DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.

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Top Cities in Orangeburg County

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Our top choices for Orangeburg County hotels

1. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,465 reviews)
"Great overnight stop"
United States
Gary
$75 nightly
The price is $83
Jun 11 - Jun 12
Total with taxes and fees
Baymont by Wyndham Santee

2. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (851 reviews)
"Great bed and breakfast. Didn’t realize until after we purchased dinner outside the hotel that there was a small food court for sandwiches, snacks etc"
United States
Marie
$106 nightly
The price is $118
Jun 21 - Jun 22
Total with taxes and fees
Tru By Hilton Santee

3. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,010 reviews)
"Excellent place to stay"
United States
Bartolo
$114 nightly
The price is $127
Jun 24 - Jun 25
Total with taxes and fees
Tru by Hilton Orangeburg

4. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,002 reviews)
"Pet friendly and next door to Cracker Barrel."
United States
Timothy M.
$95 nightly
The price is $106
Jul 5 - Jul 6
Total with taxes and fees
Spark by Hilton Orangeburg

5. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,012 reviews)
"Nice hotel stay, excellent staff and accommodations."
United States
Carl
$134 nightly
The price is $149
Jun 17 - Jun 18
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee

6. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,005 reviews)
"Wonderful stay!"
United States
Joie
$79 nightly
The price is $88
Jun 11 - Jun 12
Total with taxes and fees
Travelodge by Wyndham Orangeburg

7. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,007 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
$110 nightly
The price is $122
Jun 21 - Jun 22
Total with taxes and fees
Best Western Plus Santee Inn

8. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (538 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
$60 nightly
The price is $67
Jul 1 - Jul 2
Total with taxes and fees
Quality Inn & Suites Santee I-95

9. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,006 reviews)
"Nice breakfast, rooms spacious, convenient location"
United States
Gloria
$119 nightly
The price is $132
Jun 21 - Jun 22
Total with taxes and fees
Hampton Inn Santee-I-95

10. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (766 reviews)
"Great location, spacious rooms, amazing breakfast."
United States
Pamela
$114 nightly
The price is $126
Jun 17 - Jun 18
Total with taxes and fees
SpringHill Suites by Marriott Orangeburg

11. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,009 reviews)
"This property is right off the interstate with no traffic. The staff was very friendly and the hotel was clean. Breakfast and coffee were delicious. Highly recommend "
United States
Kimberley
$103 nightly
The price is $114
Jun 21 - Jun 22
Total with taxes and fees
Comfort Inn & Suites Santee

12. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (782 reviews)
"Great stay!!"
United States
Laylany
$116 nightly
The price is $129
Jun 11 - Jun 12
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg

13. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (832 reviews)
"Love the staff! Very welcoming. Best breakfast."
United States
Beverly
$112 nightly
The price is $124
Jun 14 - Jun 15
Total with taxes and fees
Holiday Inn Express & Suites Orangeburg by IHG

14. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (669 reviews)
"Clean room the staffs was very professional"
United States
Curtis
$60 nightly
The price is $66
Jul 5 - Jul 6
Total with taxes and fees
Quality Inn & Suites Orangeburg

15. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (805 reviews)
"The stay was great."
United States
Brandon
$130 nightly
The price is $145
Jul 2 - Jul 3
Total with taxes and fees
Hampton Inn & Suites Orangeburg

16. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very Good, (1,000 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
$102 nightly
The price is $113
Jun 28 - Jun 29
Total with taxes and fees
Holiday Inn Santee by IHG

17. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (739 reviews)
"Staff was very friendly. "
United States
Sriram
$63 nightly
The price is $70
Jun 11 - Jun 12
Total with taxes and fees
Travelodge by Wyndham Santee

18. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,002 reviews)
"Clean rooms enjoyed my stay."
United States
Rontisha
$56 nightly
The price is $62
Jul 5 - Jul 6
Total with taxes and fees
Baymont by Wyndham Orangeburg North

19. Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
7.0 out of 10, Good, (989 reviews)
"Coffee not great okay breakfast Room was comfortable for an overnight stay"
United States
sandra
$59 nightly
The price is $66
Jul 1 - Jul 2
Total with taxes and fees
Super 8 by Wyndham, Orangeburg

20. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
$92 nightly
The price is $102
Jun 11 - Jun 12
Total with taxes and fees
Bells Marina & Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Orangeburg County, SC

Showing deals for:Jun 19 - Jun 21

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Top Orangeburg County Hotel Reviews

Price trends for hotels in Orangeburg County

Less expensive
More expensive
This month
Next month
May
June
$109
$108
Month
Price
January
$87
February
$96
March
$91
April
$93
May
$66
June
$109
July
$108
August
$94
September
$98
October
$93
November
$91
December
$85
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Orangeburg County. Select dates and complete search for nightly totals inclusive of taxes and fees.

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Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from $62 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 72ºF and 90ºF. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at $62 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed vacation at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveler experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Book an Orangeburg County hotel with Expedia for choice, price and ease. Also, our One Key™ rewards program lets you earn OneKeyCash™* on eligible hotels, vacation rentals, flights, car rentals and more. In addition, we offer flexibility in case your itinerary changes, and if you want to ask us anything or need assistance, our online Help Center is always available. *OneKeyCash disclaimer - OneKeyCash is not redeemable for cash and can only be used on Hotels.com, Expedia and Vrbo.