Title: Murphysboro Vacation Rentals from $151: Search Short-Term Rentals | Expedia.com

[Murphysboro Travel Guide](https://expedia.com/Murphysboro.dx55857)[Hotels in Murphysboro](https://expedia.com/Murphysboro-Hotels.d55857.Travel-Guide-Hotels)[Flights to Murphysboro](https://expedia.com/Cheap-Flights-To-Murphysboro.d55857.Travel-Guide-Flights)[Car Rentals in Murphysboro](https://expedia.com/Car-Rentals-In-Murphysboro.d55857.Car-Rental-Guide)[Murphysboro Vacation Packages](https://expedia.com/Murphysboro.d55857.Destination-Travel-Guides)

![Lake Murphysboro State Park which includes autumn leaves, picnicing and forests](https://images.trvl-media.com/place/6186677/108d6e6a-45bc-4623-a9ba-f3146d9aa969.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Southernmost Illinois Tourism Bureau

![](https://images.trvl-media.com/place/6186677/108d6e6a-45bc-4623-a9ba-f3146d9aa969.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=55857&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=55857&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=55857&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=55857&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Murphysboro vacation rentals

![House (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/aa6e717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ed90f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ac16db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/02464d31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakefront, Pet-friendly 1BR w/ Porch & Fire Pit

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

Murphysboro

$217 nightly

$238 total

Feb 8 - Feb 9

Total with taxes and fees

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-20&endDate=2026-02-21&regionId=55857&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Murphysboro%2C+Illinois%2C+United+States+of+America&regionId=55857&latLong=37.768705%2C-89.328771&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CONDO)

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## Top Murphysboro Hotel Reviews

![Baymont by Wyndham Marion](https://images.trvl-media.com/lodging/1000000/20000/19300/19275/7eb84743_y.jpg)

### Baymont by Wyndham Marion

10/10 Excellent

"121909"

[](https://expedia.com/Carbondale-Hotels-Baymont-By-Wyndham-Marion.h19275.Hotel-Information)

![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg)

### Drury Inn & Suites Marion

10/10 Excellent

"Our room was clean and tidy. "

[](https://expedia.com/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information)

![Country Inn & Suites by Radisson, Marion, IL](https://images.trvl-media.com/lodging/3000000/2460000/2457400/2457332/6bf09f9e_y.jpg)

### Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent

"Room was clean and in good repair with plenty of accessible outlets. The staff was friendly and helpful. The shower had great pressure and volume."

[](https://expedia.com/Carbondale-Hotels-Country-Inn-Suites-By-Radisson.h2457332.Hotel-Information)

![Walker's Bluff Casino Resort](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/1aec7f72_y.jpg)

### Walker's Bluff Casino Resort

10/10 Excellent

"The room was clean. Staff was amazing. Bed was comfy. "

[](https://expedia.com/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information)

![Best Western Marion Hotel](https://images.trvl-media.com/lodging/1000000/100000/98000/97975/86964c5d_y.jpg)

### Best Western Marion Hotel

10/10 Excellent

"clean room, great service, and breakfast was good (biscuits and gravy, sausage, and eggs). Night-time staff was excellent, very nice, accommodating, and made the check in process painless. Would recommend to anyone travelling to stay here. "

[](https://expedia.com/Carbondale-Hotels-Best-Western-Marion-Hotel.h97975.Hotel-Information)

![Quality Inn And Suites](https://images.trvl-media.com/lodging/1000000/30000/27100/27086/5ddb47c0_y.jpg)

### Quality Inn And Suites

10/10 Excellent

"Everyone was nice"

[](https://expedia.com/Carbondale-Hotels-Quality-Inn-And-Suites.h27086.Hotel-Information)

![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](https://images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/2785ae14_y.jpg)

### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

10/10 Excellent

"Yes, very clean and service was great."

[](https://expedia.com/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information)

![Best Western Saluki Inn](https://images.trvl-media.com/lodging/1000000/120000/119200/119178/3da90d9b_y.jpg)

### Best Western Saluki Inn

10/10 Excellent

"Great staff and very clean!!"

[](https://expedia.com/Carbondale-Hotels-Best-Western-Saluki-Inn.h119178.Hotel-Information)

![Super 8 by Wyndham Carbondale](https://images.trvl-media.com/lodging/1000000/440000/439700/439693/8adbc8b5_y.jpg)

### Super 8 by Wyndham Carbondale

10/10 Excellent

"Clean room, friendly staff"

[](https://expedia.com/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information)

## Find out more about Murphysboro

**Everything you need to know about Murphysboro vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Murphysboro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Murphysboro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Murphysboro vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Murphysboro. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Murphysboro in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $151 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Murphysboro rentals**

At Expedia, we put the best Murphysboro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Murphysboro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Murphysboro vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Murphysboro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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- [Vacation Homes in Murphysboro ](https://expedia.com/Murphysboro-Private-Vacation-Homes.d55857-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cabin Rentals in Murphysboro ](https://expedia.com/Murphysboro-Cabins.d55857-aaCabins.Travel-Guide-Accommodation)
- [RV Parks in Murphysboro ](https://expedia.com/Murphysboro-RV-Parks.d55857-aaRVParks.Travel-Guide-Accommodation)
- [Apartments in Murphysboro ](https://expedia.com/Murphysboro-Apartments.d55857-aaApartments.Travel-Guide-Accommodation)
- [Motels in Murphysboro ](https://expedia.com/Murphysboro-Motels.d55857-aaMotels.Travel-Guide-Accommodation)
- [Cottages in Murphysboro ](https://expedia.com/Murphysboro-Cottages.d55857-aaCottages.Travel-Guide-Accommodation)
- [Farmstay in Murphysboro ](https://expedia.com/Murphysboro-Agritourism.d55857-aaAgritourism.Travel-Guide-Accommodation)
- [B&B in Murphysboro ](https://expedia.com/Murphysboro-Bed-And-Breakfast.d55857-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Lodges in Murphysboro ](https://expedia.com/Murphysboro-Lodges.d55857-aaLodges.Travel-Guide-Accommodation)
- [Guest Houses in Murphysboro ](https://expedia.com/Murphysboro-Guest-Houses.d55857-aaGuestHouses.Travel-Guide-Accommodation)
- [Condo Rentals in Murphysboro ](https://expedia.com/Murphysboro-Condos.d55857-aaCondos.Travel-Guide-Accommodation)
- [Resorts in Murphysboro ](https://expedia.com/Murphysboro-Resorts.d55857-aaResorts.Travel-Guide-Accommodation)

## Frequently asked questions

### Are there vacation rentals in Murphysboro?

### What are some of the best vacation rentals in Murphysboro?

### How many vacation rentals are there in Murphysboro?

### What’s there to see and do in Murphysboro?

### What’s a vacation rental in Murphysboro like?

### Expedia's Latest Trends

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