$323 Cheap Flights from Detroit (DTW) to Gainesville (GNV)

View $323 flight on Fri, Sep 4, 2026Opens in a new window

Popular airlines from Detroit Metropolitan Wayne County Airport (DTW) to Gainesville Regional Airport (GNV)

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Cheap Flights from Detroit to Gainesville (DTW-GNV)

Prices were available within the past 7 days and start at $323 for one-way flights and $373 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Apr 7 - Wed, Apr 14
DTW
Detroit
GNV
Gainesville
$373 Roundtrip, found 20 hours ago
$373
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Wed, Apr 7 from Detroit to Gainesville, returning Wed, Apr 14, priced at $373 found 20 hours ago
Delta
Tue, Jun 30 - Tue, Jul 21
DTW
Detroit
GNV
Gainesville
$373 Roundtrip, found 4 hours ago
$373
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jun 30 from Detroit to Gainesville, returning Tue, Jul 21, priced at $373 found 4 hours ago
Delta
Sat, Aug 1 - Sat, Aug 15
DTW
Detroit
GNV
Gainesville
$406 Roundtrip, found 4 hours ago
$406
Roundtrip
found 4 hours ago
Select Delta flight, departing Sat, Aug 1 from Detroit to Gainesville, returning Sat, Aug 15, priced at $406 found 4 hours ago
American Airlines
Wed, Jul 1 - Tue, Jul 7
DTW
Detroit
GNV
Gainesville
$409 Roundtrip, found 4 hours ago
$409
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Jul 1 from Detroit to Gainesville, returning Tue, Jul 7, priced at $409 found 4 hours ago
Delta
Tue, Jun 30 - Mon, Jul 20
DTW
Detroit
GNV
Gainesville
$410 Roundtrip, found 4 hours ago
$410
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Jun 30 from Detroit to Gainesville, returning Mon, Jul 20, priced at $410 found 4 hours ago
Delta
Fri, Jul 10 - Tue, Jul 21
DTW
Detroit
GNV
Gainesville
$420 Roundtrip, found 4 hours ago
$420
Roundtrip
found 4 hours ago
Select Delta flight, departing Fri, Jul 10 from Detroit to Gainesville, returning Tue, Jul 21, priced at $420 found 4 hours ago
American Airlines
Fri, Jan 15 - Tue, Jan 19
DTW
Detroit
GNV
Gainesville
$422 Roundtrip, found 20 hours ago
$422
Roundtrip
found 20 hours ago
Select American Airlines flight, departing Fri, Jan 15 from Detroit to Gainesville, returning Tue, Jan 19, priced at $422 found 20 hours ago
American Airlines
Wed, Jul 1 - Wed, Jul 8
DTW
Detroit
GNV
Gainesville
$429 Roundtrip, found 4 hours ago
$429
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Wed, Jul 1 from Detroit to Gainesville, returning Wed, Jul 8, priced at $429 found 4 hours ago
Delta
Wed, Jan 20 - Wed, Jan 27
DTW
Detroit
GNV
Gainesville
$439 Roundtrip, found 20 hours ago
$439
Roundtrip
found 20 hours ago
Select Delta flight, departing Wed, Jan 20 from Detroit to Gainesville, returning Wed, Jan 27, priced at $439 found 20 hours ago
Delta
Sat, Aug 1 - Sun, Aug 16
DTW
Detroit
GNV
Gainesville
$443 Roundtrip, found 4 hours ago
$443
Roundtrip
found 4 hours ago
Select Delta flight, departing Sat, Aug 1 from Detroit to Gainesville, returning Sun, Aug 16, priced at $443 found 4 hours ago

Alternative airports near Gainesville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Gainesville Regional GNV. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $505
GNV
Gainesville Regional
CheapestClosest
Average driving time to city center10 min
Flights from $505

What you need to know for your flight from Detroit Metropolitan Wayne County to Gainesville Regional

Detroit (DTW) to Gainesville (GNV) at a glance

Discover a range of airlines offering flights from Detroit (DTW) to Gainesville (GNV) on this domestic short-haul route. Evaluate your choices among full-service carriers to identify the itinerary that aligns with your budget, schedule, and travel needs as you prepare to explore Gainesville's renowned attractions and neighborhoods. Here, you'll find essential information for flights from Detroit Metropolitan Wayne County Airport to Gainesville Regional Airport.

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 900 miles (1,450 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $115–$490, depending on seasonality and how far ahead you book

Flights from Detroit Metropolitan Wayne County Airport (DTW) to Gainesville Regional Airport (GNV)

Based on the latest traveler bookings, here are the top airlines favored for one-stop flights from Detroit to Gainesville. Travelers often opt for layovers at Hartsfield-Jackson Atlanta International Airport (ATL, approximately 1 hour and 15 minutes), Charlotte-Douglas International Airport (CLT, around 1 hour and 15 minutes), and Miami International Airport (MIA, about a 40-minute layover). This flexibility allows you to compare prices, total travel times, and cabin classes to find the most suitable itinerary.

  • American Airlines: This full-service airline provides one-stop travel, with one-way fares generally falling between $115 and $440. It represents about 54% of the flights on this route, featuring an in-flight duration of 3 hours and 30 minutes, and a total travel time of approximately 4 hours and 45 minutes, including layover time.
  • Delta: As another full-service option, Delta offers one-stop services with one-way fares that typically range from $150 to $720. It accounts for around 46% of departures on this route, providing an in-flight time of 3 hours and 30 minutes, with an overall journey time of about 4 hours and 45 minutes, factoring in the layover.

