A steel bridge with a sunset in the background.

Cairo Vacation Rentals

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Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Cairo vacation rentals

A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

1. Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (37 reviews)
"Great place in a beautiful location. "
United States
George B.
$205 nightly
The price is $217
Sep 28 - Sep 29
Total with taxes and fees
Peaceful secluded cabin located near Horseshoe Lake
A cozy room with a wooden table and chairs, a large window, and a door with a sign.

2. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (43 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
$133 nightly
The price is $140
Oct 4 - Oct 5
Total with taxes and fees
Cozy cabins on beautiful Horseshoe Lake
A small, single-story building with a wooden exterior and large windows.

3. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
$133 nightly
The price is $140
Oct 5 - Oct 6
Total with taxes and fees
The Rested Duck Mallard Room
A room with a pool table, a sofa, and a dining table with chairs.

4. Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge

Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
Villa Ridge
10.0 out of 10, Exceptional, (3 reviews)
"The location is lovely and peaceful. The cabin is clean, comfortable and relaxing. We enjoyed the pool table and ping pong."
United States
Michelle U.
$252 nightly
The price is $267
Sep 25 - Sep 26
Total with taxes and fees
Peaceful 2-bedroom cabin with AC in welcoming Villa Ridge
A modern kitchen with a built-in microwave, stainless steel appliances, and a sink.

5. Charming Home just minutes from Interstate and Mall

Charming Home just minutes from Interstate and Mall
Kevil
10.0 out of 10, Exceptional, (25 reviews)
"Location was great. Beds were so comfortable, place was so clean and nice. Very cute place to stay. Would stay here again!"
United States
Deannena H.
$182 nightly
The price is $206
Sep 28 - Sep 29
Total with taxes and fees
Charming Home just minutes from Interstate and Mall
A bedroom with a bed, a nightstand, a bedside table, a floor lamp, a ceiling fan, and a sliding door leading to a bathroom.

6. Welcoming 4-bedroom house with AC in charming La Center

Welcoming 4-bedroom house with AC in charming La Center
La Center
10.0 out of 10, Exceptional, (2 reviews)
"We stayed here while working on a project, and it was honestly one of the best stays I’ve had. The house was super clean, the beds were very comfortable, and the air conditioning worked great. The neighborhood felt safe, the neighbors were friendly, and the location was very convenient with a grocery store just a couple blocks away and a great pizza place nearby.I would definitely stay here again. Highly recommend!"
United States
Tom R.
$243 nightly
The price is $260
Sep 28 - Sep 29
Total with taxes and fees
Welcoming 4-bedroom house with AC in charming La Center
A bedroom with a bed, a nightstand, a wall-mounted TV, and a door.

7. The Roost | Hot Tub, Ponds & Farm Views

The Roost | Hot Tub, Ponds & Farm Views
Carlisle County
$198 nightly
The price is $208
Oct 3 - Oct 4
Total with taxes and fees
The Roost | Hot Tub, Ponds & Farm Views
A wooden deck with a colorful rug featuring a tiger design, a white metal chair, and a door.

8. Perfect Couples Retreat - firepit

Perfect Couples Retreat - firepit
Carlisle County
$178 nightly
The price is $186
Sep 27 - Sep 28
Total with taxes and fees
Perfect Couples Retreat - firepit
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

9. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
Cunningham
10.0 out of 10, Exceptional, (4 reviews)
"Host was great. "
United States
Sheila C.
$278 nightly
The price is $298
Sep 28 - Sep 29
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

10. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
$271 nightly
The price is $290
Sep 28 - Sep 29
Total with taxes and fees
Quiet Country Stay: Modern Home Near Paducah
A serene outdoor area with a pond, surrounded by trees and a grassy lawn. There are two wooden benches facing the water.

11. Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (106 reviews)
"Such a beautiful and peaceful place to stay Suzzie is a great host I stay there once or twice a year for the past several years loved every minute can’t wait to go back"
United States
Paul D.
$239 nightly
The price is $253
Sep 25 - Sep 26
Total with taxes and fees
Charming cottage overlooking Lake Acre
A compact interior with a table and bench seating, a window with blinds, and a door with a handle.

12. Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.

Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.
La Center
$90 nightly
The price is $96
Sep 28 - Sep 29
Total with taxes and fees
Cozy 1-bedroom recreational vehicle in peaceful La Center. Sleeps 5.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cairo Hotel Reviews

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent
"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"
Brianna 1-night trip
Posted 3 days ago
Super 8 by Wyndham Charleston/Sikeston East MO

Find out more about Cairo

Everything you need to know about Cairo vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Cairo vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Cairo vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Cairo vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Cairo. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Cairo in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $96 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Cairo rentals

At Expedia, we put the best Cairo vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Cairo rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Cairo vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Cairo. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Cairo?

Yes, we give you a choice of vacation rentals close to popular local attractions in Cairo, or you can go with a more remote option if you're looking for relaxation. Cairo is known for its restaurants and entertainment choices. Make sure you have time to check out the riverfront while you're in the area.

What are some of the best vacation rentals in Cairo?

Quiet home on horse farm, halfway between Paducah & Wickliffe. Close to 60 & 286: Visitors like this Cairo vacation home rental. It is located in a rural location and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in Cairo?

Mississippi River and Ohio River Valley are a couple of lovely local spots to get outside and enjoy nature. Fort Defiance State Park and Ballard Wildlife Management Area are a couple of places you'll find in the larger area.

What’s a vacation rental in Cairo like?

Vacation rentals are privately owned properties you can stay in for several days or longer in Cairo. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy lobbies while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great choice for a family trip or a small group gathering.