Title: 20 Best B&B in Mesilla, NM - Bed and Breakfast from $57 | Expedia.com [Mesilla Travel Guide](https://expedia.com/Mesilla.dx132684)[Hotels in Mesilla](https://expedia.com/Mesilla-Hotels.d132684.Travel-Guide-Hotels)[Vacation Rentals in Mesilla](https://expedia.com/Mesilla-Vacation-Rentals.d132684.Travel-Guide-VacationRentals)[Flights to Mesilla](https://expedia.com/Cheap-Flights-To-Mesilla.d132684.Travel-Guide-Flights)[Car Rentals in Mesilla](https://expedia.com/Car-Rentals-In-Mesilla.d132684.Car-Rental-Guide)[Mesilla Vacation Packages](https://expedia.com/Mesilla.d132684.Destination-Travel-Guides) ![Red chile doorway Mesilla NM](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/132684/621c4b20-e7ee-452c-9495-0ec62a9d9908.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-04-24&endDate=2026-04-26&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-05-08&endDate=2026-05-10&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=132684&startDate=2026-06-05&endDate=2026-06-07&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in Mesilla ![Property grounds](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/71d7ce53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/6c9ad3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/cbe8afa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, DVD player, stereo](https://images.trvl-media.com/lodging/34000000/33740000/33734400/33734305/7ff2efb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian [](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information) Mesilla 10/10 Exceptional (82 reviews) "Very cozy and walking distance to shops and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miriam P. $201 nightly $226 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Mesilla-Hotels-Charming-Casita-In-Historic-Town-Of-Mesilla.h33734305.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/dec3042f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerobics facility](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/21207c1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/159896f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/f6627f8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Las Cruces I-10 [](https://www.expedia.com/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) Las Cruces 8.8/10 Excellent (1,001 reviews) "I enjoyed the pool and the breakfast was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana $114 nightly $132 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/4e26c2df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/89306788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/abb98945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 KING BED – NON-SMOKING | Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/a0c41c28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) Las Cruces 8.2/10 Very Good (1,418 reviews) "Good breakfast with clean room and helpful staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana $48 nightly $57 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/0b5e48d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/0464c626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/67719f59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Encanto de Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) Las Cruces 9.0/10 Wonderful (1,676 reviews) "A wonderful hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julian $138 nightly $158 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/f396e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/a357e7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/5e2c2e31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/97000000/96020000/96019000/96018978/c70868a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southwest Gem just minutes from White Sands National Park [](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information) Las Cruces 10/10 Exceptional (28 reviews) "kitchen fully equipped, pet friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard $253 nightly $269 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Southwest-Gem-Just-Minutes-From-White-Sands-National-Park.h96018978.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/b11f6a5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/b3e95919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/d91a3a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93680000/93674700/93674654/78146abc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tuscan Villa Outdoor Living, Jacuzzi & Gym [](https://www.expedia.com/Las-Cruces-Hotels-Tuscan-Villa-Outdoor-Living.h93674654.Hotel-Information) Las Cruces 9.4/10 Exceptional (18 reviews) "Beautiful house and would stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alethea S. $259 nightly $281 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Tuscan-Villa-Outdoor-Living.h93674654.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/bf624d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/539e32d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/a8b4113b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/117000000/116940000/116934400/116934309/e36b9650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information) Las Cruces 9.8/10 Exceptional (7 reviews) "I was truly impressed with my rental. It was extremely clean, quiet, comfortable and pleasant. The price was reasonable and we enjoyed it tremendously! Thank you John and Erica!!! My son enjoyed the popcorn. Hope to be renting this again soon!