A river with a dam, surrounded by greenery and a clear sky.

Palmyra Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Palmyra vacation rentals

1. Sunlit Studio on Historic Main Street

Sunlit Studio on Historic Main Street
Palmyra
10.0 out of 10, Exceptional, (2 reviews)
"Lovely stay at a very cute property! We stayed overnight for a friend’s wedding which was at the Iron Gate Estate (less than 2 miles away). Perfect stay for a couple! 10/10 - highly recommend!"
United States
Brent T.
$144 nightly
The price is $154
Sep 8 - Sep 9
Total with taxes and fees
Sunlit Studio on Historic Main Street
A bedroom with a bed, nightstands, a TV, a chair, and a door.

2. Charming 3-bedroom house, 2-car garage, and pickleball court

Charming 3-bedroom house, 2-car garage, and pickleball court
Hannibal
10.0 out of 10, Exceptional, (2 reviews)
"The space was great for my family. It was clean, comfortable and Shelby was a great host. We will surely be back!"
United States
Jeanne M.
$207 nightly
The price is $235
Sep 8 - Sep 9
Total with taxes and fees
Charming 3-bedroom house, 2-car garage, and pickleball court
A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

3. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (15 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
$247 nightly
The price is $279
Sep 6 - Sep 7
Total with taxes and fees
Vibey home a few blocks from downtown Hannibal
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

4. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21 reviews)
"House was perfect for our stay."
United States
Brent W.
$256 nightly
The price is $288
Sep 7 - Sep 8
Total with taxes and fees
Modern and comfy home five minutes from downtown
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

5. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (222 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
$233 nightly
The price is $247
Sep 7 - Sep 8
Total with taxes and fees
Peaceful, Country Cottage with Open Floor Plan
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

6. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (43 reviews)
"Wonderful place to stay!"
United States
Kari
$197 nightly
The price is $228
Sep 14 - Sep 15
Total with taxes and fees
Lighthouse Inn & Suites
A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

7. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
$138 nightly
The price is $157
Sep 8 - Sep 9
Total with taxes and fees
Aunt Lele's Cozy Cottage
A building with a glass door marked "108" and a sign for "Web Print Radio Television Public Relations."

8. The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
Hannibal
9.8 out of 10, Exceptional, (14 reviews)
"Great experience! Lots of space and the hostess thought of everything. We will stay here again when we visit Hannibal. "
United States
Dianna M.
$140 nightly
The price is $151
Sep 7 - Sep 8
Total with taxes and fees
The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

9. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.6 out of 10, Exceptional, (64 reviews)
"This place was amazing!"
United States
Nancy S.
$176 nightly
The price is $191
Sep 8 - Sep 9
Total with taxes and fees
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A spacious loft with exposed wooden beams, a large clock on the wall, a rustic brick wall, and a cozy seating area with a sofa and a coffee table.

10. Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Hannibal
10.0 out of 10, Exceptional, (7 reviews)
"Pretty place. Awesome location. Had such a good time"
United States
janette b.
$235 nightly
The price is $267
Sep 7 - Sep 8
Total with taxes and fees
Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
A bedroom with a bed, a desk, a chair, a TV, and a window.

11. Updated efficiency unit attached to the Parlor on Paris - Rent both and save

Updated efficiency unit attached to the Parlor on Paris - Rent both and save
Hannibal
9.6 out of 10, Exceptional, (5 reviews)
"Great for a weekend get away."
United States
Jordon S.
$225 nightly
The price is $254
Sep 30 - Oct 1
Total with taxes and fees
Updated efficiency unit attached to the Parlor on Paris - Rent both and save
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

12. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.8 out of 10, Exceptional, (23 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
$232 nightly
The price is $252
Sep 7 - Sep 8
Total with taxes and fees
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A modern house with a stone facade, a dark garage door, and a well-lit entrance.

13. Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.

Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
Quincy
10.0 out of 10, Exceptional, (6 reviews)
"Very nice and clean place"
United States
G K.
$245 nightly
The price is $280
Sep 16 - Sep 17
Total with taxes and fees
Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
A park with a pond, picnic tables, and a gazebo.

14. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.2 out of 10, Wonderful, (21 reviews)
"Cozy and well equipped with everything we may have needed"
United States
Olivia
$102 nightly
The price is $108
Sep 14 - Sep 15
Total with taxes and fees
Cannon Dam Cabins
A cozy living room with a sofa, armchair, and a coffee table. There is a wooden bookshelf and a TV mounted on the wall.

