Search Hotels in Mississippi County

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Compare 98 hotels in Mississippi County with room rates, reviews, and availability. Most hotels are fully refundable.

Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (611)
"Staff was great! Room was nice. "
United States
Lana
$69 nightly
The price is $77
Dec 7 - Dec 8
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
$65 nightly
The price is $72
Dec 27 - Dec 28
Total with taxes and fees
Quality Inn Charleston - Sikeston
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

2.0 star property
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
United States
David
$60 nightly
The price is $67
Dec 7 - Dec 8
Total with taxes and fees
Eagle Inn Charleston
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 star property
Cairo
6.6 out of 10, (272)
"Break fast was excellent "
United States
Uma
$70 nightly
The price is $78
Dec 13 - Dec 14
Total with taxes and fees
Quality Inn Cairo I-57
Fridge, microwave, oven, stovetop
Charming 3-bedroom house near ball park in quiet neighborhood

Charming 3-bedroom house near ball park in quiet neighborhood

Bardwell
10.0 out of 10, Exceptional, (11)
"Quaint stay to see Grand and kids. "
United States
Sheila C.
$150 nightly
The price is $161
Dec 17 - Dec 18
Total with taxes and fees
Charming 3-bedroom house near ball park in quiet neighborhood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent
"Staff was great. Hotel was clean. Great sleep. "
Jeffrey 1-night trip
Posted 2 days ago
Holiday Inn Express & Suites Sikeston Southwest by IHG

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