A historic building with ornate architecture and a modern brick structure in the foreground.

Find all hotels by Independent in Uptown, OH

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Oct 1 - Oct 2
Tomorrow
Oct 2 - Oct 3
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11
Save an average of 15% on thousands of hotels when you're signed in

Top Uptown Hotel Reviews

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

10/10 Excellent
"Great Hotel!!!!! Amazing!!"
Kolin 1-night trip
Posted 1 hour ago
21c Museum Hotel Cincinnati
LivINN Hotel Cincinnati / Sharonville Convention Center

LivINN Hotel Cincinnati / Sharonville Convention Center

8/10 Good
"This property was decent for the price and overnight stay we needed."
Abbie 1-night trip
Posted 2 hours ago
LivINN Hotel Cincinnati / Sharonville Convention Center
Days Inn by Wyndham Florence Cincinnati Area

Days Inn by Wyndham Florence Cincinnati Area

8/10 Good
"Very comfy bed, cold air and great shower pressure."
bryan 3-night trip
Posted 2 hours ago
Days Inn by Wyndham Florence Cincinnati Area
Holiday Inn Express & Suites Cincinnati Riverfront by IHG

Holiday Inn Express & Suites Cincinnati Riverfront by IHG

10/10 Excellent
"Everything was perfect!"
Laura 1-night trip
Posted 3 hours ago
Holiday Inn Express & Suites Cincinnati Riverfront by IHG
Ashley Quarters Hotel Cincinnati Airport

Ashley Quarters Hotel Cincinnati Airport

8/10 Good
"Great price"
Edna 3-night trip
Posted 4 hours ago
Ashley Quarters Hotel Cincinnati Airport
Radisson Hotel Cincinnati Riverfront

Radisson Hotel Cincinnati Riverfront

10/10 Excellent
"Paid for a city view this time, and it was definitely worth it!! This hotel always comes through!"
Katie 1-night trip
Posted 8 hours ago
Radisson Hotel Cincinnati Riverfront
Drury Plaza Hotel Cincinnati Florence

Drury Plaza Hotel Cincinnati Florence

10/10 Excellent
"Everything was exceptional. My wife, however, was bothered slightly by the smell of the linen likely related to the detergent used in the cleaning process. We're planning to make this hotel location a regular stop on our future road trips."
Stephen 1-night trip
Posted 11 hours ago
Drury Plaza Hotel Cincinnati Florence
The Westin Cincinnati

The Westin Cincinnati

8/10 Good
"The elevator system was a nightmare. Staff was very helpful though."
Austin 1-night trip
Posted 15 hours ago
The Westin Cincinnati
Hollywood Casino & Hotel

Hollywood Casino & Hotel

8/10 Good
"Staff was great, room was great. Only problem no one informed us about the train tracks outside r room. It would have been nice otherwise other side of the hotel. Plenty of slots to play and the food court was good also."
Robert 1-night trip
Posted 1 day ago
Hollywood Casino & Hotel

Find out more about Uptown

Uptown, Cincinnati Hotel Guide

About 3 miles north from the downtown pulse of Cincinnati, United States of America, is Uptown.

Want to add a few of Cincinnati's most awesome attractions to your to-do list? You won't want to miss the Krohn Conservatory, the Cincinnati Art Museum and the Cincinnati Zoo and Botanical Garden.

There are a lot of Uptown places to base yourself within strolling distance of Krohn Conservatory, such as the 21c Museum Hotel Cincinnati, Residence Inn by Marriott Cincinnati Downtown/The Phelps, The Westin Cincinnati, Cincinnatian Hotel and Marriott Cincinnati RiverCenter.

Take a tour of Harriet Beecher Stowe House, an important historic house that you are able to see from the inside. If you'd like to stay a stone’s throw away from this sight, check out the Hampton Inn and Suites Cincinnati/Uptown-University Area and Hopkins Park Bed and Breakfast. Eden Park is a pleasant spot where you can truly unwind and live in the moment. It’s possible to spend your nights nearby. Among the most popular accommodation options here are the Courtyard by Marriott Cincinnati-Covington and Holiday Inn Cincinnati-Riverfront.

If you're craving a shot of caffeine to help you get through all that exploring, Starbucks is among the most well-known places in Uptown to get your fix. Still feeling hungry? Caminetto Bistro is also in the area and offers some heartier fare. Fries Cafe is a cheerful local hangout to drink a wine or beer once the sun sets.

Accommodation options near Uptown

For alternative accommodation options, you can explore Expedia's St. Bernard hotels guide. St. Bernard lies 2 miles to the north of central Uptown. Another Cincinnati area to put on your radar is Downtown Cincinnati. It’s 2 miles from Uptown.

An unforgettable trip is just a few mouse clicks away. Our Cincinnati vacation travel guide and Cincinnati hotels page will help you plan and get the most out of your adventure.

Explore a world of travel with Expedia