15. Great place for allot of fun events & all your people under 1 roof low cost!

Great place for allot of fun events & all your people under 1 roof low cost!
Hunnewell
7.8 out of 10, Good, (7 reviews)
"It was great we stayed there while deer hunting. It was perfect. Owners were Very friendly and accommodating. Definitely be back on our next hunting trip. "
United States
Mike S.
$176 nightly
The price is $189
Sep 6 - Sep 7
Total with taxes and fees
Great place for allot of fun events & all your people under 1 roof low cost!
A park with a playground, a pond, and residential buildings in the background.

16. Deluxe two queen bed motel room packed with amenities.

Deluxe two queen bed motel room packed with amenities.
Perry
10.0 out of 10, Exceptional, (1 review)
"Older, but very clean and nice. "
United States
Anonymous traveler
$115 nightly
The price is $121
Sep 8 - Sep 9
Total with taxes and fees
Deluxe two queen bed motel room packed with amenities.
An outdoor patio with wicker furniture, a fire pit, and a TV on a cabinet.

17. MTL HUNTING LAYAWAY & OUTDOOR HANGOUT

MTL HUNTING LAYAWAY & OUTDOOR HANGOUT
Center
8.8 out of 10, Excellent, (3 reviews)
"Perfect for what we needed for a night. The host replied very efficiently to any questions we had. All that we needed was there. Thank you!!!"
United States
Crystal O.
$195 nightly
The price is $206
Sep 23 - Sep 24
Total with taxes and fees
MTL HUNTING LAYAWAY & OUTDOOR HANGOUT
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island with bar stools.

18. Shouse Near Mark Twain Lake!

Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (12 reviews)
"This was our second stay, and it was just as great as the first time! Plenty of room to play, huge TVs for family movie night, and a well equipped kitchen for serving meals. Thank you! "
United States
Christina H.
$285 nightly
The price is $301
Sep 7 - Sep 8
Total with taxes and fees
Shouse Near Mark Twain Lake!
A modern kitchen with white cabinets, a refrigerator, microwave, and a coffee maker.

19. Charming 1-bedroom cottage in Lewistown!

Charming 1-bedroom cottage in Lewistown!
lewistown
10.0 out of 10, Exceptional, (3 reviews)
"This property exceeded all our expectations. It was incredibly clean, beautifully modern, inviting, and very comfortable. The setting was so peaceful and quiet, making it the perfect place to unwind. The hosts thought of everything to ensure a relaxing stay."
United States
TRACEY H.
$188 nightly
The price is $202
Sep 6 - Sep 7
Total with taxes and fees
Charming 1-bedroom cottage in Lewistown!
A residential building with a wooden deck, outdoor seating, and a trash can.

20. Historical German Apartment

Historical German Apartment
Bethel
$130 nightly
The price is $139
Sep 7 - Sep 8
Total with taxes and fees
Historical German Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Palmyra Hotel Reviews

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

10/10 Excellent
"Clean older property nice breakfast."
Tom 1-night trip
Posted 5 hours ago
Quality Inn & Suites Hannibal West

Find out more about Palmyra

Everything you need to know about Palmyra vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Palmyra vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Palmyra vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Palmyra vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Palmyra. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Palmyra in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $108 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Palmyra rentals

At Expedia, we put the best Palmyra vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Palmyra rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Palmyra vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Palmyra. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Palmyra?

Yes, we offer vacation rentals close to top points of interest in Palmyra, or you can select a secluded option if you're looking for a relaxing stay. Palmyra is known for its coffeehouses and restaurants. Make sure you have time to check out the museums while you're in the area.

What are some of the best vacation home rentals that Palmyra has to offer?

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi: This vacation home rental outside of Palmyra offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a selection of games.

What can I see and do in Palmyra?

Mississippi River and Flower City Park are a couple of scenic spots to enjoy the outdoors, whereas Gardner House Museum is one of the cultural attractions. While here, Dr. J.W. Well Nature Park and Bay Island are other places worth a visit.

What’s a vacation rental in Palmyra like?

Vacation rentals are privately owned properties you can book for several days or longer in Palmyra. Vacation rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for a family trip.