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Find hotels in Sikeston, MO from $55

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Check Sikeston hotel prices

Tonight
May 10 - May 11
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May 11 - May 12
This weekend
May 10 - May 12

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Compare 279 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Drury Inn & Suites Sikeston, MO
Property amenity
Drury Inn & Suites Sikeston, MO
3.0 star property
9.4 out of 10, Exceptional, (1002)
"Easy access of the highway in a very safe and convenient location. Newer hotel and staff was excellent. The included dinner and breakfast was an unexpected surprise and didn’t disappoint. "
The price is $108
$123 total
includes taxes & fees
May 19 - May 20
Drury Inn & Suites Sikeston, MO
Travel Inn & Suites
Hallway
Travel Inn & Suites
2.5 star property
8.4 out of 10, Very Good, (521)
"King room was small and sink in the bathroom was very out-dated. There was no counter space. Picture shows an ottoman, but there was none."
The price is $65
$74 total
includes taxes & fees
May 12 - May 13
Travel Inn & Suites
Pear Tree Inn Sikeston
Lobby
Pear Tree Inn Sikeston
2.5 star property
9.4 out of 10, Exceptional, (1003)
"So glad I found the Pear Tree Inn. Clean room and a comfortable bed and the staff were wonderful!"
The price is $94
$108 total
includes taxes & fees
May 15 - May 16
Pear Tree Inn Sikeston
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Best Western Plus Sikeston
Free daily full breakfast
Best Western Plus Sikeston
2.5 star property
8.4 out of 10, Very Good, (1003)
"It was hard to find. No prominant sign. Otherwise ok."
The price is $101
$114 total
includes taxes & fees
May 12 - May 13
Best Western Plus Sikeston
Days Inn and Suites by Wyndham Sikeston
1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston
2.0 star property
7.0 out of 10, Good, (1002)
"The staff was very friendly but once we got to the room, there was blood on the top sheet and hair in the shower. We were only there for a quick sleep on a long road trip so I didn’t bother telling anyone. Just pulled off the comforter and slept on the sheets. "
The price is $71
$81 total
includes taxes & fees
May 27 - May 28
Days Inn and Suites by Wyndham Sikeston
Comfort Inn & Suites Sikeston I-55
Exterior
Comfort Inn & Suites Sikeston I-55
2.5 star property
8.4 out of 10, Very Good, (194)
"The best value for money I have ever had. Exceptional service and cleanliness. My room was fantastic. Huge and spotless. Theres an elevator and they are pet friendly. I travel a great deal and this was the best. Good breakfast with lots of choices, including healthy choices. Safe area right next to a McDonalds and a Burger King, but not 24hr ones so it was quiet at night. "
The price is $89
$101 total
includes taxes & fees
May 12 - May 13
Comfort Inn & Suites Sikeston I-55
Hampton Inn Sikeston
Exterior
Hampton Inn Sikeston
2.5 star property
9.0 out of 10, Wonderful, (264)
"Great place and very clean and friendly staff!"
The price is $128
$145 total
includes taxes & fees
May 19 - May 20
Hampton Inn Sikeston
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Exterior
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (340)
"Went for the eclipse and paid an outrageous price but otherwise a very nice hotel "
The price is $123
$139 total
includes taxes & fees
May 19 - May 20
Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
Super 8 by Wyndham Sikeston/Miner Area
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free cribs/infant beds
Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
6.4 out of 10, (470)
"It was by the outlet store"
The price is $60
$68 total
includes taxes & fees
May 19 - May 20
Super 8 by Wyndham Sikeston/Miner Area
Dexter Inn
Exterior
Dexter Inn
2.5 star property
7.0 out of 10, Good, (234)
"A good, not-too-busy spot to stay in the vicinity of the total eclipse track the night before."
The price is $62
$70 total
includes taxes & fees
May 17 - May 18
Dexter Inn
Econo Lodge Dexter
Desk, iron/ironing board, free WiFi, bed sheets
Econo Lodge Dexter
2.0 star property
6.6 out of 10, (184)
"Excellent staff "
The price is $62
$69 total
includes taxes & fees
May 17 - May 18
Econo Lodge Dexter
Travelodge by Wyndham Dexter
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter
2.0 star property
7.4 out of 10, Good, (320)
"Nice clean room "
The price is $93
$104 total
includes taxes & fees
May 27 - May 28
Travelodge by Wyndham Dexter
Hickory House Inn
BBQ/picnic area
Hickory House Inn
2.5 star property
5.6 out of 10, (95)
"This hotel needs major remodeling! I probably wouldn’t stay there again. We traveled to watch theTotal Solar Eclipse in Dexter, MO. It was the cheapest place to stay in the area at the time. I would not recommend this place. "
The price is $55
$62 total
includes taxes & fees
May 11 - May 12
Hickory House Inn
Country Yard Inn and Suite
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite
2.0 star property
7.4 out of 10, Good, (31)
"Considering the price of the room, it was adequate. Thankfully it was a cooler weekend (the previous week had been uncharacteristically warm) or we would have had to move rooms due to an inadequate air conditioning unit. That being said, it was a clean room and the bed was comfortable. The motel is convenient to the interstate and the main road into Sikeston. Our room was at the far end of the motel, so away from any interstate noise."
The price is $60
$69 total
includes taxes & fees
Jun 8 - Jun 9
Country Yard Inn and Suite
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
Smart TV, fireplace, stereo
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
8.6 out of 10, Excellent, (15)
"The old house was charming. It could benefit from a really good, deep clean. The bathrooms and beds/linens were very clean and the kitchen was functional. We didn't use the outdoor area but it was nice and well suited to a comfortable place to hang out on a nice day. The town has food and necessity shopping available and easily accessible. Overall we were pleased with our overnight stay. "
The price is $89
$195 total
includes taxes & fees
May 16 - May 17
Dexter Homestead. VERY Cozy & Clean 7 Bed home.
Modern and Cozy Apartment with large windows and sunlight.
Private kitchen
Modern and Cozy Apartment with large windows and sunlight.
Modern and Cozy Apartment with large windows and sunlight.
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See all available properties in Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Where is the best place to stay in Sikeston?

