The Best Hotels Closest to Buffalo Museum of Science in Buffalo for 2026

A large mammoth skeleton in a museum with classical architecture.

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Our top choices for Buffalo Museum of Science hotels

A two-story building with a white exterior, a red door, and large windows.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

A hot tub with a wooden fence and a brick building in the background.

1. Buffalo Guesthouse

Allentown, 1.5 mi from Buffalo Museum of Science

Robert

$150 nightly

$172 total

Sep 6 - Sep 7

Total with taxes and fees

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

A traditional living room with a wooden floor, a sofa, a coffee table, and a fireplace.

A modern kitchen with a large window, stainless steel appliances, and wooden cabinetry.

A grand staircase with a decorative railing and a Christmas tree adorned with ornaments and ribbons.

2. Summer Street Guest House

Bryant, 1.8 mi from Buffalo Museum of Science

Anthony

$456 nightly

$523 total

Sep 7 - Sep 8

Total with taxes and fees

A hot tub area with a pool, outdoor seating, and large windows with a view of trees.

A breakfast area with a refrigerator stocked with snacks, a coffee machine, and a sign for Morning Medley Breakfast.

A reception area with a reception desk, two wooden chairs, and a vase of flowers.

A hotel room with a large bed, bedside lamps, a nightstand, and a wall with framed pictures.

3. Sleep Inn Amherst - Buffalo North near University

6.9 mi from Buffalo Museum of Science

Tariq

$118 nightly

$134 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with two beds, a desk, and a chair.

A Holiday Inn Express & Suites hotel entrance with a covered parking area and a clear sky.

An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

A hotel lobby with a reception desk, seating area, and a bar.

4. Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG

7.8 mi from Buffalo Museum of Science

HOSUNG

$118 nightly

$134 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel with a modern design, featuring a prominent 'La Quinta' sign, multiple windows, and a parking lot with several vehicles.

A hotel room with a large bed, two armchairs, a desk, and a lamp.

A modern restaurant with teal and yellow seating, a flat-screen TV, and a chandelier.

A hotel reception area with a large mural of a lighthouse, a reception desk, and a snack bar with shelves of snacks.

5. La Quinta Inn & Suites by Wyndham Buffalo Amherst

6.8 mi from Buffalo Museum of Science

Emilia

$96 nightly

$109 total

Sep 7 - Sep 8

Total with taxes and fees

A grand lobby with a reception desk, ornate decor, and a large clock.

A hotel lobby with a patterned carpet, ornate columns, and a staircase leading to an upper level.

A hotel room with a glass-enclosed shower, a marble bathroom vanity, a bed with a TV, a dining table, and a chair.

A lobby with a grand staircase, a chandelier, and a chessboard on a table.

6. Garden Place Hotel

7.9 mi from Buffalo Museum of Science

Raymond

$93 nightly

$106 total

Oct 1 - Oct 2

Total with taxes and fees

A reception area with a Pepsi refrigerator, a wooden counter, and seating arrangements including a blue sofa and orange chairs.

A Comfort Inn hotel with a modern design, featuring a prominent entrance, a covered walkway, and a well-maintained exterior.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A breakfast bar with a wooden finish, a fruit juice dispenser, a microwave, and a refrigerated display case.

7. Comfort Inn University

6.3 mi from Buffalo Museum of Science

Trevor

$95 nightly

$109 total

Sep 7 - Sep 8

Total with taxes and fees

An indoor swimming pool with clear water, lounge chairs, and a lifeguard stand.

A modern dining area with yellow chairs, wooden tables, and a central counter with a coffee machine.

A hotel room with a bed, a desk, a chair, a sofa, a small round table, and a TV mounted on the wall.

A modern hotel lobby with a blue accent wall, a reception desk, a sofa, a chair, and a coffee table.

8. Comfort Inn & Suites Buffalo Airport

6.2 mi from Buffalo Museum of Science

Sarah

$105 nightly

$123 total

Sep 30 - Oct 1

Total with taxes and fees

A row of white buildings with a central entrance, American flags, and a covered walkway.

