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Find hotels in Cape Girardeau, MO from $64

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Compare 149 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Interior
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
10.0 out of 10, Exceptional, (1)
"As described. Happy with the experience for the eclipse."
Solar Eclipse Festival Campground at Benton Speedway. April 6-8th 2024.
Fridge, microwave, oven, stovetop
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (114)
"The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!"
The price is $150
$245 total
includes taxes & fees
May 19 - May 20
Serenity South -- Gardens, River-Views, and Refreshing Space
Aerial view
Loft Apartment Across From Semo University Houch Field House. Walk To Events
10.0 out of 10, Exceptional, (70)
"Just like home"
The price is $150
$182 total
includes taxes & fees
May 24 - May 25
Loft Apartment Across From Semo University Houch Field House. Walk To Events
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Exterior
Charming Secluded Getaway Cabin within minutes of amenities
10.0 out of 10, Exceptional, (9)
"This place is amazing if what you want is relaxing. My wife and I stayed here for the total eclipse and did not see another person for our whole stay. This place sets the standard for secluded. The cabin had everything you could need for a great stay. Price was very reasonable. We could not be happier. "
Charming Secluded Getaway Cabin within minutes of amenities
Interior
Updated 3 bedroom unit with balcony!
10.0 out of 10, Exceptional, (1)
"Very nice place only downsize albeit cute is the claw foot tub with make shift shower, The unit worked very well for what we were looking for near SEMO campus"
Updated 3 bedroom unit with balcony!
Property grounds
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
10.0 out of 10, Exceptional, (202)
"beautiful place. great location. recommend to anyone"
Historical 'Kage House' Short Term Rental located in "Old Town Cape"
Fridge, microwave, oven, stovetop
Steps to Southeast Hospital - Fast Wifi - King Bed
10.0 out of 10, Exceptional, (2)
"The house was perfect for our group. It was in a great location and was exactly as advertised. I would definitely stay here again!"
Steps to Southeast Hospital - Fast Wifi - King Bed
Interior
Cozy cabins on beautiful Horseshoe Lake
9.8 out of 10, Exceptional, (18)
"We were looking for a place to view the 2024 solar eclipse and we found this cabin, which was in the path of totality! We were so excited to be able to view the eclipse from the property, which meant that we didn't have to deal with traffic getting home or to other lodging. Sherry was a great host. The cabin was quiet and clean. and just perfect for a two-night stay. "
The price is $115
$135 total
includes taxes & fees
May 19 - May 20
Cozy cabins on beautiful Horseshoe Lake
Exterior
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
9.8 out of 10, Exceptional, (17)
"Town was cute and ecclectic, stay at VRBO gave the same vibes. Very clean and fun. We only stayed for 1 night but would love to come back- stopped by Annie Laurie’s, Indie House, Kenny’s Flippin Burgers, Ebb and Flow brewery and Broadway Bistro/vintage store. We recommend all of them!"
The price is $91
$148 total
includes taxes & fees
May 19 - May 20
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Exterior
Quaint, Beautiful Home next to SEMO and Hospital
9.8 out of 10, Exceptional, (18)
"House was very nice and clean. Great neighborhood and super close to SEMO! Made visiting our son very nice having a place to stay other than a hotel room."
Quaint, Beautiful Home next to SEMO and Hospital
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
9.6 out of 10, Exceptional, (1000)
"Great place to stay!"
The price is $112
$127 total
includes taxes & fees
May 21 - May 22
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
2.5 star property
9.6 out of 10, Exceptional, (1000)
"Very nice hotel."
The price is $117
$133 total
includes taxes & fees
May 23 - May 24
Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
Lobby
Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
9.6 out of 10, Exceptional, (339)
"N/a"
The price is $130
$147 total
includes taxes & fees
Jun 2 - Jun 3
Courtyard by Marriott Cape Girardeau Downtown
Courtyard
Hampton Inn Cape Girardeau I 55 East
2.5 star property
9.6 out of 10, Exceptional, (619)
"Shower stall could've been cleaner, hairs around bottom of doors. Staff was excellent & so helpful! Design of room had T.V. located on side wall, would prefer direct view from bed location. "
The price is $108
$122 total
includes taxes & fees
Jun 2 - Jun 3
Hampton Inn Cape Girardeau I 55 East
Lobby
Drury Inn & Suites Cape Girardeau
3.0 star property
9.4 out of 10, Exceptional, (780)
"I liked the two rooms. Having breakfast included made traveling much more convenient."
The price is $108
$122 total
includes taxes & fees
May 21 - May 22
Drury Inn & Suites Cape Girardeau
Exterior
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
9.2 out of 10, Wonderful, (20)
"This property was perfect for our family and our 4 boys really enjoyed the mini golf, pool table, couch swing and signing the wall. We will definitely be coming back on our travels. Unique decor and beautiful space! "
The price is $275
$388 total
includes taxes & fees
May 19 - May 20
4-acre Home with Multiple Decks: Pool Table | Putt-Putt I 4 miles to Downtown
Lobby
Pear Tree Inn Cape Girardeau West
2.5 star property
9.0 out of 10, Wonderful, (1001)
"We never heard another person. Staff was wonderful."
The price is $64
$72 total
includes taxes & fees
May 21 - May 22
Pear Tree Inn Cape Girardeau West
Seasonal outdoor pool
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
9.0 out of 10, Wonderful, (1001)
"Reasonably price, clean, comfortable bed the only down fall is the rooms were tiny! "
The price is $67
$76 total
includes taxes & fees
May 22 - May 23
Pear Tree Inn Cape Girardeau Near the Medical Center
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
2.5 star property
9.0 out of 10, Wonderful, (373)
"A nice, clean , quiet property. Very good buy"
The price is $84
$91 total
includes taxes & fees
Jun 2 - Jun 3
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Fridge, microwave, oven, stovetop
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
9.0 out of 10, Wonderful, (16)
"Very nice, well kept place. Host is very accommodating"
Cozy Westend 4 queen beds, clean, quiet with a walk out basement
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Cape Girardeau Travel Info