Drury Inn & Suites Sikeston, MO is ranked highly by Expedia customers. This hotel offers free breakfast and an outdoor pool. Other top choices based on reviews include Pear Tree Inn Sikeston and Hampton Inn Sikeston. See all available top hotels, or vacation rentals in Sikeston.

What are some of the best vacation rentals in Sikeston?

Notting Hill Cottage: This vacation home rental outside of Sikeston offers a patio, a private yard, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. You and your friends and family can relax into your vacation with amenities like a spa tub. See all vacation rentals in Sikeston.

If I need to cancel my hotel reservation in Sikeston, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.

Where can I learn more about changing or cancelling my trip to Sikeston?

For more details about changing or cancelling your trip to Sikeston, head over to our customer service page.

What's the best budget-friendly hotel in Sikeston?

Based on reviews, Travel Inn & Suites is a popular hotel for our travelers who want a more economical choice, and features free breakfast and free WiFi. View all budget hotels in Sikeston.

What's the best hotel for a family vacation in Sikeston?

Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids. Kids of all ages will also enjoy a visit to The Book Bug. Find more child-friendly accommodations in Sikeston.

What is the top LGBTQ-friendly hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Sikeston.

What's the best pet-friendly accommodation in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel for people traveling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good options for you and your pet's trip include Pear Tree Inn Sikeston and Days Inn and Suites by Wyndham Sikeston. See more pet-friendly hotel accommodations in Sikeston.

Where is the best hotel to stay close to Central Park?

Hampton Inn Sikeston is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 1 mi (1.6 km) from Central Park. Another good option is Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel, located just 0.9 mi (1.5 km) away.

What about the best place to stay close to Sikeston Depot Museum?

One of the top choices for your stay is Pear Tree Inn Sikeston, located 3.1 mi (5 km) from Sikeston Depot Museum, and this hotel offers free breakfast and an outdoor pool. Hampton Inn Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel are two other good options within a few miles.

What's the best hotel for a golf vacation in Sikeston?

Travel Inn & Suites is a hotel featuring free breakfast and free WiFi, and it's a top choice for playing a round of golf. You can tee off at Boot Heel Golf Club during your trip. See more golf hotels in Sikeston.

What are some accommodations with pools in Sikeston?

Drury Inn & Suites Sikeston, MO is a top hotel with an indoor pool, an outdoor pool, and free buffet breakfast. Other choices with an onsite pool include Best Western Plus Sikeston and Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel. View all hotels with pools in Sikeston.

What is the best spa hotel in Sikeston?

Drury Inn & Suites Sikeston, MO is a top spa hotel featuring a pool and a fitness center. See all spa hotels in Sikeston.

What's the best place to stay near Barkley Regional Airport (PAH)?

Drury Inn & Suites Paducah is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and an indoor pool. It's located 4.7 mi (7.6 km) from Barkley Regional Airport. Other choices close to the airport include La Quinta Inn & Suites by Wyndham Paducah and Baymont by Wyndham Paducah.

What is staying in Sikeston like?

Families will find kid-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 13 hotels and other accommodations to choose from. Find out more about Sikeston.

What are the top places to visit in Sikeston?

Favorite places to visit include The Book Bug, Sikeston Depot Museum, and Central Park. Additionally, you might want to add Boot Heel Golf Club to your itinerary. Check out what more to see and do in Expedia's Sikeston guide.

What's the seasonal weather like in Sikeston?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Sikeston is 60 inches.