Find Business Hotels in South Loop, IL

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Our top choices for South Loop business-friendly hotels

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
Downtown Chicago
8.8 out of 10, Excellent, (1748)
"Clean and staff was courteous. "
United States
HANNAH
$71 nightly
The price is $84
Jan 5 - Jan 6, 2026
Total with taxes and fees
Hilton Garden Inn Chicago Downtown South Loop

Hilton Chicago

Hilton Chicago
4.0 star property
Downtown Chicago
8.4 out of 10, Very Good, (2366)
"We had a great stay and will be back again."
United States
Amber
$114 nightly
The price is $134
Dec 21 - Dec 22
Total with taxes and fees
Hilton Chicago

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
Downtown Chicago
8.0 out of 10, Very Good, (9657)
"Great stay comfortable bed and great location!"
United States
Kimberly Noel
$95 nightly
The price is $111
Dec 18 - Dec 19
Total with taxes and fees
Congress Plaza Hotel

Homewood Suites by Hilton Chicago Downtown South Loop

Homewood Suites by Hilton Chicago Downtown South Loop
3.0 star property
Downtown Chicago
8.8 out of 10, Excellent, (2128)
"Very nice place"
United States
Salman
$79 nightly
The price is $93
Jan 5 - Jan 6, 2026
Total with taxes and fees
Homewood Suites by Hilton Chicago Downtown South Loop

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel
4.0 star property
Downtown Chicago
9.6 out of 10, Exceptional, (1114)
"Great hotel for price and location Everything clean and a huge room "
United States
James
$95 nightly
The price is $112
Jan 4 - Jan 5, 2026
Total with taxes and fees
Bluegreen Vacations Hotel Blake, an Ascend Collection Hotel

Le Méridien Essex Chicago

Le Méridien Essex Chicago
4.0 star property
Downtown Chicago
8.6 out of 10, Excellent, (1000)
"Great stay for quick weekend trip "
United States
Natali
$102 nightly
The price is $120
Dec 22 - Dec 23
Total with taxes and fees
Le Méridien Essex Chicago

Sentral Michigan Avenue

Sentral Michigan Avenue
4.0 star property
Downtown Chicago
9.2 out of 10, Wonderful, (1005)
"Beautiful view, and a very nice condo. "
United States
Tiffanie
$143 nightly
The price is $168
Dec 21 - Dec 22
Total with taxes and fees
Sentral Michigan Avenue

The Blackstone, Autograph Collection

The Blackstone, Autograph Collection
4.0 star property
Downtown Chicago
9.0 out of 10, Wonderful, (1000)
"Great staff, beds and pillows very comfortable "
United States
Marty
$152 nightly
The price is $179
Dec 21 - Dec 22
Total with taxes and fees
The Blackstone, Autograph Collection

Hampton Inn Chicago McCormick Place

Hampton Inn Chicago McCormick Place
3.0 star property
Near South Side
9.0 out of 10, Wonderful, (1002)
"Very nice hotel "
United States
Lloyd
$77 nightly
The price is $90
Jan 10 - Jan 11, 2026
Total with taxes and fees
Hampton Inn Chicago McCormick Place

Home2 Suites by Hilton Chicago McCormick Place

Home2 Suites by Hilton Chicago McCormick Place
3.0 star property
Near South Side
9.2 out of 10, Wonderful, (726)
"Location, very spacious rooms, great breakfast!!! Excellent customer service!!! Will be staying there again. "
United States
Bianca
$71 nightly
The price is $84
Jan 2 - Jan 3, 2026
Total with taxes and fees
Home2 Suites by Hilton Chicago McCormick Place
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top South Loop Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in South Loop with Expedia?
With conveniences like meeting rooms, 24-hour room service and on-site cafés, our business-friendly accommodations come with everything you'll need to settle that big contract — and then relax in the comfort of your room. Enter your destination and preferred travel dates and Expedia will help you do the rest.
How can I find cheap business-friendly hotels in South Loop?
When work takes you to South Loop, our "business friendly" filter will help you find the right hotel. From dependable WiFi to concierge services and conference spaces, they have the amenities you need for a comfortable and productive stay. Another tip? Refine your search by your budget and preferred star rating to see the cheapest accommodations.

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