Search Hotels in Mississippi County

Top Cities in Mississippi County

Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky.
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Charleston

Charleston
Bridge over Mississippi River, New Orleans in background
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East Prairie

East Prairie

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Our top choices for Mississippi County hotels

Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (622 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
$62 nightly
The price is $69
Feb 2 - Feb 3
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
Front of property

The Riverstone Hotel

The Riverstone Hotel
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
$70 nightly
The price is $78
Feb 2 - Feb 3
Total with taxes and fees
The Riverstone Hotel
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
"Middle of nowhere hotel was ok"
United States
David
$64 nightly
The price is $71
Feb 2 - Feb 3
Total with taxes and fees
Eagle Inn Charleston
Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (276 reviews)
"The quality was not what I expected for a "Quality Inn". It felt more light a Motel 6. I was not satisfied at all."
United States
ReShena
$73 nightly
The price is $81
Mar 1 - Mar 2
Total with taxes and fees
Quality Inn Cairo I-57
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mississippi County Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value. "
Georgine 1-night trip
Posted 19 hours ago
Drury Inn & Suites Sikeston, MO

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