A hotel room with a desk, a mirror, a lamp, and a small table with a tissue box and a brochure.

A hotel room with a large bed, a window with curtains, a chair, and a view of the outdoors.

A parking lot with two cars, a row of townhouses, and a clear sky.

9. CenterWay Hotel Buffalo North Near University

6.3 mi from Buffalo Museum of Science

Angie

$65 nightly

$74 total

Sep 20 - Sep 21

Total with taxes and fees

A hotel room with a bed, a desk with a television, a chair, and a window with curtains.

A reception area with a wooden reception desk, a cityscape painting, and a tiled floor.

A gym with treadmills, weight machines, and a mirrored wall.

A conference room with a large table surrounded by chairs, large windows with curtains, and a potted plant on the side.

10. Best Western Galleria Inn & Suites

3.3 mi from Buffalo Museum of Science

Stephanie

$83 nightly

$97 total

Sep 8 - Sep 9

Total with taxes and fees

A landscaped garden with a stone pathway, benches, and various flowering plants.

A hotel hallway with carpeted floors, orange walls, and doors on both sides.

A hotel reception area with a counter, a clock, and a view of the outside through large windows.

A motel with a large '6' sign, a brick building, and a parking lot.

11. Motel 6 Amherst, NY - Buffalo

6.1 mi from Buffalo Museum of Science

Felicidad

$70 nightly

$80 total

Sep 7 - Sep 8

Total with taxes and fees

A Red Roof Inn with a large building and a sign for HomeTowne Studios.

A modern building with a sign for 'Red Roof Inn' and 'HomeTown Studios & Suites'.

An indoor area with an ATM, a reception desk, and a seating area with chairs.

A modern bathroom with a granite countertop, a large mirror, a towel rack, and a hairdryer.

12. Red Roof Inn Buffalo - Niagara Airport

8 mi from Buffalo Museum of Science

"Good Stay, Convenient Location, and Fair Value Overall, I had a good experience at this hotel. The service was attentive, and the location made it convenient to get around and visit nearby places. The price was reasonable for the overall quality of the stay. For future travelers, I recommend comparing rates and confirming what is included; such as breakfast, parking, and any additional fees; before booking. If you value helpful service, a convenient location, and fair pricing, this hotel is a...

Efrain

$70 nightly

$79 total

Sep 7 - Sep 8

Total with taxes and fees

A hotel room with a bed, a bedside table with a phone, and a wall-mounted shelf with a red object.

A room with a bed, a desk, a chair, a TV, and a window.

A two-story building with a yellow facade, a red door, and a satellite dish on the roof.

A bathroom with a white sink, dark marble countertop, and tiled walls.

13. Budget Inn

5.6 mi from Buffalo Museum of Science

Vladimir

$79 nightly

$88 total

Sep 7 - Sep 8

Total with taxes and fees

A hotel with a row of parked cars in front, a landscaped garden area, and a building with a flat roof and multiple balconies.

A hotel room with three beds, each with a patterned bedspread, a nightstand with a lamp, and a headboard with a light fixture.

A hotel room with a large bed, two bedside tables, a headboard, and a patterned bedspread.

A bathroom with a toilet, a bathtub, and a shower curtain.

14. Scottish Inns Kenmore

5.5 mi from Buffalo Museum of Science

Christopher

$83 nightly

$92 total

Sep 23 - Sep 24

Total with taxes and fees

A hotel room with a wooden panel wall, two bedside lamps, a small wooden nightstand, and two white beds.

A Days Inn hotel with a modern design, featuring a central entrance, multiple windows, and a parking lot.

A motel with multiple floors, a parking lot with marked spaces, and a Burger King across the street.

15. Days Inn by Wyndham Tonawanda/Buffalo

5.4 mi from Buffalo Museum of Science

Maria

$94 nightly

$106 total

Sep 7 - Sep 8

Total with taxes and fees

A bathroom with a large bathtub, a small table with a chair, and a clock on a shelf.

