
Popular airlines from Myrtle Beach Intl. Airport (MYR) to Harrisburg Intl. Airport (MDT)
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Plan, book, fly with confidence
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Cheap Flights from Myrtle Beach to Harrisburg (MYR-MDT)
Prices were available within the past 7 days and start at $130 for one-way flights and $251 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Myrtle Beach (MYR) to Harrisburg (MDT)
May is typically the cheapest month to fly
Graph displaying average flight prices per month
Alternative airports near Harrisburg
Prices were available within the past 7 days. Prices and availability are subject to change.
Origin airport | Myrtle Beach Intl. |
Destination airport | Harrisburg Intl. |
Airlines serving | American Airlines, Delta, United |
Roundtrip price | $250 |
Distance | 465 mi |
Average flight time | 1 hour 32 mins |
Myrtle Beach to Harrisburg Flights
The cheapest times to fly from Myrtle Beach to Harrisburg
On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Harrisburg are during the month of September. You can find some of the cheapest flights from Myrtle Beach to Harrisburg with Expedia's search tool and vast selection of airlines.
The best time to book a flight from Myrtle Beach to Harrisburg
Sunday is one of the best days to book for cheap flights from Myrtle Beach to Harrisburg: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.
How to find cheap round-trip tickets from Myrtle Beach to Harrisburg
Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Harrisburg in 2025. You can also book with separate airlines for your outbound and return journeys, from $130 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.
Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Harrisburg flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.
You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Harrisburg airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.
*Terms apply.
Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.
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Top Routes from Myrtle Beach
- Myrtle Beach to Chicago (MYR - ORD)
- Myrtle Beach to Newark Liberty Intl. Airport (MYR - EWR)
- Myrtle Beach to Miami (MYR - MIA)
- Myrtle Beach to Tampa (MYR - TPA)
- Myrtle Beach to Detroit (MYR - DTW)
- Myrtle Beach to New York (MYR - LGA)
- Myrtle Beach to Fort Lauderdale (MYR - FLL)
- Myrtle Beach to Boston (MYR - BOS)
- Myrtle Beach to Hartford (MYR - BDL)
- Myrtle Beach to New York (MYR - JFK)
- Myrtle Beach to New Orleans (MYR - MSY)
- Myrtle Beach to Nashville (MYR - BNA)
Top Routes to Harrisburg
- Chicago to Harrisburg (ORD - MDT)
- Phoenix to Harrisburg (PHX - MDT)
- Chicago to Harrisburg (MDW - MDT)
- San Diego to Harrisburg (SAN - MDT)
- Los Angeles to Harrisburg (LAX - MDT)
- Boston to Harrisburg (BOS - MDT)
- Orange County to Harrisburg (SNA - MDT)
- Charlotte to Harrisburg (CLT - MDT)
- Minneapolis to Harrisburg (MSP - MDT)
- Denver to Harrisburg (DEN - MDT)
- Sacramento to Harrisburg (SMF - MDT)
- Springfield to Harrisburg (SPI - MDT)
Top Routes from Myrtle Beach
- Spirit Airlines Myrtle Beach to Chicago
- Spirit Airlines Myrtle Beach to Newark Liberty Intl. Airport
- Delta Myrtle Beach to Miami
- Spirit Airlines Myrtle Beach to Tampa
- Spirit Airlines Myrtle Beach to Detroit
- Spirit Airlines Myrtle Beach to New York
- Spirit Airlines Myrtle Beach to Fort Lauderdale
- Spirit Airlines Myrtle Beach to Boston
- American Airlines Myrtle Beach to New York
- Spirit Airlines Myrtle Beach to New Orleans
Top Routes to Harrisburg
- American Airlines Chicago to Harrisburg
- American Airlines Phoenix to Harrisburg
- American Airlines San Diego to Harrisburg
- Delta Los Angeles to Harrisburg
- American Airlines Boston to Harrisburg
- American Airlines Charlotte to Harrisburg
- American Airlines Minneapolis to Harrisburg
- United Denver to Harrisburg
- American Airlines Sacramento to Harrisburg
- Alaska Airlines Seattle to Harrisburg
Top Flight Destinations
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Harrisburg
Lancaster
Nearby Airports
- Grand Strand Airport (CRE)
- Florence Regional Airport (FLO)
- Wilmington Intl. Airport (ILM)
- Charleston Intl. Airport (CHS)
- Fayetteville Regional Airport (FAY)
- Albert J. Ellis Airport (OAJ)
- Columbia Metropolitan Airport (CAE)
- Hilton Head Island Airport (HHH)
- Coastal Carolina Regional Airport (EWN)
- Raleigh - Durham Intl. Airport (RDU)
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