Find all hotels by Omni in Downtown San Francisco, CA from $268

Visit Downtown San Francisco

Downtown San Francisco is a vibrant neighborhood known for its stunning architecture and top museums. Experience the best of Downtown San Francisco with a visit to San Francisco Museum of Modern Art, AT&T Park, and San Francisco City Hall. You'll find 188 hotels and other accommodations in Downtown San Francisco to choose from, making this an ideal home base for exploring the greater San Francisco area.

Places to Stay in Downtown San Francisco

Our travelers enjoy these top Downtown San Francisco accommodations:

• Loews Regency San Francisco: 5-star hotel with a restaurant, a 24-hour fitness center, and bar, steps from Embarcadero Center. Our guests enjoy the hotel's comfortable rooms and central location.
• Omni San Francisco Hotel: 4.5-star hotel with a restaurant, a fitness center, and bar, steps from TransAmerica Pyramid. Expedia travelers like this hotel's spacious rooms and central location.
• Hyatt Regency San Francisco: 4-star hotel with a restaurant, a 24-hour fitness center, and bar, steps from Ferry Building. Our guests rate this hotel highly for its comfortable rooms and central location.

Must See in This San Francisco Neighborhood

Explore Downtown San Francisco's landmarks like Powell and Market Cable Car Turnaround, TransAmerica Pyramid, and Civic Center Plaza and learn about the local history. You could also plan a visit to San Francisco Museum of Modern Art or AT&T Park while you're in the neighborhood.

Favorite places to visit in the surrounding Downtown San Francisco area include San Francisco City Hall, San Francisco Bay, and Westfield San Francisco Centre. Exploratorium and Lombard Street are also worth a visit when you're out sightseeing in San Francisco.

Getting Around Downtown San Francisco and the Greater San Francisco Area

For a quick way to explore the city, catch a ride on metro transit at Powell St. Station, Montgomery St. Station, or Embarcadero Station. If you want to head out of town, you can hop aboard a train at San Francisco 4th and King Station.