Find 5 Star Hotels in Downtown San Francisco, CA from $110

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Check availability on Downtown San Francisco 5 Star Hotels

Our top choices for Downtown San Francisco 5-star hotels

Terrace/patio
Fairmont San Francisco

Fairmont San Francisco

Fairmont San Francisco
5.0 star property
Downtown San Francisco
9.0 out of 10, Wonderful, (1429)
"Beautiful hotel "
United States
Xandy
$260 nightly
The price is $306
Dec 14 - Dec 15
Total with taxes and fees
Fairmont San Francisco
View from property
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (1000)
"Everything was fantastic including the breakfast!"
United States
David
$269 nightly
The price is $317
Jan 2 - Jan 3, 2026
Total with taxes and fees
Palace Hotel, a Luxury Collection Hotel, San Francisco
City view
Taj Campton Place

Taj Campton Place

Taj Campton Place
5.0 star property
Union Square
9.2 out of 10, Wonderful, (1001)
"Wonderful Staff and hospitality."
United States
Rachel
$193 nightly
The price is $227
Dec 18 - Dec 19
Total with taxes and fees
Taj Campton Place
Terrace/patio
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1002)
"great room and staff. "
United States
chunguang
$316 nightly
The price is $372
Jan 4 - Jan 5, 2026
Total with taxes and fees
Four Seasons Hotel San Francisco
2 restaurants, breakfast, lunch, dinner served; Californian cuisine
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (1000)
"Excellent "
United States
Maximus
$371 nightly
The price is $436
Dec 29 - Dec 30
Total with taxes and fees
The Ritz-Carlton, San Francisco
Breakfast, lunch, dinner served; alfresco dining
1 Hotel San Francisco

1 Hotel San Francisco

1 Hotel San Francisco
5.0 star property
Downtown San Francisco
9.2 out of 10, Wonderful, (483)
"The staff was incredible and we loved all of the design touches in the room. The attention to detail was impressive. "
United States
Eric
$407 nightly
The price is $479
Dec 22 - Dec 23
Total with taxes and fees
1 Hotel San Francisco
Rooftop terrace
Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero

Four Seasons Hotel San Francisco at Embarcadero
5.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (1003)
"The views are jaw dropping. The service is excellent in all areas, particularly broom service. Very easy to park and car service to local locations. "
United States
stephanie
$420 nightly
The price is $494
Dec 25 - Dec 26
Total with taxes and fees
Four Seasons Hotel San Francisco at Embarcadero
Suite, 1 Bedroom, Corner | Frette Italian sheets, premium bedding, down comforters, pillowtop beds
The St. Regis San Francisco

The St. Regis San Francisco

The St. Regis San Francisco
5.0 star property
Downtown San Francisco
9.4 out of 10, Exceptional, (692)
"Had a great stay "
United Kingdom
Thomas
$399 nightly
The price is $470
Dec 13 - Dec 14
Total with taxes and fees
The St. Regis San Francisco
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Downtown San Francisco.
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center San Francisco CA
$183 nightly
The price is $215 total per night from Dec 14 to Dec 15
$215 total
Dec 14 - Dec 15
Total with taxes and fees
9.2/10 Wonderful! (1,987 reviews)
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PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Downtown San Francisco

For all the features of a sophisticated downtown urban stay, this neighborhood in the bustling heart of the city can’t be beat.

See all hotels in Downtown San Francisco
Downtown San Francisco featuring railway items

Top Downtown San Francisco Hotel Reviews

Fairmont San Francisco

Fairmont San Francisco

10/10 Excellent
"⭐️⭐️⭐️⭐️⭐️ 5/5 — A Truly Magical Stay! I can’t say enough wonderful things about this beautiful hotel. From the moment we arrived, the service was exceptional—warm, attentive, and genuinely welcoming. Every staff member went above and beyond to make our stay feel special. But what absolutely stole my heart was the Christmas décor. It was truly magical—like stepping straight into a holiday movie. Sparkling lights, stunning trees, festive details in every corner… it felt whimsical and full of joy. The atmosphere alone made our stay unforgettable. If you’re looking for a place that delivers both luxury and heartwarming holiday charm, this hotel is a dream. I will absolutely be returning and recommending it to everyone one i know thank you for a wonderful stay. everyone I know"
Florencia 3-night trip
Posted 6 days ago
Fairmont San Francisco

Find out more about Downtown San Francisco

You enjoy the finer things in life, both at home and on vacation. Why not demand total luxury during your jaunt to Downtown San Francisco? There's no reason to delay a getaway to Downtown San Francisco any longer. In fact, the sheer number of visitors to Downtown San Francisco has swelled during the last year. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Downtown San Francisco and get ready to be pampered like never before.

5-Star Hotels in Downtown San Francisco

You'll have a fantastic time at one of these 5-star hotels. Michelin-starred restaurants, concierges, and pillow-fluffing are all at the ready. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you pick out your next adventure? A deep-tissue massage to help your cares fall away? Beautiful furniture, delectable chocolate desserts, and even a hot tub in the bathroom...these hotels are one-of-a-kind.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Downtown San Francisco are waiting for you to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Downtown San Francisco 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. This is a great time to find 5-star hotel deals in @region! Don't put off your dream vacation any longer. Select one of the 5-star hotels in Downtown San Francisco today and soothe yourself in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Downtown San Francisco?
Get the indulgent experience at Four Seasons Hotel San Francisco, Taj Campton Place and The St. Regis San Francisco. These are some of the 5-star stays around the San Francisco neighborhood of Downtown San Francisco that are rated highest by our guests.
How much does it cost to stay in a 5-star hotel in Downtown San Francisco?
How much you pay for a 5-star hotel in Downtown San Francisco depends on things such as when you plan to travel and the length of your break. Our insider tip for landing the best deal? Use our pricing filters to check out all of the available options for your preferred dates.

  • Search for the lowest price per night from $110

What makes a hotel 5 stars in Downtown San Francisco?
In Downtown San Francisco, a hotel must provide a specific amount of upscale amenities to earn 5 stars. These may include on-site gyms, saunas and spas, gourmet restaurants, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their extraordinary standard of service. You'll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer extra touches like welcome gifts.

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