Osco Vacation Rentals

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Vacation Rentals in Osco

Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.
10.0 out of 10, Exceptional, (57)
"We loved our stay. Clean, quiet, and the owners were very accommodating to our needs. We plan to be back next year. "
United States
Anthony
Rustic and Secluded 1 Bedroom Cabin Retreat. Located on Private Stocked Pond.
Charming 1920s, pet friendly home, centrally located!
9.2 out of 10, Wonderful, (28)
"Charming older home great when traveling with a pet. Host was very accommodating and responsive. "
United States
Andrea M.
$205 nightly
The price is $229
Oct 26 - Oct 27
Total with taxes and fees
Charming 1920s, pet friendly home, centrally located!
Minutes from anywhere
10.0 out of 10, Exceptional, (122)
"Great place, great location and great host. Will stay here again if I’m ever in the area."
United States
Bob P.
$82 nightly
The price is $87
Nov 3 - Nov 4
Total with taxes and fees
Minutes from anywhere
3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!
10.0 out of 10, Exceptional, (34)
"Very clean with plenty of space for everyone. And in an ideal location"
United States
Brian S.
$274 nightly
The price is $307
Oct 26 - Oct 27
Total with taxes and fees
3BR/2BA Beauty near TBK sports complex. Right off I74, close to everything!
Riverboat Paradise
10.0 out of 10, Exceptional, (45)
"2nd time staying here and enjoyed thoroughly both times. Super clean place and great view of the river. Small town that stays quiet but still is fun. "
United States
Bruce S.
Riverboat Paradise
Lucy’s House Single Family Bungalow
9.6 out of 10, Exceptional, (77)
"We came to Moline for a quick family reunion. Lucy’s house was so welcoming and comfortable it was the perfect place to relax. We would certainly stay there again. "
United States
Pamela R.
$119 nightly
The price is $126
Oct 26 - Oct 27
Total with taxes and fees
Lucy’s House Single Family Bungalow
Relax on the Rock River in fall, book our cozy 1-bedroom cabin!
9.6 out of 10, Exceptional, (33)
"Absolutely Amazing stay!!!"
United States
Joseph R.
Relax on the Rock River in fall, book our cozy 1-bedroom cabin!
Home on Historic Campbell's Island with Mighty Mississippi River in the backyard
9.4 out of 10, Exceptional, (6)
"House is exactly what we needed! Pull out couch, free parking, and beautiful view."
United States
Emily W.
Home on Historic Campbell's Island with Mighty Mississippi River in the backyard
Historical riverfront home in beautiful LeClaire. Kid and pet friendly!
9.4 out of 10, Exceptional, (9)
"The stay was exactly as stated in the description and met every expectation. The location in downtown Le Claire was a bonus."
United States
Brian S.
$211 nightly
The price is $236
Oct 25 - Oct 26
Total with taxes and fees
Historical riverfront home in beautiful LeClaire. Kid and pet friendly!
River Front House
8.0 out of 10, Very Good, (21)
"The owner was easy to get in touch with and very helpful. My coworker and I stayed here for a 3 week job."
United States
Lauren K.
$214 nightly
The price is $227
Oct 26 - Oct 27
Total with taxes and fees
River Front House
Renwick Mansion Guest House
9.6 out of 10, Exceptional, (84)
"Our stay was great! The owners were very friendly and helpful. The house is beautiful and inviting. It is in a great location for things to do. We would definitely stay here again!"
United States
Michelle
Renwick Mansion Guest House
Historic Cottage in LeClaire w/full river views and 3 decks. Dogs welcome
10.0 out of 10, Exceptional, (75)
"Cozy and beautiful space that we enjoyed immensely!"
United States
Nadine Z.
$260 nightly
The price is $291
Oct 26 - Oct 27
Total with taxes and fees
Historic Cottage in LeClaire w/full river views and 3 decks. Dogs welcome
The Nelson Lofts Penthouse (2BR)
10.0 out of 10, Exceptional, (9)
"Very cool industrial feel with great views. Easy access to everything downtown."
United States
Tim O.
The Nelson Lofts Penthouse (2BR)
Luxurious Condo family-friendly Closer to attractions! Eatery,Walmart&lot more!
$320 nightly
The price is $339
Oct 26 - Oct 27
Total with taxes and fees
Luxurious Condo family-friendly Closer to attractions! Eatery,Walmart&lot more!
The Nelson Lofts - Unit 6 (1 BR)
10.0 out of 10, Exceptional, (11)
"Wonderful property, very clean. Great communication from the host. Would definitely stay here again"
United States
Ravinder B.
$200 nightly
The price is $224
Oct 26 - Oct 27
Total with taxes and fees
The Nelson Lofts - Unit 6 (1 BR)
The Nelson Lofts - Unit 7 (2 BR)
9.6 out of 10, Exceptional, (25)
"We had a wonderful week of family time in the quad cities. This apartment was perfect for our needs- great location, great size and very modern and comfortable! Highly recommend!"
United States
Geri M.
$247 nightly
The price is $277
Oct 26 - Oct 27
Total with taxes and fees
The Nelson Lofts - Unit 7 (2 BR)
Unique Barnhouse complete with silo!
9.8 out of 10, Exceptional, (16)
"We had a wonderful stay at the farmhouse. Very spacious, clean with a homey, lived in feeling! "
United States
Laurie B.
Unique Barnhouse complete with silo!
Hot Tub River Views
10.0 out of 10, Exceptional, (49)
"Such a great, put together house on the River!! It was perfect for our family weekend getaway "
United States
Shelby S.
Hot Tub River Views
Great Location Great Value! 4 bedroom 2 full bath home in East Village
9.8 out of 10, Exceptional, (55)
"Great location!"
United States
Emily C.
Great Location Great Value! 4 bedroom 2 full bath home in East Village
Island House On Mississippi River
8.0 out of 10, Very Good, (35)
"The home was a perfect size for a get away for our family. The ruvwr was fun to watch and it was a quiet neighborhood."
United States
Jennifer S.
Island House On Mississippi River
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Osco Hotel Reviews

Find out more about Osco

Everything you need to know about Osco vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Osco vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Osco vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Osco vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Osco. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Osco in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $87 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Osco rentals

At Expedia, we put the best Osco vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Osco rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Osco vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Osco. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Osco?

Yes, you can find vacation rentals near popular local attractions in Osco, or you can select a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in Osco?

Charming 1920s, pet friendly home, centrally located! : Visitors like this Osco vacation home rental. It is equipped with a selection of games, air-conditioning, and WiFi to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Osco?

Explore the area and family-friendly sights such as Niabi Zoo, or get out into nature at a spot like Greenvalley Sports Complex. TPC Deere Run Golf Course and Deere and Company World Headquarters are a couple of places you'll find in the larger area.

What’s a vacation rental in Osco like?

Vacation rentals are privately owned properties you can stay in for short or long periods in Osco. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of safety away from public hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for families.