Search Hotels in New Madrid County
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member Prices
Be pickySearch almost a million properties worldwide
Top Cities in New Madrid County
Sikeston
New Madrid
Check prices for these dates
Our top choices for New Madrid County hotels
1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,007 reviews)
"Nice hotel with evening dinner and buffet breakfast."
Sally
$109 nightly
The price is $125
Aug 10 - Aug 11
Total with taxes and fees
2. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,005 reviews)
"The hotel looked very good from the outside. And when you first went into the lobby was very nice. But the rooms were very basic. They was absolutely no pictures hung from the walls. The kitchen area just had a small refrigerator and a microwave setting on top of it. I had to ask for a coffee maker, and it was a single cup coffee maker. The free breakfast was very minimal. But at least everything was clean."
Robert S
$68 nightly
The price is $78
Aug 9 - Aug 10
Total with taxes and fees
3. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very Good, (1,006 reviews)
"Old but well maintained for quick overnight stay"
Carl
$93 nightly
The price is $106
Aug 9 - Aug 10
Total with taxes and fees
4. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (594 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
Brandi
$103 nightly
The price is $116
Aug 23 - Aug 24
Total with taxes and fees
5. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (804 reviews)
"I love it there."
Sharika West
$62 nightly
The price is $71
Jul 29 - Jul 30
Total with taxes and fees
6. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (486 reviews)
"Nice!"
theresa
$87 nightly
The price is $98
Aug 23 - Aug 24
Total with taxes and fees
7. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (101 reviews)
"Perfect last minute stop on our road trip
Very clean, well maintained and pleasant staff"
Dwain
$110 nightly
The price is $125
Aug 9 - Aug 10
Total with taxes and fees
8. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
7.0 out of 10, Good, (658 reviews)
"Staff is great rooms clean no bugs and bed was comfortable "
James
$63 nightly
The price is $72
Aug 9 - Aug 10
Total with taxes and fees
9. Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (147 reviews)
"Great clean place to stay at"
William
$59 nightly
The price is $67
Jul 29 - Jul 30
Total with taxes and fees
10. Travel Inn Marston I-55 by Hotel O
Travel Inn Marston I-55 by Hotel OMarston
6.0 out of 10, (127 reviews)
"OLD FACILITY, NEED TO FIX SOMETHINGS."
Bosup
$76 nightly
The price is $86
Jul 29 - Jul 30
Total with taxes and fees
11. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (18 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
Jason
$109 nightly
The price is $123
Aug 16 - Aug 17
Total with taxes and fees
12. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very Good, (301 reviews)
"Hotel was nice an clean. Friendly staff. Clean hotel rooms and free breakfast every morning."
Starlette
$87 nightly
The price is $100
Aug 21 - Aug 22
Total with taxes and fees
13. Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very Good, (69 reviews)
"Clean room, The receptionist very friendly, good parking."
Temera
$74 nightly
The price is $84
Jul 29 - Jul 30
Total with taxes and fees
14. OYO Malden Airport Inn
OYO Malden Airport InnMalden
6.4 out of 10, (78 reviews)
"Clean room, cleaning staff friendly, AC working, overflowing dumpster."
James
$59 nightly
The price is $63
Aug 2 - Aug 3
Total with taxes and fees
15. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
Jessica S.
$343 nightly
The price is $369
Aug 1 - Aug 2
Total with taxes and fees
16. King Bed|Non-Smoking
King Bed|Non-SmokingMalden MO
$89 nightly
The price is $98
Aug 2 - Aug 3
Total with taxes and fees
17. 2 Queen Beds|Non-Smoking
2 Queen Beds|Non-SmokingMalden MO
$99 nightly
The price is $108
Aug 2 - Aug 3
Total with taxes and fees
18. Cozy 2-bedroom cottage in Sikeston’s historic north end. 2 min drive to hospital
Cozy 2-bedroom cottage in Sikeston’s historic north end. 2 min drive to hospitalSikeston
19. Tranquil 2-bedroom apartment with AC in charming Sikeston Missouri
Tranquil 2-bedroom apartment with AC in charming Sikeston MissouriSikeston
20. King Bed | Non-Smoking
King Bed | Non-SmokingMarston MO
$96 nightly
The price is $96
Jul 31 - Aug 1
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top New Madrid County Hotel Reviews
Hampton Inn By Hilton Dexter
10/10 Excellent
Explore a world of travel with Expedia
- Motels in Portageville
- Rv Parks in New Madrid County
- Poplar Bluff Hotels
- Bragg City Hotels
- Rv Parks in New Madrid
- Cheap Hotels in Sikeston
- Apartments in Parma
- Motels in Lilbourn
- Matthews Hotels
- Charleston Hotels
- 2 Star Hotels in Marston
- Hotels near Malden Regional
- Hayti Hotels
- Cabin Rentals in Sikeston
- Pet-Friendly Hotels in Sikeston
- Portageville Hotels
- 3 Star Hotels in Parma
- Rv Parks in Morehouse
- Malden Hotels
- Motels in Parma
- 5 Star Hotels in Malden
- Miner Hotels
- Hotels near Hunter-Dawson State Historic Site
- Hotels with an Indoor Pool in Sikeston
- East Prairie Hotels
- Marston Hotels
- Bernie Hotels
- Pet-Friendly Hotels in Marston
- Risco Hotels
- Bloomfield Hotels
- Gideon Hotels
- 2 Star Hotels in North Lilbourn
- Kennett Hotels
- 5 Star Hotels in New Madrid
- Canalou Hotels
- Cabin Rentals in New Madrid
- 4 Star Hotels in Marston
- Homestown Hotels
- Motels in Malden
- Motels in Matthews
- Hotels near Big Oak Tree State Park
- Cabin Rentals in New Madrid County
- Cottages in New Madrid
- Cape Girardeau Hotels
- Hotels near River Ridge Winery
- Dexter Hotels
- Bertrand Hotels
- New Madrid Hotels
- Motels in New Madrid
- Hotels near Black Island Conservation Area
- Caruthersville Hotels
- Campbell Hotels
- Cabin Rentals in Portageville
- Hotels near Century Casino Caruthersville
- Sikeston Hotels
- Flights from Tallapoosa
- Flights from Malden Regional
- Flights to Portageville
- Flights from Malden
- Flights to Sikeston
- Flights from Morehouse
- Flights from North Lilbourn
- Flights from Lilbourn
- Flights from Risco
- Flights to Malden
- Flights from Cape Girardeau Municipal
- Flights to New Madrid
- Flights from Sikeston Memorial Municipal
- Flights from Parma
- Flights from New Madrid
- Flights to Catron
- Flights to New Madrid County
- Flights from Baker
