Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Downtown Cincinnati Luxury Hotels

See all 219 Hotels in Downtown Cincinnati
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

609 Walnut St, Cincinnati
4.5 out of 5.0
4.7 out of 5 (182 reviews)
From Dread to Delightwhen we arrived we found that they did not have a room with two beds. They offered a rollaway bed for an extra charge. The night staff was less than helpful and apparently a manager was unavailable. The room we were given was filthy. We found pasta sauce dried on the fabric of a chair, stains on ...
  Oct 8, 2017

$199

$199
Cincinnatian Hotel

Cincinnatian Hotel

601 Vine Street, Cincinnati
4.0 out of 5.0
4.2 out of 5 (466 reviews)
Fun night in CincinnatiThe Blink weekend started the night we visited this hotel. It was a perfect location for all the festivites, close enough to walk, but far enough away to avoid the crowds and noise later in the evening. The hotel itself is beautiful and represents old Cincinnati, rooms are spacious and I love the ...
  Oct 14, 2017

$132

$132
Millennium Cincinnati

Millennium Cincinnati

150 West 5th Street, Cincinnati
3.5 out of 5.0
3.2 out of 5 (1,889 reviews)
Nice hotel, good locationToo expensive for the amount of space. Double beds are smaller than other hotels. There was some sort of leak which made the carpet wet beside the bed next to the bathroom. Bathroom didn't appear clean. The restaurant inside the hotel was extremely expensive for a breakfast buffet, the food was cold ...
  Oct 17, 2017

$88

$88
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

35 W 5th St, Cincinnati
4.0 out of 5.0
4.3 out of 5 (349 reviews)
Friendly staff and helpful accommodations. However, the rugs need to be updated and appliances dusted and cleaned.
  Oct 16, 2017

$161

$161
Renaissance Cincinnati Downtown Hotel

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street, Cincinnati
3.5 out of 5.0
4.6 out of 5 (132 reviews)
Downtown CincyWe wanted a getaway downtown Cincy, close to the action and all that downtown has to offer. This was perfect.
  Sep 17, 2017

$170

$170
The Westin Cincinnati

The Westin Cincinnati

21 E 5th St, Cincinnati
4.0 out of 5.0
4.1 out of 5 (470 reviews)
Lovely roomThe room was comfortable, clean and spacious with a great view. The staff was great. The bathroom was cramped and would be hard to get around in if a guest has any physical difficulties. The tub didn't have grab bars useful for showering. I notice these things after traveling with an ill parent.
  Oct 15, 2017

$152

$152
Residence Inn by Marriott Cincinnati Downtown/The Phelps

Residence Inn by Marriott Cincinnati Downtown/The Phelps

506 East 4th Street, Cincinnati
3.0 out of 5.0
4.9 out of 5 (72 reviews)
Beautiful hotel downtown Cincinnati Lovely remodel, great location, top notch staff. 3 disappointments: 1. Roof bar closed on Sunday so unable to use. 2. Valet parking understood to be $20 appeared as $28 on Bill. 3. No pool.
  Oct 17, 2017

$170

$170
Map

Recently booked Luxury Hotels in Downtown Cincinnati

Millennium Cincinnati Hotel
3.5 out of 5.0
Last booking: 1 minute ago
Hyatt Regency Cincinnati
4.0 out of 5.0
Last booking: 1 hour ago
Cincinnatian Hotel
4.0 out of 5.0
Last booking: 3 hours ago
Quality Inn & Suites Cincinnati Downtown
2.0 out of 5.0
Last booking: 8 hours ago
21c Museum Hotel Cincinnati
4.5 out of 5.0
Last booking: 15 hours ago
The Westin Cincinnati
4.0 out of 5.0
Last booking: 18 hours ago
Residence Inn by Marriott Cincinnati Downtown/The Phelps
3.0 out of 5.0
Last booking: 22 hours ago
Renaissance Cincinnati Downtown Hotel
3.5 out of 5.0
Last booking: 24 hours ago
Symphony Hotel & Restaurant
3.5 out of 5.0
Last booking: 44 hours ago

A few days away keeps your troubles at bay, and Downtown Cincinnati is the perfect place to visit. Interesting monuments, scrumptious eats, and opportunities to capture marvelous photos: these are just a few of the benefits of visiting Downtown Cincinnati. You'll treat yourself to the city's best food, marvel at the top monuments and landmarks in the region, and enjoy the most exciting shows. Naturally, you'll book a room at a luxury hotel! Extravagant experiences are right up your alley, so get your elegant hotel in Downtown Cincinnati on Expedia.com today and start your vacation off on the right (well-dressed) foot.

5-Star Vacations in Downtown Cincinnati

If you need any proof that Downtown Cincinnati is filled with amazing things to do, you should know that plenty of folks choose to live here. Whether you’re looking to spend your vacation dining on the best regional fare or exploring museums in Downtown Cincinnati, you'll never be disappointed. Downtown Cincinnati is full of dreamy hotels on top of appealing attractions, so you can count on a wonderful stay. Book early to get the best room!

An upscale vacation calls for facials, culture, and activities from your bucket list. When you're smart enough to book travel on Expedia.com, you never have to limit yourself. Thanks to our hotel deals, your bucket list budget will still be intact. After many hours of sightseeing, your luxury hotel is waiting with spectacular food and impressive amenities. Take advantage of amenities like an oversized bathtub or indoor pool before the day is through. The luxury hotels in Downtown Cincinnati will lull you into a state of relaxation before you know it.

Luxury Hotels in Downtown Cincinnati

When you’ve got your heart set on making the most of your gratifying getaway in Downtown Cincinnati, Expedia.com is here to help. Browse the abundance of reviews on fantastic hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and VIP services. Some of the city's 5-star accommodations even feature impeccable penthouses, while others offer reinvigorating spa treatments. Use our mobile booking app to choose a fabulous 5-star hotel in Downtown Cincinnati, and soon you'll be soaking up luxury in style!