$263 Cheap Flights from St. Louis (STL) to Gainesville (GNV)

View $263 flight on Sat, Sep 5, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Gainesville Regional Airport (GNV)

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Cheap Flights from St. Louis to Gainesville (STL-GNV)

Prices were available within the past 7 days and start at $263 for one-way flights and $373 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Sep 5 - Sat, Sep 12
STL
St. Louis
GNV
Gainesville
$373 Roundtrip, just found
$373
Roundtrip
just found
Select American Airlines flight, departing Sat, Sep 5 from St. Louis to Gainesville, returning Sat, Sep 12, priced at $373 just found
Delta
Sat, Sep 5 - Sat, Sep 12
STL
St. Louis
GNV
Gainesville
$373 Roundtrip, just found
$373
Roundtrip
just found
Select Delta flight, departing Sat, Sep 5 from St. Louis to Gainesville, returning Sat, Sep 12, priced at $373 just found
American Airlines
Wed, Jul 22 - Tue, Jul 28
STL
St. Louis
GNV
Gainesville
$385 Roundtrip, found 1 day ago
$385
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Jul 22 from St. Louis to Gainesville, returning Tue, Jul 28, priced at $385 found 1 day ago
Delta
Fri, Aug 7 - Sat, Aug 8
STL
St. Louis
GNV
Gainesville
$395 Roundtrip, found 7 hours ago
$395
Roundtrip
found 7 hours ago
Select Delta flight, departing Fri, Aug 7 from St. Louis to Gainesville, returning Sat, Aug 8, priced at $395 found 7 hours ago
Delta
Wed, Jul 22 - Tue, Jul 28
STL
St. Louis
GNV
Gainesville
$399 Roundtrip, found 1 day ago
$399
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jul 22 from St. Louis to Gainesville, returning Tue, Jul 28, priced at $399 found 1 day ago
Delta
Sat, Sep 5 - Sat, Sep 12
STL
St. Louis
GNV
Gainesville
$406 Roundtrip, just found
$406
Roundtrip
just found
Select Delta flight, departing Sat, Sep 5 from St. Louis to Gainesville, returning Sat, Sep 12, priced at $406 just found
American Airlines
Fri, Jul 17 - Tue, Jul 21
STL
St. Louis
GNV
Gainesville
$407 Roundtrip, found 5 days ago
$407
Roundtrip
found 5 days ago
Select American Airlines flight, departing Fri, Jul 17 from St. Louis to Gainesville, returning Tue, Jul 21, priced at $407 found 5 days ago
American Airlines
Sat, Sep 5 - Sat, Sep 12
STL
St. Louis
GNV
Gainesville
$408 Roundtrip, just found
$408
Roundtrip
just found
Select American Airlines flight, departing Sat, Sep 5 from St. Louis to Gainesville, returning Sat, Sep 12, priced at $408 just found
American Airlines
Fri, Oct 9 - Wed, Oct 14
STL
St. Louis
GNV
Gainesville
$410 Roundtrip, found 13 hours ago
$410
Roundtrip
found 13 hours ago
Select American Airlines flight, departing Fri, Oct 9 from St. Louis to Gainesville, returning Wed, Oct 14, priced at $410 found 13 hours ago
Delta
Sat, Sep 5 - Sat, Sep 12
STL
St. Louis
GNV
Gainesville
$412 Roundtrip, just found
$412
Roundtrip
just found
Select Delta flight, departing Sat, Sep 5 from St. Louis to Gainesville, returning Sat, Sep 12, priced at $412 just found

Alternative airports near Gainesville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Gainesville Regional GNV. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $408
GNV
Gainesville Regional
CheapestClosest
Average driving time to city center10 min
Flights from $408

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) cost?
You can find cheap one-way flights from $263 and cheap return flights from $373 St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) with Expedia. One-way flights generally range between $253 and $748, and roundtrip flights usually range from $460 to $1468. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
June is the cheapest month to fly from St. Louis (STL) to Gainesville (GNV), with average return fares around $394. This is about 18% lower than the average price throughout the year, as travel demand tends to dip during the early summer. Other affordable months to consider are May and August.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
Enter STL to GNV and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
American Airlines is one of the cheapest airlines offering connecting flights from St. Louis (STL) to Gainesville (GNV) with a layover in Ronald Reagan Washington National (DCA), starting from around $336. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
To find a cheap flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The ideal months to fly from St. Louis (STL) to Gainesville (GNV) are June and August. June is particularly appealing as it is both a popular month for travel and offers return flights at around $394. This means you can enjoy the summer weather while also finding good flight options.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The earliest flight from Lambert-St. Louis International Airport (STL) to Gainesville Regional Airport (GNV) usually departs at 5:00 AM, operated by American Airlines. An early departure like this can help you make the most of your time in Gainesville. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
The most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) are in the morning, from 6am to 9am. About 47% of passengers prefer this time window. Many major carriers, including Delta, American Airlines, and United Airlines, offer flights during this window. This timing works well because it allows you to arrive in Gainesville with plenty of time to enjoy your day.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
Flying from STL to GNV with a connection usually takes about 5 hours 20 minutes, traveling roughly 777 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
First class seats are offered on the STL to GNV route with Delta Air Lines and American Airlines.
How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Gainesville from Lambert-St. Louis Intl. (STL)?
From Lambert-St. Louis Intl. (STL), you can fly into Gainesville Regional (GNV) to reach Gainesville. Some flights may connect through major hubs like George Bush Intercontinental (IAH), O'Hare Intl. (ORD), Washington Dulles Intl. (IAD) before reaching Gainesville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) Gainesville Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional)?
If you booked your St. Louis, MO (STL-Lambert-St. Louis Intl.) to Gainesville, FL (GNV-Gainesville Regional) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Gainesville Regional
Airlines serving
American Airlines, Delta
Roundtrip price
$372
Distance
777 mi

Book with confidence

St. Louis to Gainesville Flights

The cheapest times to fly from St. Louis to Gainesville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Gainesville are during the month of September. You can find some of the cheapest flights from St. Louis to Gainesville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Gainesville

Sunday is one of the best days to book for cheap flights from St. Louis to Gainesville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Gainesville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Gainesville in 2026. You can also book with separate airlines for your outbound and return journeys, from $263 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Gainesville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Gainesville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Gainesville Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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