
Find 2 Star Hotels in East Prairie, MO from $60
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Our top choices for East Prairie 2-star hotels

1. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham Sikeston
2. Hampton Inn Sikeston
Hampton Inn Sikeston
3. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner Area
4. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55
5. Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of America
6. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-Sikeston
7. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHG
8. Quality Inn Union City US 51
Quality Inn Union City US 51
9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
10. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MO
11. New Orleans Inn Portageville
New Orleans Inn Portageville
12. Reelfoot Lake Inn
Reelfoot Lake Inn
13. Hampton Inn Union City
Hampton Inn Union City
14. Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHG
15. Super 8 By Wyndham Marston
Super 8 By Wyndham Marston
16. Country Yard Inn and Suite
Country Yard Inn and Suite
17. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55
18. Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51
19. Quality Inn Cairo I-57
Quality Inn Cairo I-57
20. Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityExplore similar 3-star hotels

Drury Inn & Suites Sikeston, MO
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews

Super 8 By Wyndham Marston
Find out more about East Prairie
East Prairie Motel Guide
Planning a getaway with only a few bucks to spare? Expedia can help! With the inexpensive rates at the top motels in East Prairie, Missouri you can put together the vacation of your dreams without spending every penny of your yearly travel budget.
These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in East Prairie are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in East Prairie, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.
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Also, feel free to check out the motels near me page to find the cheapest deals on motels near your current location.
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