A sign for University Manor Inn with a call-to-action for free WiFi.

A reception area with a light-colored wall, a butterfly artwork, a reception desk, and a door with a sign.

A bathroom with a large bathtub, a mirror, and a sink.

16. University Manor Inn

3.8 mi from Buffalo Museum of Science

lanlan

$132 nightly

$150 total

Sep 6 - Sep 7

Total with taxes and fees

A hotel room with two beds, each with green bedding and white pillows, a wooden headboard, a small table, and a window with curtains.

A motel with multiple rooms, a parking lot, and a grassy area with a child.

A kitchenette with a granite countertop, a microwave, and a television mounted above the counter.

A motel with a large parking lot and a building with a sign that reads "Motel Office".

17. Royal Inn

5.9 mi from Buffalo Museum of Science

Brian

$73 nightly

$82 total

Sep 8 - Sep 9

Total with taxes and fees

A multi-story hotel with a parking lot, a covered entrance, and a wheelchair-accessible sign.

A hotel lobby with a red wall, a welcome mat, two leather armchairs, and a black side table with a lamp.

A compact kitchen with white cabinets, a microwave, a stove, and a refrigerator.

A multi-story hotel with a beige facade, green window frames, and a parking lot in front.

18. Studio 6 Corporate Extended Stay Buffalo Amherst NY

6.8 mi from Buffalo Museum of Science

Lorena

$70 nightly

$80 total

Sep 13 - Sep 14

Total with taxes and fees

A hotel room with two beds, a desk, a television, and a window with an American flag.

A hotel registration area with a modern design, featuring a glass entrance and a parking lot in the foreground.

An ATM machine with a sign above it that reads "Got Cash Here!" next to a vending machine and a small bookshelf with magazines.

Two white front-loading washing machines in a corner with a tiled floor.

19. Fairbridge Inn Express Buffalo Airport Williamsville

8.3 mi from Buffalo Museum of Science

Vinujan

$55 nightly

$63 total

Oct 1 - Oct 2

Total with taxes and fees

A room with a patterned ceiling, a white door, a window with curtains, and a mounted television.

A hotel room with two beds, a nightstand, a lamp, and two framed pictures on the wall.

A motel with a sign reading "FALLS MOTEL" and a digital display showing "OPEN".

A bathroom with a toilet, sink, and shower area.

20. Blue Falls Motel

7.3 mi from Buffalo Museum of Science

Kathi

$75 nightly

$84 total

Sep 24 - Sep 25

Total with taxes and fees

View all properties

Compare popular hotels close to Buffalo Museum of Science

Property	Star rating	Guest rating
Buffalo Guesthouse	9.4 Exceptional 197 reviews	View
Summer Street Guest House	9.6 Exceptional 4 reviews	View
Sleep Inn Amherst - Buffalo North near University	8.8 Excellent 1,166 reviews	View
Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG	8.8 Excellent 726 reviews	View
La Quinta Inn & Suites by Wyndham Buffalo Amherst	8.4 Very Good 2,123 reviews	View

Top Buffalo Museum of Science Hotel Reviews

Wyndham Garden Buffalo Downtown

10/10 Excellent

"Lined my stay! Everyone was very kind!"

Hyatt Regency Buffalo / Hotel and Conference Center

10/10 Excellent

"Really great hotel in the middle Of downtown with awesome staff."

Spacious Historical Home by Parks, Shops, 4bd 2ba Save Weekly & monthly.

8/10 Good

"Great stay. Accommodated 5 of us very well. Great rental amenities."

Stunning Elmwood Village Lower

10/10 Excellent

"Recently renovated, very clean and comfortable stay. Great location, would be happy to stay again!"

Delightful dwelling

10/10 Excellent

"Exceptionally clean. All amenities included. Easy drive to Elmwood area. Quiet location over garage separate from house. Would stay longer next time."

