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Featured San Francisco Luxury Hotels

See all 509 Hotels in San Francisco
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,051 reviews)
Although we had to pay top dollar due to high occupancy, our room was wonderful !
  Sep 13, 2017

$280

$280
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,535 reviews)
Wouldn't hesitate to recommend this wonderful hotel. Staff are excellent and willing to go the extra mile for guests, room was spotlessly clean and the location was convenient for shopping as well as accessing public transport services. The hotel food is very expensive but there are plenty of other ...
  Sep 20, 2017

$235

$235
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (583 reviews)
Oh, that hill back to the hotel!!We loved the Scarlett Huntington. We upgraded to a deluxe room and it was worth it. Lots of space and a huuuge bed. The hotel is in nob hill which is far enough out of union Square to keep away from the noise but it's still close enough to walk in. Just beware the massive hill when coming back ...
  Sep 19, 2017

$325

$325
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.6 out of 5 (206 reviews)
Nice hotel beautiful view Wow beautiful view on the bridge to bridge room Concierge was Really helpful But no pool and not a great lobby
  Sep 13, 2017

$349

$349
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (404 reviews)
AMAZING HOTEL Amazing hotel, great stuff, delicious food and drinks ! Overall great experiences !!!!
  Sep 7, 2017

$332

$332
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
4.5 out of 5.0
4.4 out of 5 (903 reviews)
Very clean and nice. The bar is also great Good hotel with friendly staff. Close to everything.
  Sep 19, 2017

$197

$197
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,611 reviews)
Hotel Serrano was close to Union Square, big bus pickup and bike rentals. Around 10 minute walk to Chinatown. 15 minute walk to SFMOMA. Room was a little small but I expected that in an older building. However, room was clean and the staff was friendly and helpful.
  Sep 20, 2017

$208

$208
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,752 reviews)
Great but expensive Very clean and very comfortable! Only complaint is regarding the terrible out-of-control homeless situation on nearby streets (hundreds of unfortunate souls). Did not feel safe walking far from hotel. SF is going down the tubes!
  Sep 19, 2017

$194

$194
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Recently booked Luxury Hotels in San Francisco

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The Westin San Francisco Airport
4.0 out of 5.0
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When you'll take your luxury hotel with a side of thrilling city attractions, you've found your niche in San Francisco. As one of the most intriguing destinations for travelers who want to check out city life, San Francisco is a great place to make memories. Brilliant experiences, delicious eats, and chances to take terrific photos: these are just a few of the reasons to take a trip to San Francisco. You'll enjoy the most popular performances, treat yourself to the city's best food, and marvel at the most popular attractions in the region. Naturally, you'll book a room at a luxury hotel! Extravagant experiences are right up your alley, so book your luxury hotel in San Francisco on Expedia.com today, and your relaxing escape is off to a good start.

5-Star Vacations in San Francisco

If you doubt that San Francisco is full of marvelous things to do, consider that 864,816 people are happy to call it home. No matter what brings you to San Francisco, the destination always delivers. San Francisco is full of dreamy hotels on top of appealing attractions, so it's no surprise that travelers come back. Book early to get the best room!

A luxury retreat is the perfect opportunity to indulge in art, culture, and spa treatments. When you book your travel on Expedia.com, you can enjoy it all. Thanks to our spectacular room rates, you'll still have enough money for the most fun and free-spirited things to do. After an eventful day of exploration, your luxury suite awaits. Before you crawl into bed, order a glass of wine to your room and revel in your successful day. The luxury rooms and suites in San Francisco will put you into a state of serenity before you know it.

Luxury Hotels in San Francisco

It's that time; you're ready to get swept away in The Baghdad by the Bay, and Expedia.com is here to save the day. Browse the wealth of reviews on dozens of hotels and then book your ideal room in minutes. Luxury accommodations offer amenities like elegant suites and concierge services. Some of the city's luxe accommodations even feature upscale penthouses, while others offer rejuvenating spa treatments. Use our mobile booking app to find and book an incredible 5-star hotel in San Francisco, and before you know it you'll be getting pampered in paradise!