A river with a dam, surrounded by greenery and a clear sky.

Palmyra Vacation Rentals

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Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Palmyra vacation rentals

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

1. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (47 reviews)
"Wonderful place to stay!"
United States
Kari
$192 nightly
The price is $221
Oct 4 - Oct 5
Total with taxes and fees
Lighthouse Inn & Suites
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

2. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.8 out of 10, Exceptional, (24 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
$237 nightly
The price is $257
Oct 5 - Oct 6
Total with taxes and fees
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

3. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (67 reviews)
"Great location for downtown exploring."
United States
Lisa B.
$172 nightly
The price is $186
Nov 2 - Nov 3
Total with taxes and fees
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A bedroom with a bed, nightstands, a TV, a chair, and a door.

4. Charming 3-bedroom basement apartment, 2-car garage, and pickleball court

Charming 3-bedroom basement apartment, 2-car garage, and pickleball court
Hannibal
10.0 out of 10, Exceptional, (3 reviews)
"We absolutely loved our stay! The house was fantastic—spotlessly clean, comfortable, and in a perfect location. Everything was easy to use and worked exactly as it should, and every one of our needs was met. The attached two-car garage was a huge bonus, especially on a rainy day when we could go straight into the house without getting wet! The home was also extremely kid-friendly, which made our stay even more enjoyable. Shelby was an amazing host, and we couldn’t have asked for a better...
United States
William C.
$219 nightly
The price is $248
Oct 8 - Oct 9
Total with taxes and fees
Charming 3-bedroom basement apartment, 2-car garage, and pickleball court
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

5. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (224 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
$233 nightly
The price is $247
Oct 4 - Oct 5
Total with taxes and fees
Peaceful, Country Cottage with Open Floor Plan
A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

6. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (15 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
$256 nightly
The price is $289
Oct 6 - Oct 7
Total with taxes and fees
Vibey home a few blocks from downtown Hannibal
A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

7. Deck + River View: Loft in Downtown Hannibal

Deck + River View: Loft in Downtown Hannibal
3.0 star property
Hannibal
$230 nightly
The price is $265
Oct 4 - Oct 5
Total with taxes and fees
Deck + River View: Loft in Downtown Hannibal
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

8. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21 reviews)
"House was perfect for our stay."
United States
Brent W.
$264 nightly
The price is $298
Oct 7 - Oct 8
Total with taxes and fees
Modern and comfy home five minutes from downtown
A building with a glass door marked "108" and a sign for "Web Print Radio Television Public Relations."

9. The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
Hannibal
9.8 out of 10, Exceptional, (17 reviews)
"We had a great stay here. It was much larger than expected with a sitting room, bedroom, bath, kitchen and laundry area. In the heart of all in town and yet very safe."
United States
Dan R.
$125 nightly
The price is $135
Oct 26 - Oct 27
Total with taxes and fees
The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
A compact kitchen with a refrigerator, stove, microwave, and a dining area with chairs.

10. Cannon Dam Cabins

Cannon Dam Cabins
3.0 star property
Perry
9.4 out of 10, Exceptional, (24 reviews)
"Amazing place to stay! You can’t beat the indoor pool whether it is storming or feels like the fires from hell are raining on earth you can still enjoy a great swim without worrying about lightning or burning to death. The people are incredibly kind and on top of anything you may need and the cabins are a perfect relaxing get away with nice a/c and plenty of sleeping space! Thank you for another amazing stay!"
United States
Erika
$103 nightly
The price is $109
Oct 4 - Oct 5
Total with taxes and fees
Cannon Dam Cabins
A bedroom with a bed, a desk, a chair, a TV, and a window.

11. Updated efficiency unit attached to the Parlor on Paris - Rent both and save

Updated efficiency unit attached to the Parlor on Paris - Rent both and save
Hannibal
9.6 out of 10, Exceptional, (5 reviews)
"Great for a weekend get away."
United States
Jordon S.
$179 nightly
The price is $201
Oct 4 - Oct 5
Total with taxes and fees
Updated efficiency unit attached to the Parlor on Paris - Rent both and save
A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

12. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
$138 nightly
The price is $157
Oct 11 - Oct 12
Total with taxes and fees
Aunt Lele's Cozy Cottage
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

13. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (52 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
$191 nightly
The price is $218
Oct 19 - Oct 20
Total with taxes and fees
Spacious & Modern 2BR Home with Attached Garage
A modern house with a stone facade, a dark garage door, and a well-lit entrance.

14. Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.

Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
Quincy
10.0 out of 10, Exceptional, (8 reviews)
"Very nice and clean place"
United States
G K.
$229 nightly
The price is $261
Oct 8 - Oct 9
Total with taxes and fees
Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
A modern kitchen with wooden cabinets, stainless steel appliances, and a large island with bar stools.

15. Shouse Near Mark Twain Lake!

Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (12 reviews)
"This was our second stay, and it was just as great as the first time! Plenty of room to play, huge TVs for family movie night, and a well equipped kitchen for serving meals. Thank you! "
United States
Christina H.
$310 nightly
The price is $327
Oct 4 - Oct 5
Total with taxes and fees
Shouse Near Mark Twain Lake!
A park with a playground, a pond, and residential buildings in the background.

16. Deluxe two queen bed motel room packed with amenities.

Deluxe two queen bed motel room packed with amenities.
Perry
10.0 out of 10, Exceptional, (1 review)
"Older, but very clean and nice. "
United States
Anonymous traveler
$115 nightly
The price is $121
Oct 4 - Oct 5
Total with taxes and fees
Deluxe two queen bed motel room packed with amenities.
A spacious loft with exposed wooden beams, a large clock on the wall, a rustic brick wall, and a cozy seating area with a sofa and a coffee table.

17. Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Hannibal
10.0 out of 10, Exceptional, (7 reviews)
"Quiet place to stay right in the center of Hannibal’s historic area. Close to restaurants and attractions. Even has a private balcony that is nice to sit during a nice evening."
United States
Natalie H.
$235 nightly
The price is $267
Oct 4 - Oct 5
Total with taxes and fees
Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
A cozy living room with a sofa, armchair, and a coffee table. There is a wooden bookshelf and a TV mounted on the wall.

18. Great place for allot of fun events & all your people under 1 roof low cost!

Great place for allot of fun events & all your people under 1 roof low cost!
Hunnewell
8.0 out of 10, Very good, (8 reviews)
"It was great we stayed there while deer hunting. It was perfect. Owners were Very friendly and accommodating. Definitely be back on our next hunting trip. "
United States
Mike S.
$176 nightly
The price is $189
Oct 4 - Oct 5
Total with taxes and fees
Great place for allot of fun events & all your people under 1 roof low cost!
A modern kitchen with white cabinets, a refrigerator, microwave, and a coffee maker.

19. Charming 1-bedroom cottage in Lewistown!

Charming 1-bedroom cottage in Lewistown!
lewistown
10.0 out of 10, Exceptional, (3 reviews)
"This property exceeded all our expectations. It was incredibly clean, beautifully modern, inviting, and very comfortable. The setting was so peaceful and quiet, making it the perfect place to unwind. The hosts thought of everything to ensure a relaxing stay."
United States
TRACEY H.
$189 nightly
The price is $203
Oct 4 - Oct 5
Total with taxes and fees
Charming 1-bedroom cottage in Lewistown!
A compact kitchen with dark cabinets, a white refrigerator, a stove, and a toaster.

20. Historical German Apartment

Historical German Apartment
Bethel
$130 nightly
The price is $140
Oct 5 - Oct 6
Total with taxes and fees
Historical German Apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Palmyra Hotel Reviews

AmericInn by Wyndham Quincy

AmericInn by Wyndham Quincy

8/10 Good
"Clean room And staff was very friendly."
Russell 12-night trip
Posted 17 hours ago
AmericInn by Wyndham Quincy

Find out more about Palmyra

Everything you need to know about Palmyra vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Palmyra vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Palmyra vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Palmyra vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Palmyra. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Palmyra in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $109 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Palmyra rentals

At Expedia, we put the best Palmyra vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Palmyra rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Palmyra vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Palmyra. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Palmyra?

Yes, we offer vacation rentals close to top points of interest in Palmyra, or you can select a secluded option if you're looking for a relaxing stay. Palmyra is known for its coffeehouses and restaurants. Make sure you have time to check out the museums while you're in the area.

What are some of the best vacation home rentals that Palmyra has to offer?

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi: This vacation home rental outside of Palmyra offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a selection of games.

What can I see and do in Palmyra?

Mississippi River and Flower City Park are a couple of scenic spots to enjoy the outdoors, whereas Gardner House Museum is one of the cultural attractions. While here, Dr. J.W. Well Nature Park and Bay Island are other places worth a visit.

What’s a vacation rental in Palmyra like?

Vacation rentals are privately owned properties you can book for several days or longer in Palmyra. Vacation rentals provide amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you to travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for a family trip.