Elmwood Village home

10/10 Excellent

"The apartment was super spacious, clean, and well-stocked. The place is in a nice neighborhood close to downtown. The communication with the host was easy. We would definitely stay here again!"

Nice and cozy house with king bed fenced yard

8/10 Good

"Was only there for over night stay. Comfortable"

Home away from home!

10/10 Excellent

"Very welcoming and helpful "

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Johnnie B. Wiley Sport Pavilion

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Paul Robeson Theater

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Broadway Market

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Koessler Athletic Center

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Montante Cultural Center

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Hellenic Orthodox Church of the Annunciation

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Frequently asked questions

What are the top-rated hotels near Buffalo Museum of Science?

For those looking to explore the Buffalo Museum of Science, there are top-rated hotels nearby that promise an exceptional stay.InnBuffalo off ElmwoodInnBuffalo off Elmwood is a charming Victorian hotel rated 10 by travelers, located just 2.6 miles from the Buffalo Museum of Science. Guests can enjoy unique amenities such as designer toiletries and a deep soaking bathtub. The hotel features self-parking and offers a free daily breakfast, along with a cozy fireplace and furnished balconies, making it a perfect retreat for those seeking comfort and style.Buffalo Harmony HouseBuffalo Harmony House, with a stellar review rating of 10 and a 4.5-star rating, is situated only 2.4 miles from the Buffalo Museum of Science. This romantic getaway features a private hot tub and beautiful gardens. Guests will appreciate the complimentary full breakfast, as well as the cozy fireplace and daily housekeeping services, all designed to provide a luxurious and relaxing experience.Carriage House Loft - King Bed and Garage ParkingThe Carriage House Loft offers a unique stay just 2.9 miles from the Buffalo Museum of Science, a perfect travelers' rating of 10. This historic hotel comes with a fully equipped kitchen, including an oven, dishwasher, and refrigerator, ideal for those who prefer a home-like experience. Guests enjoy the convenience of onsite garage parking and nearby shopping, making it a practical choice for extended stays.

How much is a hotel near Buffalo Museum of Science?

Staying near Buffalo Museum of Science is a treat, with plenty of hotels from $63 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a vacation during weekends or around public holidays.

What are the most popular family-friendly hotels near Buffalo Museum of Science?

For families looking for an enjoyable stay near Buffalo Museum of Science, several top-rated hotels offer family-friendly amenities and comfortable accommodations.Curtiss Hotel, Ascend Hotel CollectionCurtiss Hotel, Ascend Hotel Collection is a luxurious 5-star hotel located just 2.4 miles from Buffalo Museum of Science, an impressive travelers' rating of 9.2. This family-friendly hotel features connecting rooms, a travel crib, and children's meals at the on-site restaurant, ensuring a comfortable stay for families. Guests also enjoy amenities such as a full-service spa, hot springs, and complimentary breakfast, making it a perfect choice for relaxation after a day of exploring.Hilton Garden Inn Buffalo DowntownHilton Garden Inn Buffalo Downtown, rated 8.6 by travelers, is located just 2.5 miles from Buffalo Museum of Science. This 3-star hotel is perfect for families, offering amenities such as free cribs, connecting rooms, and a kids' menu at the restaurant. Guests can also enjoy the indoor pool and fitness facilities, along with convenient access to a grocery store, ensuring a pleasant and enjoyable stay for the entire family.Hampton Inn & Suites Buffalo DowntownHampton Inn & Suites Buffalo Downtown is a welcoming hotel situated 2.4 miles from Buffalo Museum of Science, with a solid review rating of 8.8. Families will appreciate the kitchenette in rooms, free cribs, and the option for rollaway beds, catering to their needs. The indoor accessible pool, buffet breakfast, and nearby parking further enhance the convenience and comfort for travelers, making it an ideal spot for family trips.

Are there any 5-star hotels near Buffalo Museum of Science?