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert M. $136 nightly $148 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Charming-1-Bedroom-House-With-WiFi.h116934309.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/bc0a9d00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/1aa64a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/ccb4ff70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119930000/119923800/119923794/02adc68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Cruces Home w/ Fenced Yard: Recently Remodeled [](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) Las Cruces 10/10 Exceptional (1 review) "The host was thoughful. He provided all the information we needed and responded our questions really quickly. The house was clean and very well organized. This house had the best view at night. We will definitely visit again when we go Santa fe. 😊 " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nam $223 nightly $256 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Home-W-Fenced-Yard-Recently-Remodeled.h119923794.Hotel-Information) ![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/c3e0eeb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/2137413f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/cb3ffc47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/96000000/95420000/95418300/95418216/8cbc52c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Casita/Suite No cleaning fee. [](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information) Las Cruces 9.6/10 Exceptional (31 reviews) "Comfortable, nice suite; Was a short overnight stay. Would stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Susie S. $123 nightly $133 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-New-CasitaSuite-No-Cleaning-Fee.h95418216.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/46263956.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/affa980e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/68a7ba44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/0bffe062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) Las Cruces 9.4/10 Exceptional (1,013 reviews) "Everything was amazing the staff was amazing. We had a great and comfortable stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saul $106 nightly $123 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/62bda261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/c93aa40d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/926efd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/92000000/91660000/91653100/91653050/c7ae48fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4098/Lyle SW · Brand New Home in Beautiful Golf Course Community [](https://www.expedia.com/Las-Cruces-Hotels-4098Lyle-SW-Brand-New-Home-In-Beautiful-Golf-Course-Community.h91653050.Hotel-Information) Las Cruces 10/10 Exceptional (14 reviews) "Nice, new and clean place. Nearby amenities and places to eat. Would book again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler $300 nightly $321 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-4098Lyle-SW-Brand-New-Home-In-Beautiful-Golf-Course-Community.h91653050.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/26ee5797.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/2718f0bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/a3f63928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/e1d11c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Las Cruces [](https://www.expedia.com/Las-Cruces-Hotels-Hilton-Garden-Inn-Las-Cruces.h2870330.Hotel-Information) Las Cruces 9.2/10 Wonderful (1,006 reviews) "Is a lovely place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle $106 nightly $122 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Hilton-Garden-Inn-Las-Cruces.h2870330.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/7588e101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/80f58473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/e6e7721e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/60000000/59200000/59194900/59194832/ce945618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Family-Friendly 3BR2BA Home with Enclosed Backyard [](https://www.expedia.com/Las-Cruces-Hotels-Lotus-Blossom.h59194832.Hotel-Information) Las Cruces 8.8/10 Excellent (33 reviews) "nice neighborhood, clean house, quick response from host, will be returning for sure" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex A. $247 nightly $281 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Lotus-Blossom.h59194832.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/56b96b71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/9419cf92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/fbac0868.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/124000000/123710000/123709300/123709278/e1387651.