Title: Seneca Station Accommodation - Find the 10 Best Hotels near Seneca Station, Buffalo | Book on Expedia.com [Downtown Buffalo Travel Guide](https://expedia.com/Buffalo-Downtown-Buffalo.dx6056533)[Car Rentals in Downtown Buffalo](https://expedia.com/Car-Rentals-In-Downtown-Buffalo.d6056533.Car-Rental-Guide)[Downtown Buffalo Vacation Packages](https://expedia.com/Downtown-Buffalo.d6056533.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 12 - Feb 13](https://www.expedia.com/Hotel-Search?regionId=6257228&startDate=2026-02-12&endDate=2026-02-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 13 - Feb 14](https://www.expedia.com/Hotel-Search?regionId=6257228&startDate=2026-02-13&endDate=2026-02-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=6257228&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6257228&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Seneca Station hotels ![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/7bda029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Robin Room | Premium bedding, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/091461c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/e6c5cf14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/33860f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Harmony House [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) Allentown, 1.4 mi from Seneca Station 10/10 Exceptional (47 reviews) "Amazing breakfasts!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David $263 nightly $302 total Feb 17 - Feb 18 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Harmony-House.h90762810.Hotel-Information) ![55-inch Smart TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/01caede6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/bc225fe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/610165f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/b448fbab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Marriott at LECOM HARBORCENTER [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Marriott-At-LECOM-HARBORCENTER.h9787810.Hotel-Information) Downtown Buffalo, 0.3 mi from Seneca Station 9.4/10 Exceptional (906 reviews) "Fabulous room and great service. We love staying here!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jordan $212 nightly $247 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Marriott-At-LECOM-HARBORCENTER.h9787810.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/aba5ffc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot springs](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/f730f1f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/ae3eb39b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/0539858c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Curtiss Hotel, an Ascend Collection Hotel [](https://www.expedia.com/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) Buffalo Theater District, 0.5 mi from Seneca Station 9.4/10 Exceptional (1,001 reviews) "Great hotel 5 \*\*\*\*\*" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daveisha $246 nightly $287 total Feb 16 - Feb 17 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Curtiss-Hotel.h17038248.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite, 1 Queen Bed (Premium Room (Fireplace Grand Queen)) | Hypo-allergenic bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/37ec72a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/28123e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/545d734b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mansion On Delaware Ave [](https://www.expedia.com/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) Allentown, 1 mi from Seneca Station 9.4/10 Exceptional (1,000 reviews) "great staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen $167 nightly $192 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-The-Mansion-On-Delaware-Ave.h692610.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/40ce07c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/7dd5c347.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/957e497d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/865c992e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Buffalo Downtown / Canalside [](https://www.expedia.com/Buffalo-Hotels-Courtyard-Buffalo-Downtown-Canalside.h7901087.Hotel-Information) Downtown Buffalo, 0.3 mi from Seneca Station 9.0/10 Wonderful (970 reviews) "Large clean room and very clean hotel." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Paolo $173 nightly $202 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Courtyard-Buffalo-Downtown-Canalside.h7901087.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/841778b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness studio](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/9e9840d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/c59b8ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/14000000/13460000/13451300/13451237/26451150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Buffalo [](https://www.expedia.com/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information) Buffalo Theater District, 0.6 mi from Seneca Station 9.2/10 Wonderful (407 reviews) "Immaculate hotel. All around good service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Prince $259 nightly $302 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-The-Westin-Buffalo.h13451237.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/3b4ec85c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch LCD TV with cable channels, TV, printers](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/1bc51aa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/ee5d0f12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/bc526b34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Buffalo Downtown [](https://www.expedia.com/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) Buffalo Theater District, 0.6 mi from Seneca Station 8.8/10 Excellent (1,011 reviews) "Super clean, great location and cozy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine $151 nightly $176 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/99e060a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/873ad6ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/801e8ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Garden Buffalo Downtown [](https://www.expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) Downtown Buffalo, 1.4 mi from Seneca Station 9.0/10 Wonderful (1,753 reviews) "Randy and Sierra were both wonderful and friendly. The rooms were great, the location was lovely. Overall great stay. