De Soto Vacation Rentals from $89: Search Short-Term Rentals

Q: What are some of the best vacation home rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio! : Visitors like this De Soto vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

Check prices for these dates

In two weeks

In two months

In three months

In four months

Our top choices for De Soto vacation rentals

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto

Janna B.

$265 nightly

Jul 12 - Jul 13

Total with taxes and fees

Coeur de la Crème Suite at Baetje Farms

Bloomsdale

Barbara

$145 nightly

Jul 1 - Jul 2

Total with taxes and fees

Vallee Suite at Baetje Farms

Bloomsdale

Heather

$140 nightly

Jul 1 - Jul 2

Total with taxes and fees

1 bedroom, desk, iron/ironing board, WiFi

Tiny Houses of French Village Tranquil & Relaxing

French Village

Sherri G.

$310 nightly

Jul 1 - Jul 2

Total with taxes and fees

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

Kenzia

$133 nightly

Jul 29 - Jul 30

Total with taxes and fees

Tiny Houses of French Village

French Village

Chris

$347 nightly

Jul 1 - Jul 2

Total with taxes and fees

Peter Ray House

Maeystown

PATRICK E.

$211 nightly

Jul 1 - Jul 2

Total with taxes and fees

RUSTIC RETREAT Cozy 2 Bed 1.5 Bath Home, in Rural Farmington, Wooded Outdoor.

Farmington

$169 nightly

Jul 3 - Jul 4

Total with taxes and fees

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Top De Soto Hotel Reviews

Comfort Inn Festus - St Louis South

8/10 Good

"The room was very nice,breakfast was good. We had a water overflow problem and the night shift never came to help. We had to clean it up ourselves. Morning checkin was good but other staff not so much GOOD FOR THE PRICE"

Baymont by Wyndham Festus

8/10 Good

"This property clearly was once a beautiful conference facility with a pool, large conference area that includes a big indoor fountain, lots of rooms and parking, etc. However, as what often happens in the hotel industry, this one has deteriorated over time. It's clear that the staff is doing the best with what they have to offer. The room was clean; beds comfortable. The room was clean but lots of little things needed maintenance.....BUT nothing that would make your stay awful....just things I notice, having worked in hotel sales & management. Example: The faucet's size didn't fit the opening in the sink, so the faucet was sort of loose. Drapes were missing some curtain rings and so we had to sort of 'arrange' the curtains around a chair to keep the light out---a privacy issue but one not impossible to resolve. We stayed one night on our way to our destination and one night coming back. The second night clearly someone had smoked in the room (NOT allowed!) and housekeeping had shampooed the carpet. I'm sure it was to help alleviate the odor but sadly, carpets were not dry yet. The humidity in the room was pretty high but we resolved it by putting on the heat while we went to dinner and then the AC. Breakfast offerings were plenty and hours for breakfast were quite ample. As of this review (6/29/2026) I'd say for the price, it's a good value. I really feel bad to see properties go downhill when clearly there once were a beautiful property."

Crown Pointe Lodge, BW Signature Collection

8/10 Good

"Overall this is a fine hotel. The staff was super friendly, the room was pretty clean and the property was accessible to the highway. Some observations: the drain was draining super slowly. This hotel is adjacent to a golf course so they are overrun by middle aged golfers who like to party once they are done for the day. They drink, smoke, and make plenty of noise. I stayed on the first floor near the lobby and that was a mistake on my part. To sum up, great staff, fairly clean, decent breakfast."

Super 8 by Wyndham Farmington

8/10 Good

"Appreciated the outdoor pool after a hot day of hiking and outdoor activity. Also really appreciated that front desk staff immediately put me in a different but identical room after I walked into the first room, tried to close the shade and the cord totally broke. I was very comfortable, had all my needs met and the price was market value"

Find out more about De Soto

Everything you need to know about De Soto vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the De Soto vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect De Soto vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

De Soto vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in De Soto. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit De Soto in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $89 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on De Soto rentals

At Expedia, we put the best De Soto vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top De Soto rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream De Soto vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around De Soto. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Things to do in St. Louis

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, there are vacation rentals close to the most popular attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay. De Soto is known for its restaurants.

What are some of the best vacation home rentals that De Soto has to offer?

Gated 35-Acre De Soto Estate: Pool, Lake & Patio!: Visitors like this De Soto vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games.

What’s there to see and do in De Soto?

Sunrise Lake Beach and Big River are a couple of lovely local spots to get outside and enjoy nature. While here, Washington State Park and Redfield's Flea Market are other places worth a visit.

What’s a vacation rental in De Soto like?

Vacation rentals are private properties you can stay in for several days or longer in De Soto. Vacation rentals offer amenities such as kitchens and laundry facilities so you'll have everything you want. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family getaway.

De Soto Vacation Rentals

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Check prices for these dates

Our top choices for De Soto vacation rentals

82 Acre Hobby Farm with Lincoln Log Cabin

Coeur de la Crème Suite at Baetje Farms

Vallee Suite at Baetje Farms

Tiny Houses of French Village Tranquil & Relaxing

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Tiny Houses of French Village

Peter Ray House

RUSTIC RETREAT Cozy 2 Bed 1.5 Bath Home, in Rural Farmington, Wooded Outdoor.

Cozy Three bedroom home in Central Farmington

King Bed, game room minutes away from downtown, golf courses + BIG back yard

Cozy 1-bedroom cabin in wonderful Leadwood with AC

Your home away from home in downtown, historic Farmington!

Upstairs 2 bedroom Private Apt Off I- 55 in Pevely

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC w/ room for your horses

Clifford's Country Cottage

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Peaceful, cozy 1 bdrm home w hot tub & fire pit in the quiet countryside.

Beautiful historical two story stone farmhouse

Homestead Hideaway + Hot Tub

Cozy Serene home off 55 Queen Bed Smart TVs Wi-Fi

Find vacation rentals that suit your style

Top De Soto Hotel Reviews

Comfort Inn Festus - St Louis South

Find out more about De Soto

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