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2 bedroom retreat at the end of the street equipped for any length stay [](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information) Las Cruces 10/10 Exceptional (4 reviews) "Very clean with a very responsive host." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wallace A. $172 nightly $196 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Charming-2-Bedroom-Retreat-At-The-End-Of-The-Street-Equipped-For-Any-Length-Stay.h123709278.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/0606d2be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/c7b17bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/fa527983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/94000000/93500000/93494600/93494538/62e23b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 4 Bedroom Contemporary Model Home [](https://www.expedia.com/Las-Cruces-Hotels-4-Bedroom-Contemporary-Model-Home.h93494538.Hotel-Information) Las Cruces 9.2/10 Wonderful (34 reviews) "Great stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caroline M. $225 nightly $244 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-4-Bedroom-Contemporary-Model-Home.h93494538.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/4511722c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/6e9242db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/6ee2a508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/80000000/79890000/79880500/79880444/9db61b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish & Comfy House with Backyard and Parking [](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information) Las Cruces 10/10 Exceptional (32 reviews) "Great location and perfect for our needs." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer M. $308 nightly $311 total Apr 26 - Apr 27 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Stylish-Comfy-House-With-Backyard-And-Parking.h79880444.Hotel-Information) ![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/50000/42400/42327/8d2f8dc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42400/42327/0ab880c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/50000/42400/42327/216b3948.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/1000000/50000/42400/42327/9ecb0370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Las Cruces/White Sands Area [](https://www.expedia.com/Las-Cruces-Hotels-Super-8-By-Wyndham-Las-CrucesWhite-Sands-Area.h42327.Hotel-Information) Las Cruces 7.2/10 Good (1,001 reviews) "I have stayed here several times and it has always been a good visit." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon $48 nightly $57 total Apr 22 - Apr 23 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Super-8-By-Wyndham-Las-CrucesWhite-Sands-Area.h42327.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/798cead2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/23aab0c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/f9d151d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/34c507ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Mission Inn [](https://www.expedia.com/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) Las Cruces 8.8/10 Excellent (1,227 reviews) "Clean room, friendly staff and good morning breakfast." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Don $86 nightly $99 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/d537f667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/d60d42c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/490d7bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/88000000/87800000/87796300/87796251/9523e9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yucca House | Views, Jetted Bath, Central Retreat [](https://www.expedia.com/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information) Las Cruces 9.8/10 Exceptional (38 reviews) "Comfortable, clean, bright accommodations. Well-stocked kitchen. Lovely backyard with beautiful view of Organ Mountains. Perfect for our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen L. $278 nightly $316 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Yucca-House-Views.h87796251.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/0ee34930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/d73b3e11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/352afc71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92190000/92186700/92186674/84d1ed9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Big Chile Inn & Suites [](https://www.expedia.com/Las-Cruces-Hotels-Big-Chile-Inn-Suites.h92186674.Hotel-Information) Las Cruces 7.0/10 Good (61 reviews) "Property is older but clean. Room was spacious and bed was very comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Faith $67 nightly $79 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Las-Cruces-Hotels-Big-Chile-Inn-Suites.h92186674.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-20&endDate=2026-04-21®ionId=132684&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Bed-And-Breakfast.d132684-aaBedAndBreakfast.