Title: Top 10 Hotels in Vanduser, MO from $55 - Competitive Prices | Expedia.com

[Vacation Rentals in Vanduser](https://expedia.com/Vanduser-Vacation-Rentals.d553248634983298513.Travel-Guide-VacationRentals)[Car Rentals in Vanduser](https://expedia.com/Car-Rentals-In-Vanduser.d553248634983298513.Car-Rental-Guide)[Vanduser Vacation Packages](https://expedia.com/Vanduser.d553248634983298513.Destination-Travel-Guides)

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## Go beyond your typical stay in Vanduser

Pet-friendly

[](https://www.expedia.com/Hotel-Search?destination=Vanduser%2C+Missouri%2C+United+States+of+America&regionId=553248634983298513&latLong=36.990605%2C-89.685638&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&amenities=PETS)

Pool

[](https://www.expedia.com/Hotel-Search?destination=Vanduser%2C+Missouri%2C+United+States+of+America&regionId=553248634983298513&latLong=36.990605%2C-89.685638&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&amenities=POOL)

## Check prices for these dates

Tonight

[Mar 2 - Mar 3](https://www.expedia.com/Hotel-Search?regionId=553248634983298513&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 3 - Mar 4](https://www.expedia.com/Hotel-Search?regionId=553248634983298513&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248634983298513&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248634983298513&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Vanduser hotels

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/95135562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Sikeston, MO

[](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

Sikeston

9.4/10

Exceptional

(1,007 reviews)

"As always it was a perfect visit"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$94 nightly

$108 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/e959f8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Sikeston

[](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

Sikeston

9.4/10

Exceptional

(60 reviews)

"Clean rooms great staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

IRA

$101 nightly

$114 total

Mar 12 - Mar 13

Total with taxes and fees

[](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

[](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

Sikeston

8.6/10

Excellent

(448 reviews)

"Stay was excellent "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kourtney

$93 nightly

$105 total

Mar 22 - Mar 23

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/594efec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

[](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

Sikeston

8.4/10

Very Good

(747 reviews)

"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Becky

$65 nightly

$75 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/cbe2898d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Sikeston

[](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

Sikeston

9.0/10

Wonderful

(493 reviews)

"Very Clean room, friendly staff, breakfast in the morning. Will be staying again! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Affinity

$95 nightly

$108 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/327b8d22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Sikeston I-55

[](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

Sikeston

8.4/10

Very Good

(1,005 reviews)

"Great stay, everything was clean and comfortable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Charles

$82 nightly

$93 total

Mar 26 - Mar 27

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/fcfb42b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TownePlace Suites by Marriott Sikeston

[](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

Sikeston

9.2/10

Wonderful

(12 reviews)

"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jason

$118 nightly

$134 total

Mar 12 - Mar 13

Total with taxes and fees

[](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information)

![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/8fe9a2cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn and Suites by Wyndham Sikeston

[](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

Sikeston

7.2/10

Good

(1,003 reviews)

"Everything was excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

$68 nightly

$77 total

Mar 4 - Mar 5

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/4da73ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/07d69819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7a78d337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/7657c6fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Sikeston I-55

[](https://www.expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

Sikeston

8.4/10

Very Good

(288 reviews)

"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

aileen

$94 nightly

$107 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/392abeff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Yard Inn and Suite

[](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information)

Sikeston

6.8/10

(124 reviews)

"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrew

$49 nightly

$55 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information)

![Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/55187aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/97dfc357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/cc9ac69a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Sikeston/Miner Area

[](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

Sikeston

6.8/10

(598 reviews)

"Great place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Misty

$61 nightly

$70 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Vanduser Hotel Reviews

![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da_y.jpg)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"The room was large, the beds comfortable. The pool was GREAT. Breakfast was awesome. We had a great stay."

[](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg)

### Hampton Inn Sikeston

10/10 Excellent

"Clean room "

[](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Yes"

[](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg)

### Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"Great clean and quiet room "

[](https://expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Charming 3-bedroom house in delightful Advance with AC, WiFi](https://images.trvl-media.com/lodging/104000000/103370000/103362500/103362449/a162857d_y.jpg)

### Charming 3-bedroom house in delightful Advance with AC, WiFi

10/10 Excellent

"Very nice and cute house with plenty of room and amenities. Would definitely stay here again!"

