$268 Cheap Flights from Greenville (GSP) to Gainesville (GNV)

View $268 flight on Tue, Aug 11, 2026Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Gainesville Regional Airport (GNV)

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Cheap Flights from Greenville to Gainesville (GSP-GNV)

Prices were available within the past 7 days and start at $268 for one-way flights and $357 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Nov 12 - Tue, Nov 17
GSP
Greenville
GNV
Gainesville
$357 Roundtrip, found 2 days ago
$357
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 12 from Greenville to Gainesville, returning Tue, Nov 17, priced at $357 found 2 days ago
American Airlines
Thu, Jul 23 - Sun, Jul 26
GSP
Greenville
GNV
Gainesville
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select American Airlines flight, departing Thu, Jul 23 from Greenville to Gainesville, returning Sun, Jul 26, priced at $367 found 1 day ago
Delta
Sat, Jul 11 - Sat, Jul 18
GSP
Greenville
GNV
Gainesville
$377 Roundtrip, found 4 days ago
$377
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jul 11 from Greenville to Gainesville, returning Sat, Jul 18, priced at $377 found 4 days ago
Delta
Tue, Jun 30 - Tue, Jul 14
GSP
Greenville
GNV
Gainesville
$382 Roundtrip, found 4 days ago
$382
Roundtrip
found 4 days ago
Select Delta flight, departing Tue, Jun 30 from Greenville to Gainesville, returning Tue, Jul 14, priced at $382 found 4 days ago
Delta
Thu, Nov 12 - Tue, Nov 17
GSP
Greenville
GNV
Gainesville
$393 Roundtrip, found 2 days ago
$393
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Nov 12 from Greenville to Gainesville, returning Tue, Nov 17, priced at $393 found 2 days ago
Delta
Thu, Jul 23 - Sun, Jul 26
GSP
Greenville
GNV
Gainesville
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Jul 23 from Greenville to Gainesville, returning Sun, Jul 26, priced at $403 found 1 day ago
Delta
Sat, Jul 11 - Sat, Jul 18
GSP
Greenville
GNV
Gainesville
$407 Roundtrip, found 4 days ago
$407
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jul 11 from Greenville to Gainesville, returning Sat, Jul 18, priced at $407 found 4 days ago
Delta
Sat, Jul 11 - Sat, Jul 18
GSP
Greenville
GNV
Gainesville
$413 Roundtrip, found 4 days ago
$413
Roundtrip
found 4 days ago
Select Delta flight, departing Sat, Jul 11 from Greenville to Gainesville, returning Sat, Jul 18, priced at $413 found 4 days ago
American Airlines
Tue, Jun 30 - Tue, Jul 14
GSP
Greenville
GNV
Gainesville
$417 Roundtrip, found 4 days ago
$417
Roundtrip
found 4 days ago
Select American Airlines flight, departing Tue, Jun 30 from Greenville to Gainesville, returning Tue, Jul 14, priced at $417 found 4 days ago
American Airlines
Thu, Nov 12 - Tue, Nov 17
GSP
Greenville
GNV
Gainesville
$425 Roundtrip, found 2 days ago
$425
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Nov 12 from Greenville to Gainesville, returning Tue, Nov 17, priced at $425 found 2 days ago

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) cost?
You can find cheap one-way flights from $268 and cheap return flights from $357 Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) with Expedia. One-way flights generally range between $253 and $758, and roundtrip flights usually range from $422 to $1108. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The cheapest month to fly from GSP to GNV is November when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
Enter GSP to GNV and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from Greenville-Spartanburg Intl. (GSP) to Gainesville Regional (GNV) with a layover in Dallas/Fort Worth (DFW), starting from around $296 for a round-trip ticket. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The earliest flight from Greenville, SC (GSP) to Gainesville, FL (GNV) typically leaves at around 5:00 AM, operated by American Airlines. This seasonal service is active in November, allowing you to make the most of your day in Gainesville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The most popular departure times for flights from Greenville, SC (GSP) to Gainesville, FL (GNV) are in the early morning, from 6am to 9am. About 40% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United Airlines, operate flights during this window. This timing works well because it allows you to start your day early and maximize your time in Gainesville.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
Flights from GSP to GNV with one stop typically take around 4 hours, covering approximately 360 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
First class seats are offered on the GSP to GNV route with Delta Air Lines and American Airlines.
How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Gainesville from Greenville-Spartanburg Intl. (GSP)?
If you're planning to travel to Gainesville from Greenville-Spartanburg Intl. (GSP), you can fly into Gainesville Regional (GNV) Some flights may connect through major hubs like O'Hare Intl. (ORD), George Bush Intercontinental (IAH), Washington Dulles Intl. (IAD) before reaching Gainesville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) Gainesville Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
Gainesville Regional
Airlines serving
American Airlines, Delta
Roundtrip price
$356
Distance
359 mi

Book with confidence

Greenville to Gainesville Flights

The cheapest times to fly from Greenville to Gainesville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Gainesville are during the month of November. You can find some of the cheapest flights from Greenville to Gainesville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Gainesville

Sunday is one of the best days to book for cheap flights from Greenville to Gainesville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Gainesville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Gainesville in 2026. You can also book with separate airlines for your outbound and return journeys, from $268 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Gainesville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Gainesville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Greenville to Gainesville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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