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesilla-Bed-And-Breakfast.d132684-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Mesilla Hotel Reviews ![Comfort Suites University Las Cruces](https://images.trvl-media.com/lodging/1000000/50000/43200/43179/3f986bbe_y.jpg) ### Comfort Suites University Las Cruces 4/10 Poor "Parking was good, breakfast was so so Front desk personnel were non helpful and ignorant on problems we encountered. Manager was supposed to contact us on the non availability of HOT water, has not . For the price you guys charge I should have found a better place to stay. " [](https://expedia.com/Las-Cruces-Hotels-Comfort-Suites-University-Las-Cruces.h43179.Hotel-Information) ![Drury Inn & Suites Las Cruces](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723204/46263956_y.jpg) ### Drury Inn & Suites Las Cruces 10/10 Excellent "Gym and Laundry were not used" [](https://expedia.com/Las-Cruces-Hotels-Drury-Inn-Suites-Las-Cruces.h1723204.Hotel-Information) ![Hotel Encanto de Las Cruces](https://images.trvl-media.com/lodging/1000000/30000/21300/21267/5b5c1a96_y.jpg) ### Hotel Encanto de Las Cruces 8/10 Good "Clean, quiet and high class. The only downside was they didnt clean our room the last night" [](https://expedia.com/Las-Cruces-Hotels-Hotel-Encanto-De-Las-Cruces.h21267.Hotel-Information) ![Days Inn by Wyndham Las Cruces](https://images.trvl-media.com/lodging/1000000/20000/15100/15035/b4a415ed_y.jpg) ### Days Inn by Wyndham Las Cruces 10/10 Excellent "🙂" [](https://expedia.com/Las-Cruces-Hotels-Days-Inn-By-Wyndham-Las-Cruces.h15035.Hotel-Information) ![Hampton Inn & Suites Las Cruces I-10](https://images.trvl-media.com/lodging/13000000/12820000/12817800/12817768/dec3042f_y.jpg) ### Hampton Inn & Suites Las Cruces I-10 10/10 Excellent "Comfortable and convenient " [](https://expedia.com/Las-Cruces-Hotels-Hampton-Inn-Suites-Las-Cruces-I-10.h12817768.Hotel-Information) ![Comfort Inn & Suites Las Cruces Mesilla](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353805/518ac77c_y.jpg) ### Comfort Inn & Suites Las Cruces Mesilla 6/10 Okay "Was not worth the price we paid for. Need to drop the price" [](https://expedia.com/Las-Cruces-Hotels-Comfort-Inn-Suites-Las-Cruces-Mesilla.h1353805.Hotel-Information) ![Hilton Garden Inn Las Cruces](https://images.trvl-media.com/lodging/3000000/2880000/2870400/2870330/26ee5797_y.jpg) ### Hilton Garden Inn Las Cruces 10/10 Excellent "Nice breakfast " [](https://expedia.com/Las-Cruces-Hotels-Hilton-Garden-Inn-Las-Cruces.h2870330.Hotel-Information) ![Best Western Mission Inn](https://images.trvl-media.com/lodging/1000000/30000/20600/20506/798cead2_y.jpg) ### Best Western Mission Inn 8/10 Good "The staff goes above and beyond. The rooms were older but much larger than the cramped newer hotels. The ground’s actually had green areas with trees and outdoor seating. The breakfast was better than the traditional continental type breakfast offered at new box hotels. We enjoyed it so much we stayed both going and returning on our trip. It was very relaxing. " [](https://expedia.com/Las-Cruces-Hotels-Best-Western-Mission-Inn.h20506.Hotel-Information) ![La Quinta Inn by Wyndham Las Cruces Mesilla Valley](https://images.trvl-media.com/lodging/1000000/20000/15400/15369/c71afdd0_y.jpg) ### La Quinta Inn by Wyndham Las Cruces Mesilla Valley 2/10 Terrible "Close this property down, now." [](https://expedia.com/Las-Cruces-Hotels-La-Quinta-Inn-By-Wyndham-Las-Cruces-Mesilla-Valley.h15369.Hotel-Information) ## Find out more about Mesilla ## Mesilla B&B information | Number of reviews | 8,643 | | ----------------- | ----- | | Accommodation | 0 B&B | | Lowest Price | $57 | | Highest Price | $321 | ## Frequently asked questions ### What is the nightly rate for a Bed and Breakfast in Mesilla? ### When is the best time to book a Bed & Breakfast in Mesilla? > During this period, daytime temperatures typically range from the mid-60s to low 80s Fahrenheit, making it comfortable for outdoor activities such as strolling through the historic plaza or enjoying a leisurely bike ride along the scenic paths. The pleasant weather also encourages visitors to explore local attractions, including the nearby Organ Mountains and the stunning desert landscapes that surround Mesilla. > > > For those seeking a more budget-friendly option, consider visiting in November. While this month is less busy, you can still enjoy the unique charm of Mesilla, with opportunities for quieter exploration and the chance to experience local events without the crowds. ### What is the difference between a Mesilla Bed & Breakfast and a hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Mesillia Plaza ](https://www.expedia.com/Mesillia-Plaza-Hotels.0-l656813499404554240-0.Travel-Guide-Filter-Hotels) - [Hotels near Fountain Theatre ](https://www.expedia.com/Fountain-Theatre-Hotels.0-l553248621532643092-0.Travel-Guide-Filter-Hotels) - [Hotels near Fountain Theater ](https://www.expedia.com/Fountain-Theater-Hotels.0-l553248621532643091-0.Travel-Guide-Filter-Hotels) - [Hotels near Rio Grande Vineyards and Winery ](https://www.expedia.com/Rio-Grande-Vineyards-And-Winery-Hotels.0-l553248621532643097-0.Travel-Guide-Filter-Hotels) - [Las Cruces Hotels ](https://www.expedia.com/Las-Cruces-Hotels.d2137.Travel-Guide-Hotels) - 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