[](https://expedia.com/Advance-Hotels-Charming-3-Bedroom-House-In-Delightful-Advance-With-AC.h103362449.Hotel-Information)

![Comfort Inn & Suites Sikeston I-55](https://images.trvl-media.com/lodging/2000000/1810000/1804500/1804447/6afdbde2_y.jpg)

### Comfort Inn & Suites Sikeston I-55

10/10 Excellent

"facility was very clean. night staff was a pleasure and most helpful. very nice room with lots of space. great stay! good breakfast as well."

[](https://expedia.com/Sikeston-Hotels-Comfort-Inn-Suites-Sikeston-I-55.h1804447.Hotel-Information)

![Fairfield Inn & Suites by Marriott Sikeston](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/cffe72cf_y.jpg)

### Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent

"The room was spotless and the staff was really friendly "

[](https://expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information)

![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg)

### Best Western Plus Sikeston

10/10 Excellent

"Very nice folks who manage the hotel!!"

[](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg)

### Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"The room was spotless, the staff was very good and helpful. I loved my stay. I recommend Drury Inn to all my family and friends. "

[](https://expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

## More cheap stays in Vanduser

![Country Yard Inn and Suite](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7b36182_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Country Yard Inn and Suite

110 South Interstate Drive Sikeston MO

$49 nightly

$55 total

Mar 25 - Mar 26

Total with taxes and fees

[](https://expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information)

![Super 8 by Wyndham Sikeston/Miner Area](https://images.trvl-media.com/lodging/1000000/860000/855500/855478/d9ee28fe_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$61 nightly

$70 total

Mar 8 - Mar 9

Total with taxes and fees

6.8/10 (598 reviews)

[](https://expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-SikestonMiner-Area.h855478.Hotel-Information)

![Days Inn and Suites by Wyndham Sikeston](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/e12b74a2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$68 nightly

$77 total

Mar 4 - Mar 5

Total with taxes and fees

7.2/10 Good! (1,003 reviews)

[](https://expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information)

![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Sikeston

120 S Interstate Drive Sikeston MO

$82 nightly

$93 total

Mar 26 - Mar 27

Total with taxes and fees

8.4/10 Very Good! (1,005 reviews)

[](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Holiday Inn Express & Suites Sikeston Southwest by IHG](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/3aa729da_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

$93 nightly

$105 total

Mar 22 - Mar 23

Total with taxes and fees

8.6/10 Excellent! (448 reviews)

[](https://expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

$95 nightly

$108 total

Mar 29 - Mar 30

Total with taxes and fees

9/10 Wonderful! (493 reviews)

[](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

## Hotels in Vanduser with star-rating

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

3 properties

[](https://expedia.com/3Star-Vanduser-Hotels.s30-0-d553248634983298513.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

9 properties

[](https://expedia.com/2Star-Vanduser-Hotels.s20-0-d553248634983298513.Travel-Guide-Filter-Hotels)

## Frequently asked questions

### What is the best area to stay in Vanduser?

> Vanduser is a small, quiet town, so the "best" area is generally defined by its proximity to the few local establishments. Main Street serves as the primary thoroughfare, where you'll find the town's small businesses and community gathering spots. The layout is straightforward, making it easy to navigate on foot.
> 
>   
> For solo travelers or couples seeking a quiet retreat and a taste of small-town life, staying near Main Street offers the most convenience. You'll be within walking distance of any local eateries and shops, allowing for a relaxed pace.

### When is the best time to go to Vanduser?

> During spring, the temperatures are mild, typically ranging from the 60s to 70s Fahrenheit (15-25 Celsius). This season is ideal for outdoor activities, as the local flora is in bloom, offering scenic views for walks or drives through the rural landscape. Travelers interested in local agriculture might appreciate seeing the early stages of crop growth.
> 
>   
> Fall also offers comfortable temperatures, generally from the 50s to 70s Fahrenheit (10-20 Celsius), and is known for its clear skies and colorful foliage. This is a great time for those seeking a peaceful retreat or wishing to experience the local harvest festivals, which often take place in nearby towns.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Vanduser hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Vanduser hotel?

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