Number of reviews
5,008
Accommodation
149 hotels
Highest price
$130
Lowest price
$64
Reasons to visit
Cape Splash Family Aquatic Center, Hunter Valley Winery and Lazy L Safari Park
Hotels with family-friendly amenities
7
Hotels with dining
6

Frequently asked questions

What's the best place to stay in Cape Girardeau?

Courtyard by Marriott Cape Girardeau Downtown is a favorite property for Expedia customers. This hotel is a short 6-minute walk from Mississippi River, and it offers a restaurant and free parking. Other favorite options based on traveler reviews include Hampton Inn Cape Girardeau I 55 East and Drury Inn & Suites Cape Girardeau. See all available top hotels, or vacation rentals in Cape Girardeau.

What are some of the best vacation home rentals in Cape Girardeau?

Serenity South -- Gardens, River-Views, and Refreshing Space: This highly rated vacation home rental in Cape Girardeau is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Other favorite homes for rent in Cape Girardeau are Little Blue Cottage on Spanish and Charming 2-Story- C.1847 - River Views - Fast Wifi. See all vacation rentals in Cape Girardeau.

If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?

Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Cape Girardeau.

Where can I learn more about changing or cancelling my trip to Cape Girardeau?

For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.

What's the best budget-friendly accommodation in Cape Girardeau?

Based on reviews, Auburn Place Hotel And Suites is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other good choices for your budget-friendly stay include Pear Tree Inn Cape Girardeau West and Pear Tree Inn Cape Girardeau Near the Medical Center. View all budget hotels in Cape Girardeau.

What's the best hotel for families in Cape Girardeau?

Pear Tree Inn Cape Girardeau West is a hotel with free parking and free continental breakfast, and it's a top choice on Expedia for families. Other good choices to stay with the kids include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau Near the Medical Center. Attractions like Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center are also fun for kids of all ages. Find more child-friendly accommodations in Cape Girardeau.

What is the top LGBTQ-friendly place to stay in Cape Girardeau?

Pear Tree Inn Cape Girardeau West is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Drury Inn & Suites Cape Girardeau and Drury Plaza Hotel Cape Girardeau Conference Center are two other good options for your trip. See all available hotels listed as LGBTQ-friendly in Cape Girardeau.

What's the best pet-friendly hotel in Cape Girardeau?

Auburn Place Hotel And Suites is a top hotel for people traveling with their pets, and offers an indoor pool and a fitness center for its human guests. Other good choices to stay with your pet include Pear Tree Inn Cape Girardeau West and Drury Inn & Suites Cape Girardeau. See more pet-friendly hotel accommodations in Cape Girardeau.

Where is the best hotel to stay with easy access to Southeast Missouri State University?

Courtyard by Marriott Cape Girardeau Downtown is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers a restaurant and free parking. It's located just a short 0.8 mi (1.3 km) from Southeast Missouri State University. Other good choices within a few miles include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.

What about the best place to stay close to Show Me Center?

One of the top choices for your stay is Courtyard by Marriott Cape Girardeau Downtown, located a short 1 mi (1.6 km) from Show Me Center, and this 3-star hotel offers a restaurant and free parking. Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West are two other good options within a few miles.

What's the best accommodation in Cape Girardeau that's close to historical sites?

Based on our travel expertise, Pear Tree Inn Cape Girardeau Near the Medical Center is a top hotel on Expedia for those interested in history, and it features free breakfast and free WiFi. See more options for historical stays in Cape Girardeau.

What are some accommodations with pools in Cape Girardeau?

Drury Inn & Suites Cape Girardeau is a top hotel with a pool, free buffet breakfast, and free WiFi. A couple of other options with an onsite pool include Pear Tree Inn Cape Girardeau Near the Medical Center and Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel. View all hotels with pools in Cape Girardeau.

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