Find Business Hotels in St. Charles, MO

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Pick from 17 St. Charles Business Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Lobby
Drury Plaza Hotel St. Louis St. Charles
3.0 star property
9.8 out of 10, Exceptional, (1003)
"MY experience was great! A problem came up in the room & staff stepped up with solution. I love the Drury Plaza Hotel! "
The price is $139
$159 total
includes taxes & fees
Jun 2 - Jun 3
Drury Plaza Hotel St. Louis St. Charles
Desk, laptop workspace, blackout drapes, iron/ironing board
Country Inn & Suites by Radisson, St. Charles, MO
2.5 star property
9.4 out of 10, Exceptional, (1007)
"Very nice hotel with hospitality "
The price is $135
$156 total
includes taxes & fees
Jun 2 - Jun 3
Country Inn & Suites by Radisson, St. Charles, MO
Lobby
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
8.8 out of 10, Excellent, (1193)
"It was the perfect location. We had 4 of our 6 kids with us and the staff put us in a corner suit away from others so we didnt have to constantly hush our children. The hotel was absolutely beautiful! This has been the very first hotel we have stayed in that had an open hottub since covid started and it was very nice and relaxing. We all very much enjoyed our stay and will be back. "
The price is $143
$164 total
includes taxes & fees
May 19 - May 20
Embassy Suites by Hilton St. Louis St. Charles
Property entrance
Comfort Suites St Charles - St Louis
2.5 star property
8.4 out of 10, Very Good, (656)
"Beautiful room, clean. Vrty nice room. Excellent checkin"
The price is $89
$102 total
includes taxes & fees
Jun 2 - Jun 3
Comfort Suites St Charles - St Louis
Casino
Ameristar Casino Resort and Spa
4.5 star property
8.2 out of 10, Very Good, (1002)
"Great stay and plenty to do. "
The price is $169
$208 total
includes taxes & fees
May 14 - May 15
Ameristar Casino Resort and Spa
Exterior
Hampton Inn St. Charles St. Peters
2.5 star property
8.2 out of 10, Very Good, (1004)
"Our stay was ok bed and pillows were comfortable. Breakfast needs gluten and dairy free choices. Staff were pleasant "
The price is $110
$126 total
includes taxes & fees
May 27 - May 28
Hampton Inn St. Charles St. Peters
Exterior
Holiday Inn Express Hotel and Suites St. Charles, an IHG Hotel
3.0 star property
8.2 out of 10, Very Good, (642)
"The location and service were great! Our bathroom floor wasn’t perfectly clean but we don’t usually walk around barefoot in hotels anyway."
The price is $135
$155 total
includes taxes & fees
May 12 - May 13
Holiday Inn Express Hotel and Suites St. Charles, an IHG Hotel
Pool
Super 8 by Wyndham St Charles
2.0 star property
8.0 out of 10, Very Good, (929)
"an easy and comfortable stay"
The price is $81
$93 total
includes taxes & fees
May 27 - May 28
Super 8 by Wyndham St Charles
Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, pillowtop beds, in-room safe, desk
Best Western Plus The Charles Hotel
3.0 star property
7.8 out of 10, Good, (1003)
"Good so far"
The price is $96
$111 total
includes taxes & fees
May 12 - May 13
Best Western Plus The Charles Hotel
Suite, 2 Bedrooms | Premium bedding, down comforters, pillowtop beds, in-room safe
Candlewood Suites St Louis St Charles, an IHG Hotel
2.5 star property
7.6 out of 10, Good, (638)
"Best hotel in St. Charles."
The price is $99
$114 total
includes taxes & fees
May 14 - May 15
Candlewood Suites St Louis St Charles, an IHG Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much do business-friendly hotels in St. Charles cost?
Business-friendly hotels in St. Charles range between $89 and $169 per night. This means you can reserve a stay with conveniences like conference rooms and workspaces at a price that’s within your budget. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in St. Charles?
Corporate travelers recommend Drury Plaza Hotel St. Louis St. Charles. This 3-star property offers amenities such as a swimming pool and front desk services. Best Western Plus St. Louis Airport Hotel is another popular option for a work trip. It has a 2.5-star rating and conveniences like a pillowtop mattress and an electric car charging station. You can pick from multiple business-friendly hotels in St. Charles that have a total average guest review rating of 7.6.
How many business-friendly hotels are there in St. Charles?
When your job takes you to St. Charles, you’ll have 17 business-friendly hotels to select from. These properties offer a well-suited location with the amenities corporate travelers need.
What are the best cheap business-friendly hotels in St. Charles?
Save money on your next work trip to St. Charles by choosing one of our business-friendly hotels that start from $89 per night. One low-priced property is Best Western Plus St. Louis Airport Hotel, which comes with handy amenities like a pillowtop mattress and a swimming pool. Fairfield Inn & Suites St Louis Westport is another sought-after pick for corporate travelers on a strict budget. It offers a barbecue grill and a firepit. When you’re ready to explore the sights of St. Charles, add a few terrific free attractions to your work trip itinerary. James S. McDonnell Prologue Room and Historic Main Street are visitor favorites. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in St. Charles that are also business friendly?
Vacationing with the fam, and keeping an eye on work matters, is a snap at Drury Plaza Hotel St. Louis St. Charles. Take advantage of amenities including a swimming pool and complimentary breakfast at this 3-star getaway in St. Charles. Also look up Best Western Plus St. Louis Airport Hotel. Close your meetings and then spend quality time with your loved ones at this 2.5-star pick. A swimming pool and complimentary breakfast are a couple of the conveniences available here. Naturally, there’s plenty to do in St. Charles aside from work! Take the kids to some family-friendly attractions, such as Kokomo Joes Family Fun Center and Lewis & Clark Boathouse and Nature Center.
Are there any 5-star business-friendly hotels in St. Charles?
Although there aren’t any 5-star business-friendly hotels in St. Charles, there are some 4-star options that will meet your needs. Located approximately 2 mi from the downtown area, Ameristar Casino Resort and Spa comes with concierge services and spa facilities. Another stylish property where you can get down to work is DoubleTree by Hilton St. Louis - Westport. It’s roughly 7 mi from the center of St. Charles and offers amenities like concierge services and premium bedding.
Why book your business-friendly hotel in St. Charles with Expedia?
With amenities like meeting rooms, laundry facilities and on-site cafés, our business-friendly stays come with everything you’ll need to settle your important deal — and then unwind! Enter your destination and preferred travel dates and we’ll help you plan the rest.
How can I find cheap business-friendly hotels in St. Charles?
When work takes you to St. Charles, our “business friendly” filter will help you find the ideal hotel. From fast WiFi to computer stations and concierge services, they come with the amenities you need to do your job. Another useful tip? Refine your search by your budget and preferred star rating to see the most affordable options.
What is there to do in St. Charles near my business-friendly hotel?
There are loads of superb things to see and experience in St. Charles. Make tracks to leading attractions like Kokomo Joes Family Fun Center, Historic Aircraft Restoration Museum and James S. McDonnell Prologue Room. New Jewish Theatre, Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are other must-see’s.