Sonesta Chase Park Plaza St. Louis
Central West End
$770
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,012 reviews)
The staff did an excellent job. The hotel’s pool is dreamy and lots of restaurants around the area.
Reviewed on Sep 16, 2026
Stay near popular Sikeston attractions
Central Park
7.2/10 (56 reviews)
Central Park offers a peaceful retreat with playgrounds and open spaces for Sikeston families. Bring a blanket for a relaxing picnic or watch children enjoy the recreational facilities.
Sikeston Depot Museum
7.6/10 (57 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
City of Miner Convention Center
This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.
Sikeston Hotel Deals
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
$108 total
Sep 27 - Sep 28
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
"Great stay and friendly, nice staff! Loved it!"
Reviewed on Sep 15, 2026
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
$76 total
Sep 20 - Sep 21
Total with taxes and fees
7.2/10 Good! (1,001 reviews)
"Good place!"
Reviewed on Sep 16, 2026
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$87 nightly
$99 total
Sep 20 - Sep 21
Total with taxes and fees
8.4/10 Very Good! (1,004 reviews)
"Room were clean, staff was very courteous and helpful."
Reviewed on Sep 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Sikeston Vacation Packages
Sikeston Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 16,400 |
Max Temp Winter | 45ºF |
Max Temp Summer | 85ºF |
Top Sights | Sikeston Depot Museum, Central Park and The Book Bug |
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Frequently asked questions
How much does a Sikeston vacation package cost?
You'll find cheap prices from $619 on Expedia for your Sikeston getaway. However, a range of factors like the season, length of stay and your choice of hotel will determine how much your vacation to Sikeston costs.
What are the cheapest months to go to Sikeston?
If you're hoping to score a cheap Sikeston vacation package, consider planning a trip in November, December and January. You'll typically find lower rates on hotels and flights during these months — ideal for travelers wishing to save money.
How many days is enough for Sikeston?
Usually, a handful of days is great for a Sikeston vacation. With a well-planned itinerary, you can go to all the popular sights such as The Book Bug, as well as explore some hidden treasures along the way.
Is it worth booking a vacation package to Sikeston?
Sikeston offers everything you need for an unforgettable getaway. Get your Sikeston vacation off to a flying start by visiting major attractions like Sikeston Depot Museum.
How to find the best Sikeston package deals?
Use Expedia's filters to find some great Sikeston package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or look for Sikeston package deals in the off-season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your vacation package as soon as possible.
Is it cheaper to book a Sikeston vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking stays and flights separately. Better still, you can tailor your Sikeston escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sikeston?
Enjoy incredible bargains by booking your flights in advance with Expedia. If spontaneity is more your thing, snap up one of our last-minute deals for a spur-of-the-moment Sikeston trip.
Does Expedia offer Book Now, Pay Later Sikeston vacation packages?
If you're like us, you love traveling the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Sikeston vacation over 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure great vacation packages with payment plans as soon as you see them.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.