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Our top choices for Commerce hotels

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19 reviews)
"My stay was cozy, warm and inviting, and absolutely wonderful shower. I will definitely be returning! "
United States
Kim
$165 nightly
The price is $186
Jan 18 - Jan 19
Total with taxes and fees
Rockwood Inn

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
Cape Girardeau
6.0 out of 10, (208 reviews)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
$57 nightly
The price is $64
Jan 18 - Jan 19
Total with taxes and fees
Town House Inn Cape Giradreau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"Awesome stay!"
United States
Breckin
$90 nightly
The price is $102
Jan 21 - Jan 22
Total with taxes and fees
Drury Inn & Suites Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (105 reviews)
"It was a nice stay"
United States
Douglas
$89 nightly
The price is $102
Jan 28 - Jan 29
Total with taxes and fees
Tru By Hilton Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (890 reviews)
"Room was clean and spacious."
United States
George
$78 nightly
The price is $93
Feb 8 - Feb 9
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (787 reviews)
"Excellent stay"
United States
Christina
$106 nightly
The price is $119
Jan 22 - Jan 23
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (150 reviews)
"Great hotel - super clean, fast check-in, convenient, etc. We’ll definitely stay here again. "
United States
Richard
$88 nightly
The price is $99
Jan 25 - Jan 26
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
$91 nightly
The price is $103
Jan 25 - Jan 26
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (490 reviews)
" Excellent stay. Will come again"
United States
joydeep
$105 nightly
The price is $119
Jan 19 - Jan 20
Total with taxes and fees
The Riverview

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
$71 nightly
The price is $80
Jan 21 - Jan 22
Total with taxes and fees
Pear Tree Inn Cape Girardeau West

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (479 reviews)
"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
$125 nightly
The price is $142
Jan 25 - Jan 26
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (691 reviews)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
$58 nightly
The price is $65
Jan 22 - Jan 23
Total with taxes and fees
Quality Inn Cape Girardeau North

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
"Great place "
United States
Kelly
$90 nightly
The price is $102
Jan 21 - Jan 22
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (687 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
$80 nightly
The price is $86
Jan 25 - Jan 26
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,002 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
United States
Nicole
$94 nightly
The price is $108
Jan 21 - Jan 22
Total with taxes and fees
Drury Inn & Suites Sikeston, MO

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (740 reviews)
"Clean and comfortable every time. This is a “go to” hotel "
United States
Jacqulyn
$80 nightly
The price is $86
Jan 25 - Jan 26
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (121 reviews)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
$68 nightly
The price is $77
Jan 17 - Jan 18
Total with taxes and fees
Country Yard Inn and Suite

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (620 reviews)
"Staff was great! Room was nice. "
United States
Lana
$62 nightly
The price is $69
Jan 17 - Jan 18
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (275 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
$71 nightly
The price is $79
Jan 24 - Jan 25
Total with taxes and fees
Quality Inn Cairo I-57

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Staff great. "
United States
Nancy
$114 nightly
The price is $129
Jan 18 - Jan 19
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
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Top Commerce Hotel Reviews

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Hotels in Commerce with star-rating

Frequently asked questions

What is the best area to stay in Commerce?
For most visitors, the best area to stay in Commerce is near the downtown area, particularly around the main square.

This area is the heart of Commerce, offering easy access to local shops, eateries, and community events. You'll find a relaxed pace here, with many of the town's historical buildings and local businesses concentrated within a few blocks of the central square. It's an ideal spot for couples looking for a quiet getaway.

Solo travelers will also find this area convenient due to its central location and the availability of local amenities within walking distance.
When is the best time to go to Commerce?
The best time to visit Commerce is during the spring or fall when the weather is pleasant and comfortable.

Spring, particularly from April to May, brings mild temperatures and blooming flora, making it ideal for outdoor activities like exploring the local parks or enjoying a stroll along the Mississippi River. The humidity is generally lower during these months, which adds to the comfort. This period is great for couples who enjoy scenic walks and pleasant weather without the summer crowds.

Fall, from September to October, also offers agreeable temperatures and beautiful autumn foliage, especially along the riverbanks. The air is crisp, and it's a good time for those who appreciate cooler weather for sightseeing or attending local events.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Commerce.
How can I save on a Commerce hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Commerce hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Commerce hotel?
Prices for hotels in Commerce often vary, but you can find a great deal from $64 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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