Travelers flying from Detroit to Gainesville can opt for an upgrade, with Delta providing first-class service on this route.

Best time to fly from Detroit (DTW) to Gainesville (GNV)

The most popular months for travelers flying from Detroit to Gainesville are February, April, and November, when peak temperatures in Gainesville reach up to 70.2°F in April. If you prefer quieter travel, consider September, the least busy time to visit with temperatures around 78.4°F and typically the lowest average one-way fare (around $170). Flight availability peaks in November, with approximately 10 flights per week, making it easier to find convenient departure times.

  • Cheapest time to fly: September usually offers good deals with average one-way fare around $170, roughly 41% cheaper than the yearly average.
  • Another budget-friendly time to fly: May typically offers an average one-way fare of around $171.
  • Most flight options: November has the highest number of flights from Detroit to Gainesville, with approximately 10 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January55.8°F (13.2°C)Average7$348
February60.1°F (15.6°C)High9$296
March64.2°F (17.9°C)Average8$393
April70.2°F (21.2°C)High8$304
May75.6°F (24.2°C)Average9$171
June80.1°F (26.7°C)Average9$313
July81.5°F (27.5°C)Low8$282
August81.5°F (27.5°C)Average8$359
September78.4°F (25.8°C)Low7$170
October72.0°F (22.2°C)Low9$265
November63.9°F (17.7°C)High10$286
December59.7°F (15.4°C)Average9$281

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Detroit (DTW) to Gainesville (GNV)

  • Detroit to Jacksonville (DTW-JAX): Jacksonville International Airport (JAX) lies approximately 66 miles from Gainesville Regional Airport (GNV). One-way economy tickets for this journey generally fall between $95 and $450, influenced by the time of year and how far in advance you book. The route is usually served by both non-stop and one-stop flights. Major airlines operating on this route include Delta and American Airlines. Additionally, first-class service is offered for those seeking a more premium experience.

How to find the best prices for flights from Detroit (DTW) to Gainesville (GNV)

Getting some of the best deals on flights from Detroit to Gainesville is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures between 5 am and 12 pm tend to offer lower prices and are also the most popular flight times. Additionally, flying on Wednesday not only provides cheaper prices but is also the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.* Find Gainesville hotel and flight deals.
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Gainesville Regional Airport from Detroit Metropolitan Wayne County Airport

Gainesville welcomes travelers from Detroit with a range of transport options based on price, convenience, and proximity. Here's how to reach Gainesville efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Gainesville, with options including free hotel shuttles and private rides, which can be arranged in advance with your hotel.
  • Car rental: Renting a car from Gainesville Regional Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Gainesville Regional Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Gainesville Regional Airport, Gainesville Downtown Station, a bus station, is located about 5.2 miles away by car, providing convenient access to public transportation for travelers heading into the city.

Frequently asked questions

How much does a flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) cost?
You can find cheap one-way flights from $323 and cheap return flights from $373 Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) with Expedia. One-way flights typically cost between $243 and $902, and return flights often range between $418 and $1474. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
The cheapest month to fly from DTW to GNV is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
Enter DTW to GNV and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Detroit (DTW) to Gainesville (GNV) with a layover in Ronald Reagan Washington National (DCA), starting from around $336 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
To find a cheap flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
The earliest flight from Detroit Metropolitan Wayne County (DTW) to Gainesville Regional (GNV) usually leaves at around 5:00 AM, operated by American Airlines. This seasonal service is active in May, giving you an early start to your day in Gainesville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
For flights from Detroit Metropolitan Wayne County Airport (DTW) to Gainesville Regional Airport (GNV), the most popular departure times are in the early morning, from 6am to 9am. About 39% of travelers prefer this time window. Many major carriers, including American Airlines and Delta Airlines, offer flights during this period. This timing is ideal as it allows you to start your day early and make the most of your time in Gainesville.
How long does it take to fly from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
A flight from DTW to GNV with a layover takes around 4 hours 30 minutes, with the route covering approximately 868 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
You can fly first class between DTW and GNV. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) flight with Expedia?
It's easy to earn miles on a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Gainesville from Detroit Metropolitan Wayne County (DTW)?
From Detroit Metropolitan Wayne County (DTW), you can fly into Gainesville Regional (GNV) to reach Gainesville. Some flights may connect through major hubs like O'Hare Intl. (ORD), Liberty Intl. (EWR), George Bush Intercontinental (IAH) before reaching Gainesville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) at the last minute?
Typically, booking a last minute flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) flight and hotel package?
Securing a Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) Gainesville Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional)?
If you booked your Detroit, MI (DTW-Detroit Metropolitan Wayne County) to Gainesville, FL (GNV-Gainesville Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Detroit Metropolitan Wayne County
Destination airport
Gainesville Regional
Airlines serving
American Airlines, Delta
Roundtrip price
$372
Distance
868 mi

Book with confidence

Detroit to Gainesville Flights

The cheapest times to fly from Detroit to Gainesville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Detroit to Gainesville are during the month of April. You can find some of the cheapest flights from Detroit to Gainesville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Detroit to Gainesville

Sunday is one of the best days to book for cheap flights from Detroit to Gainesville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Detroit to Gainesville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Detroit to Gainesville in 2026. You can also book with separate airlines for your outbound and return journeys, from $323 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Detroit to Gainesville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Detroit to Gainesville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Detroit to Gainesville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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