Find 4 Star Hotels in St. Charles, MN from $99
Most hotels are fully refundable. Because flexibility matters.
Save 10% or more on over 100,000 hotels worldwide as a One Key member.
Search over 2.9 million properties and 550 airlines worldwide.
Compare St. Charles 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
The Towers At Kahler Grand Hotel
Big River Escape Grandview Manse
DoubleTree by Hilton Hotel Rochester - Mayo Clinic Area
St. Charles Four Star Hotel Information
When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in St. Charles, Minnesota are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the St. Charles 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.
Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in St. Charles. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in St. Charles, Minnesota, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.
Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star St. Charles hotels offer everything your heart desires.
Frequently asked questions
Recent reviews of St. Charles hotelsExpedia verified reviews
St. Charles Hotels by Star Rating
Stay near popular St. Charles attractions
- Mayo Clinic
- Mayo Clinic Hospital - Saint Marys Campus
- Mississippi River
- Mayo Civic Center
- Apache Mall
- Forestville Mystery Cave State Park
- Winona State University
- Olmsted County Fairgrounds
- Root River
- University of Minnesota-Rochester
- Rochester Community and Technical College
- Rochester Recreation Center
- Regional Sports Center
- National Volleyball Center
- St. Mary's University of Minnesota
- Soldiers Field Veterans Memorial
- Rochester Civic Theater
- Whitewater State Park
- Zumbro Lake
- Plummer House
More Hotel Options in St. Charles
More Accommodation Types in St. Charles
- Vacation Homes in St. Charles (174)
- Apartments in St. Charles (66)
- Cabin Rentals in St. Charles (21)
- Condo Rentals in St. Charles (18)
- Cottages in St. Charles (10)
- Motels in St. Charles (4)
- Aparthotels in St. Charles (3)
- B&B in St. Charles (3)
- Guest Houses in St. Charles (1)
- Lodges in St. Charles (1)
- Villas in St. Charles (1)
Explore more hotels
- TownePlace Suites by Marriott Rochester Mayo Clinic Area
- Aspen Select
- Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
- Brentwood Inn & Suites
- Aspen Suites
- The Plaza Hotel & Suites Winona
- Holiday Inn Express Rochester South - Mayo Area, an IHG Hotel
- Country Inn & Suites Rochester South Mayo Clinic
- Hilton Rochester Mayo Clinic Area
- Residence Inn by Marriott Rochester Mayo Clinic Area South
- Home2 Suites by Hilton Rochester Mayo Clinic Area
- Hampton Inn & Suites Rochester-North
- Express Suites Riverport Inn & Suites
- Staybridge Suites Rochester - Mayo Clinic Area, an IHG Hotel
- Hilton Garden Inn Rochester Downtown, MN
- Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
- AmericInn by Wyndham Rochester
- Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
- Super 8 by Wyndham Winona MN
- Best Western Rochester Hotel Mayo Clinic Area/St. Mary's