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Our top choices for Commerce hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,001 reviews)
"Great travel hotel from Texas to Chicago."
United States
Sally
$111 nightly
The price is $128
May 25 - May 26
Total with taxes and fees
Drury Inn & Suites Sikeston, MO

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
$74 nightly
The price is $82
May 17 - May 18
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
"We found this property to be everything someone would hope for in an overnight stay away from home."
United States
Richard
$100 nightly
The price is $113
May 21 - May 22
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (125 reviews)
"This is a clean, quiet, well designed hotel."
United States
Kendra
$94 nightly
The price is $107
Jun 14 - Jun 15
Total with taxes and fees
Tru By Hilton Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (184 reviews)
"Nice room, good breakfast "
United States
KENNETH
$93 nightly
The price is $105
May 28 - May 29
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (571 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
United States
Audra
$120 nightly
The price is $135
May 19 - May 20
Total with taxes and fees
The Riverview

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean and comfortable room for a good price."
United States
Mary
$88 nightly
The price is $99
May 31 - Jun 1
Total with taxes and fees
Drury Inn & Suites Cape Girardeau

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Excellent layover stay"
United States
Wesley H.
$70 nightly
The price is $79
May 25 - May 26
Total with taxes and fees
Pear Tree Inn Cape Girardeau West

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
"We love staying at this inn. It truly feels like we’re in a friend’s beautifully appointed home. We’ll be back here again for certain. "
United States
Elsa
$138 nightly
The price is $155
May 17 - May 18
Total with taxes and fees
Rockwood Inn

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (765 reviews)
"Nice hotel"
United States
Jeff
$93 nightly
The price is $100
May 19 - May 20
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (813 reviews)
"We enjoyed our stay"
United States
Wanda
$106 nightly
The price is $119
May 24 - May 25
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (742 reviews)
"It was good, but a noticeable hole in the wall above the toilet paper."
United States
Martin
$67 nightly
The price is $75
May 24 - May 25
Total with taxes and fees
Quality Inn Cape Girardeau North

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
$72 nightly
The price is $79
May 17 - May 18
Total with taxes and fees
Eagle Inn Charleston

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (285 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
$71 nightly
The price is $79
Jun 6 - Jun 7
Total with taxes and fees
Quality Inn Cairo I-57

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (634 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
$60 nightly
The price is $66
Jun 7 - Jun 8
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Room was very clean. Breakfast was good with several options. Would recommend staying here."
United States
Linda
$110 nightly
The price is $124
May 31 - Jun 1
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (506 reviews)
"Great place! "
United States
Michelle
$125 nightly
The price is $142
May 29 - May 30
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (934 reviews)
"It was a great place to stay. Convenient to go any where y"
United States
Marilyn
$74 nightly
The price is $89
May 25 - May 26
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (766 reviews)
"Beds felt amazing. My family and I had a great time"
United States
Gary
$92 nightly
The price is $100
May 21 - May 22
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (138 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
United States
Sheryl
$54 nightly
The price is $61
May 18 - May 19
Total with taxes and fees
Country Yard Inn and Suite
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Top Commerce Hotel Reviews

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Frequently asked questions

What is the best area to stay in Commerce?
For most visitors, the best area to stay in Commerce is near the downtown area, particularly around the main square.

This area is the heart of Commerce, offering easy access to local shops, eateries, and community events. You'll find a relaxed pace here, with many of the town's historical buildings and local businesses concentrated within a few blocks of the central square. It's an ideal spot for couples looking for a quiet getaway.

Solo travelers will also find this area convenient due to its central location and the availability of local amenities within walking distance.
When is the best time to go to Commerce?
The best time to visit Commerce is during the spring or fall when the weather is pleasant and comfortable.

Spring, particularly from April to May, brings mild temperatures and blooming flora, making it ideal for outdoor activities like exploring the local parks or enjoying a stroll along the Mississippi River. The humidity is generally lower during these months, which adds to the comfort. This period is great for couples who enjoy scenic walks and pleasant weather without the summer crowds.

Fall, from September to October, also offers agreeable temperatures and beautiful autumn foliage, especially along the riverbanks. The air is crisp, and it's a good time for those who appreciate cooler weather for sightseeing or attending local events.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Commerce.
How can I save on a Commerce hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Commerce hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Commerce hotel?
Prices for hotels in Commerce often vary, but you can find a great deal from $61 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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