Find all hotels by Independent in Downtown San Francisco, CA from $76

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Compare rooms and suites by Independent in Downtown San Francisco with rates, reviews, and availability. Most hotels are fully refundable.

Front of property - evening/night
The Pickwick Hotel

The Pickwick Hotel

3.5 star property
Downtown San Francisco
7.8 out of 10, Good, (1048)
"Friendly staff, clean, nice lobby, fun old hotel in a great location "
United States
Sharon
$107 nightly
The price is $126
Dec 9 - Dec 10
Total with taxes and fees
The Pickwick Hotel
Lobby sitting area
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

3.5 star property
Union Square
9.4 out of 10, Exceptional, (3049)
"Best location, friendly staff, had a wonderful time stayed! "
United States
Kalinda
$98 nightly
The price is $116
Dec 14 - Dec 15
Total with taxes and fees
Chancellor Hotel on Union Square
Exterior
LUMA Hotel San Francisco

LUMA Hotel San Francisco

4.0 star property
Downtown San Francisco
9.6 out of 10, Exceptional, (2396)
"Amazing hotel"
United States
Leslie
$176 nightly
The price is $207
Jan 4 - Jan 5, 2026
Total with taxes and fees
LUMA Hotel San Francisco
Lobby
Beacon Grand, A Union Square Hotel

Beacon Grand, A Union Square Hotel

4.0 star property
Union Square
9.2 out of 10, Wonderful, (1806)
"Amazing place"
Australia
David
$195 nightly
The price is $230
Dec 18 - Dec 19
Total with taxes and fees
Beacon Grand, A Union Square Hotel
Front of property
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2.0 star property
Downtown San Francisco
8.6 out of 10, Excellent, (1087)
"Excellent location, excellence staff"
United States
james
$68 nightly
The price is $80
Dec 15 - Dec 16
Total with taxes and fees
FOUND Hotel Carlton, Nob Hill
Reception
Embassy Hotel

Embassy Hotel

2.5 star property
Downtown San Francisco
6.8 out of 10, (464)
"Staff good, room clean, good location"
United States
Jarrod
$64 nightly
The price is $76
Dec 15 - Dec 16
Total with taxes and fees
Embassy Hotel
Exterior
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 star property
Union Square
8.8 out of 10, Excellent, (2837)
"Clean room, friendly staff and great location"
Canada
Christian Middleton
$125 nightly
The price is $148
Dec 9 - Dec 10
Total with taxes and fees
Handlery Union Square Hotel
Exterior
Hotel EPIK

Hotel EPIK

4.0 star property
Downtown San Francisco
7.0 out of 10, Good, (536)
"Clean rooms , nice staff "
United States
Heather
$69 nightly
The price is $82
Dec 7 - Dec 8
Total with taxes and fees
Hotel EPIK
Exterior
FOUND Hotel, San Francisco

FOUND Hotel, San Francisco

2.0 star property
Union Square
8.4 out of 10, Very Good, (668)
"Very welcoming, everything was super close by and the room was a perfect size for me."
United States
Anthony
$75 nightly
The price is $88
Dec 15 - Dec 16
Total with taxes and fees
FOUND Hotel, San Francisco
Parlour Suite | Egyptian cotton sheets, premium bedding, individually decorated
Fitzgerald Hotel

Fitzgerald Hotel

3.0 star property
Union Square
7.8 out of 10, Good, (499)
"Room was clean and the staff was friendly."
United States
Charanjit
$64 nightly
The price is $76
Dec 9 - Dec 10
Total with taxes and fees
Fitzgerald Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown San Francisco Hotel Reviews

LUMA Hotel San Francisco

LUMA Hotel San Francisco

10/10 Excellent
"Staff was very welcoming and helpful. Directed us toward late night snacks. "
Tyler 1-night trip
Posted 1 day ago
LUMA Hotel San Francisco

Find out more about Downtown San Francisco

Visit Downtown San Francisco


Downtown San Francisco is a vibrant neighborhood known for its stunning architecture and top museums. Experience the best of Downtown San Francisco with a visit to San Francisco Museum of Modern Art, AT&T Park, and San Francisco City Hall. You'll find 188 hotels and other accommodations in Downtown San Francisco to choose from, making this an ideal home base for exploring the greater San Francisco area.


Places to Stay in Downtown San Francisco


Our travelers enjoy these top Downtown San Francisco accommodations:

  • Loews Regency San Francisco: 5-star hotel with a restaurant, a 24-hour fitness center, and bar, steps from Embarcadero Center. Our guests enjoy the hotel's comfortable rooms and central location.
  • Omni San Francisco Hotel: 4.5-star hotel with a restaurant, a fitness center, and bar, steps from TransAmerica Pyramid. Expedia travelers like this hotel's spacious rooms and central location.
  • Hyatt Regency San Francisco: 4-star hotel with a restaurant, a 24-hour fitness center, and bar, steps from Ferry Building. Our guests rate this hotel highly for its comfortable rooms and central location.

Must See in This San Francisco Neighborhood


Explore Downtown San Francisco's landmarks like Powell and Market Cable Car Turnaround, TransAmerica Pyramid, and Civic Center Plaza and learn about the local history. You could also plan a visit to San Francisco Museum of Modern Art or AT&T Park while you're in the neighborhood.

Favorite places to visit in the surrounding Downtown San Francisco area include San Francisco City Hall, San Francisco Bay, and Westfield San Francisco Centre. Exploratorium and Lombard Street are also worth a visit when you're out sightseeing in San Francisco.


Getting Around Downtown San Francisco and the Greater San Francisco Area


For a quick way to explore the city, catch a ride on metro transit at Powell St. Station, Montgomery St. Station, or Embarcadero Station. If you want to head out of town, you can hop aboard a train at San Francisco 4th and King Station.

Explore a world of travel with Expedia