Discover the top-rated 5-star hotels near Buffalo Museum of Science that promise an exquisite experience during your stay.Curtiss Hotel, Ascend Hotel CollectionCurtiss Hotel, Ascend Hotel Collection, rated 9.2 by travelers, is a luxurious 5-star hotel situated just 2.4 miles from Buffalo Museum of Science. Guests will appreciate the onsite spa offering a variety of treatments, including Swedish and deep tissue massages, alongside a range of hot springs to unwind after a day of exploration. The hotel features exquisite amenities such as Frette Italian sheets, a rooftop terrace, and complimentary breakfast options, ensuring a comfortable and indulgent stay.

Which hotels near Buffalo Museum of Science offer the best views?

Discover the top-rated hotels near Buffalo Museum of Science that offer stunning views and a memorable stay in Buffalo, New York.Buffalo Marriott at LECOM HARBORCENTERBuffalo Marriott at LECOM HARBORCENTER is a 3.5-star hotel located just 3.0 miles from the Buffalo Museum of Science, with an impressive review rating of 9.4. This waterfront hotel features stunning lake views that travelers can enjoy from various rooms and common areas. The hotel amenities include convenient valet parking, a fitness center, and daily housekeeping. With suites available and a snack bar on-site, it caters to both relaxation and convenience for travelers.The Richardson HotelThe Richardson Hotel, rated 9.0 by travelers, is a charming 3.5-star option located 3.5 miles from the Buffalo Museum of Science. Nestled in a historical district, this hotel offers a picturesque resort view and a serene garden for travelers to unwind. Key amenities include a 24-hour fitness facility, daily housekeeping, and self-parking, ensuring a comfortable stay. With its unique blend of history and modern comforts, it presents a delightful experience for those exploring Buffalo.

What are the best affordable hotels near Buffalo Museum of Science?

Discover the best affordable hotels near Buffalo Museum of Science, perfect for family-friendly stays and budget-conscious travelers.InnBuffalo off ElmwoodInnBuffalo off Elmwood, just 2.6 miles from Buffalo Museum of Science, is a charming Victorian hotel with a perfect travelers' rating of 10. This delightful stay offers complimentary breakfast daily, free WiFi, and a relaxing atmosphere with designer toiletries. Guests can enjoy additional amenities like a billiards table, yoga classes onsite, and the option for early check-in, making it an ideal choice for families seeking comfort and convenience.Carriage House Loft - King Bed and Garage ParkingThe Carriage House Loft - King Bed and Garage Parking is located 2.9 miles from Buffalo Museum of Science and is rated 10 by travelers. This historic loft features a fully equipped kitchen with a dishwasher and oven, perfect for families wanting to prepare their own meals. Guests also appreciate the convenience of onsite garage parking and nearby duty-free shopping, ensuring a comfortable and enjoyable stay.Summer Street Guest HouseSummer Street Guest House, positioned just 2.2 miles from Buffalo Museum of Science, boasts a strong travelers' rating of 10 and a 3-star designation. This traveler house offers essential amenities such as free WiFi and self-parking, making it a practical choice for families. Guests can unwind in the patio area or make use of the in-room kitchen facilities, creating a cozy home-away-from-home atmosphere.

Are there any hotels with pools close to Buffalo Museum of Science?

Looking for top-rated hotels with pools near Buffalo Museum of Science? Here are some excellent options that offer both relaxation and family-friendly amenities.Quality Inn Near Walden Galleria MallQuality Inn Near Walden Galleria Mall is a welcoming choice just 4.6 miles from Buffalo Museum of Science, featuring an indoor pool accessible for all travelers. Rated 8.0 by travelers, this hotel provides family-friendly amenities such as free cribs and daily continental breakfast. Guests can also enjoy free parking and a fitness center, making it a convenient stay for families.M Hotel BuffaloM Hotel Buffalo is situated 4.6 miles from Buffalo Museum of Science and holds a 3.5-star rating with a review rating of 7.4. This hotel features an indoor pool that is accessible for all travelers. Families will appreciate the free breakfast and on-site shopping mall, along with free parking and a scheduled airport shuttle service.Aloft Buffalo DowntownAloft Buffalo Downtown, located only 2.1 miles from Buffalo Museum of Science, is a stylish 3-star hotel an inviting indoor pool. With a review rating of 8.2, it offers features such as free breakfast and a 24-hour fitness center. Guests can also enjoy accessibility options, a billiards table, and evening entertainment, providing a vibrant atmosphere for families.