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Christopher $124 nightly $144 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/e053ab2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/97ef24da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/20f6c548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/f345559b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Buffalo Downtown [](https://www.expedia.com/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) Buffalo Theater District, 0.3 mi from Seneca Station 8.6/10 Excellent (1,015 reviews) "Great hotel!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Suzanne $116 nightly $139 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/debc1f3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/ec4765b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, Half Bath | Premium bedding, free WiFi, bed sheets](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/7b15265b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/22d12e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Guesthouse [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information) Allentown, 1.3 mi from Seneca Station 9.0/10 Wonderful (128 reviews) "Great staff, and the accommodations were very pleasant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany $134 nightly $154 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-26&endDate=2026-02-27®ionId=6257228&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_6257228) ## Compare popular hotels close to Seneca Station | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | --------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Reception](https://images.trvl-media.com/lodging/91000000/90770000/90762900/90762810/7bda029a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Buffalo Harmony House | 4.5 star property | 10.0Exceptional47 reviews | View | | | | | | | ![55-inch Smart TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/10000000/9790000/9787900/9787810/01caede6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Buffalo Marriott at LECOM HARBORCENTER | 3.5 star property | 9.4Exceptional906 reviews | View | | | | | | | ![Free daily continental breakfast](https://images.trvl-media.com/lodging/18000000/17040000/17038300/17038248/aba5ffc3.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Curtiss Hotel, an Ascend Collection Hotel | 5.0 star property | 9.4Exceptional1,001 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/700000/692700/692610/1225a495.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Mansion On Delaware Ave | 4.0 star property | 9.4Exceptional1,000 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/8000000/7910000/7901100/7901087/40ce07c6.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Courtyard Buffalo Downtown / Canalside | 3.0 star property | 9.0Wonderful970 reviews | View | | | | | | ## Top Seneca Station Hotel Reviews ![Hampton Inn & Suites Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/900000/892600/892571/3b4ec85c_y.jpg) ### Hampton Inn & Suites Buffalo Downtown 10/10 Excellent "Yes" [](https://expedia.com/Buffalo-Hotels-Hampton-Inn-Suites-Buffalo-Downtown.h892571.Hotel-Information) ![Hilton Garden Inn Buffalo Downtown](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/7db896c2_y.jpg) ### Hilton Garden Inn Buffalo Downtown 10/10 Excellent "Spacious rooms. Clean rooms. Friendly staff" [](https://expedia.com/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) ![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/2e0799e1_y.jpg) ### Wyndham Garden Buffalo Downtown 10/10 Excellent "Randy and Sierra were both wonderful and friendly. The rooms were great, the location was lovely. Overall great stay. " [](https://expedia.com/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information) ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Staff was very helpful and the rooms were clean." [](https://expedia.com/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Home2 Suites by Hilton Buffalo Airport / Galleria Mall](https://images.trvl-media.com/lodging/11000000/10630000/10627700/10627666/e4026590_y.jpg) ### Home2 Suites by Hilton Buffalo Airport / Galleria Mall 10/10 Excellent "Good customer service, clean, great amenities. " [](https://expedia.com/Buffalo-Hotels-Home2-Suites-By-Hilton-Buffalo-Airport-Galleria-Mall.h10627666.Hotel-Information) ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 10/10 Excellent "Great check in experience, clean rooms, close to everything downtown and the pool on the 11th floor with great views is a bonus. " [](https://expedia.com/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62_y.jpg) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG 10/10 Excellent "Very clean and friendly staff" [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ![Hotel at the Lafayette Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/6000000/5060000/5058700/5058670/ce7e42e7_y.jpg) ### Hotel at the Lafayette Trademark Collection by Wyndham 10/10 Excellent "Very roomy, nice & clean. I would highly recommend this hotel. Would stay here again. Please note that if you leave and have a night out, door is locked and you will need to be buzzed in. I would enquire if you plan to leave the hotel and come back late." [](https://expedia.com/Buffalo-Hotels-Hotel-At-The-Lafayette-Trademark-Collection-By-Wyndham.h5058670.Hotel-Information) ![Holiday Inn Express Cheektowaga North East by IHG](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69_y.jpg) ### Holiday Inn Express Cheektowaga North East by IHG 10/10 Excellent " z”." [](https://expedia.com/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) ## Frequently asked questions ### What's the area like around Seneca Station? ### What's the best hotel to stay near Seneca Station? ### How many hotels will I be able to find close to Seneca Station? ### What can I see and do near Seneca Station? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Buffalo Hotels ](https://www.expedia.com/Buffalo-Hotels.d602674.Travel-Guide-Hotels) - [Cheap Hotels in Buffalo ](https://www.expedia.com/Buffalo-Hotels-Cheap-Hotels.0-0-d602674-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near Downtown Buffalo ](https://www.expedia.com/Downtown-Buffalo-Buffalo-Hotels.0-n6056533-0.Travel-Guide-Filter-Hotels) - [Hotels near KeyBank Center ](https://www.expedia.com/KeyBank-Center-Hotels.0-l6064435-0.Travel-Guide-Filter-Hotels) - [Hotels near Sahlen Field ](https://www.expedia.com/Sahlen-Field-Hotels.0-l6064401-0.Travel-Guide-Filter-Hotels) - 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