What are the best pet-friendly hotels near Buffalo Museum of Science?

Finding the perfect pet-friendly stay near Buffalo Museum of Science is easy with these top-rated options that welcome your furry friends.Home2 Suites by Hilton Buffalo Airport / Galleria MallHome2 Suites by Hilton Buffalo Airport / Galleria Mall is a 3-star hotel located just 4.8 miles from Buffalo Museum of Science, featuring a great traveler rating score of 9.0. This hotel is ideal for travelers with pets, offering pet-friendly amenities including food and water bowls and a welcoming atmosphere for dogs and cats. Guests can enjoy a range of amenities such as a free buffet breakfast, an indoor pool, and a fitness center, ensuring a comfortable and enjoyable stay.Hampton Inn & Suites Buffalo DowntownHampton Inn & Suites Buffalo Downtown is a comfortable option located just 2.4 miles from Buffalo Museum of Science, with an impressive review rating of 8.8. This pet-friendly hotel welcomes dogs and cats, providing food and water bowls for their convenience. Guests can enjoy amenities such as a free buffet breakfast, an indoor pool, and a rooftop garden, perfect for relaxation after a day of exploring.Aloft Buffalo DowntownAloft Buffalo Downtown is a stylish 3-star hotel situated only 2.1 miles from Buffalo Museum of Science, with a solid review rating of 8.2. This pet-friendly hotel allows pets in-room and offers complimentary amenities like food and water bowls. Guests can take advantage of the indoor pool, 24-hour fitness facilities, and a vibrant atmosphere with evening entertainment, making it a great choice for both travelers and their furry companions.

Can I book a fully refundable hotel close to Buffalo Museum of Science?

Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Buffalo Museum of Science", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore deals with free cancellation options on Expedia.

Find hotels near Buffalo Museum of Science, Buffalo from $63

Upfront pricing

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Buffalo Museum of Science hotels

1. Buffalo Guesthouse

2. Summer Street Guest House

3. Sleep Inn Amherst - Buffalo North near University

4. Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG

5. La Quinta Inn & Suites by Wyndham Buffalo Amherst

6. Garden Place Hotel

7. Comfort Inn University

8. Comfort Inn & Suites Buffalo Airport

9. CenterWay Hotel Buffalo North Near University

10. Best Western Galleria Inn & Suites

11. Motel 6 Amherst, NY - Buffalo

12. Red Roof Inn Buffalo - Niagara Airport

13. Budget Inn

14. Scottish Inns Kenmore

15. Days Inn by Wyndham Tonawanda/Buffalo

16. University Manor Inn

17. Royal Inn

18. Studio 6 Corporate Extended Stay Buffalo Amherst NY

19. Fairbridge Inn Express Buffalo Airport Williamsville

20. Blue Falls Motel

Compare popular hotels close to Buffalo Museum of Science

Top Buffalo Museum of Science Hotel Reviews

Wyndham Garden Buffalo Downtown

Hyatt Regency Buffalo / Hotel and Conference Center

Spacious Historical Home by Parks, Shops, 4bd 2ba Save Weekly & monthly.

Stunning Elmwood Village Lower

Delightful dwelling

Elmwood Village home

Nice and cozy house with king bed fenced yard

Home away from home!

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

Johnnie B. Wiley Sport Pavilion

Paul Robeson Theater

African American Cultural Center

Broadway Market

Koessler Athletic Center

Montante Cultural Center

Hellenic Orthodox Church of the Annunciation

Frequently asked questions

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