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Search Hotels in Cape Girardeau County

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Cape Girardeau

Cape Girardeau

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Dec 6 - Dec 7
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Dec 7 - Dec 8
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Dec 12 - Dec 14
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Dec 19 - Dec 21

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Compare 248 hotels in Cape Girardeau County with room rates, reviews, and availability. Most hotels are fully refundable.

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1000)
"Great place and staff, very accommodating!"
United States
Megan
$90 nightly
The price is $102
Dec 11 - Dec 12
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby sitting area
The Riverview

The Riverview

4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (464)
"Place was nice and safe"
United States
ryan
$93 nightly
The price is $105
Dec 8 - Dec 9
Total with taxes and fees
The Riverview
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (659)
"Great place "
United States
GUY
$78 nightly
The price is $85
Jan 4 - Jan 5, 2026
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
$83 nightly
The price is $88
Dec 8 - Dec 9
Total with taxes and fees
Drury Inn & Suites Jackson MO
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Great stay"
United States
Heather
$70 nightly
The price is $79
Dec 11 - Dec 12
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.0 out of 10, Very Good, (876)
"Clean room, low noise and very comfortable!"
United States
Richard
$70 nightly
The price is $84
Dec 14 - Dec 15
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"Nice place for a stay at a reasonable price."
United States
Arthur
$70 nightly
The price is $79
Dec 11 - Dec 12
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (98)
"It was a nice stay"
United States
Douglas
$87 nightly
The price is $99
Dec 14 - Dec 15
Total with taxes and fees
Tru By Hilton Cape Girardeau
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"I do love this hotel chain. Another great visit!"
United States
Mark
$90 nightly
The price is $102
Dec 11 - Dec 12
Total with taxes and fees
Drury Inn & Suites Cape Girardeau
Lobby
Quality Inn

Quality Inn

2.5 star property
Cape Girardeau
7.2 out of 10, Good, (680)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
$60 nightly
The price is $68
Jan 4 - Jan 5, 2026
Total with taxes and fees
Quality Inn
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
$95 nightly
The price is $107
Dec 22 - Dec 23
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (781)
"Excellent stay"
United States
Christina
$99 nightly
The price is $112
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (466)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
$116 nightly
The price is $131
Dec 21 - Dec 22
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
$88 nightly
The price is $99
Dec 14 - Dec 15
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau
Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets
Town House Inn

Town House Inn

2.5 star property
Jackson
7.6 out of 10, Good, (422)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
$68 nightly
The price is $74
Dec 14 - Dec 15
Total with taxes and fees
Town House Inn
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
$57 nightly
The price is $64
Jan 4 - Jan 5, 2026
Total with taxes and fees
Town House Inn Cape Giradreau
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
Jackson
8.2 out of 10, Very Good, (739)
"Dirty "
United States
Jon
$80 nightly
The price is $86
Dec 28 - Dec 29
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
$150 nightly
The price is $170
Dec 7 - Dec 8
Total with taxes and fees
Rockwood Inn
Interior
Little Blue Cottage on Spanish

Little Blue Cottage on Spanish

Cape Girardeau
8.6 out of 10, Excellent, (48)
"Some issues with check-in. Very nice area. Lot of history."
United States
Jeffrey M.
$101 nightly
The price is $101
Dec 7 - Dec 8
Total with taxes and fees
Little Blue Cottage on Spanish
Exterior
La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau

2.0 star property
Jackson
9.4 out of 10, Exceptional, (3)
"Nice place "
United States
jermaine
La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Cape Girardeau County, MO

Showing deals for:Dec 19 - Dec 21

Image gallery for The Riverview

Lobby sitting area

The Riverview

4.0 star property
Cape Girardeau
9.4/10Exceptional (464 reviews)
15% off
$180 nightly
Price is $407
Total with taxes and fees
The Riverview
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Top Cape Girardeau County Hotel Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
Brian 1-night trip
Posted 4 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Price trends for hotels in Cape Girardeau County

Less expensive
More expensive
This month
Next month
December
July
$75
$82
Month
Price
January
$82
February
$84
March
$86
April
$98
May
$98
June
$101
July
$102
August
$97
September
$97
October
$101
November
$96
December
$75
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Cape Girardeau County. Select dates and complete search for nightly totals inclusive of taxes and fees.

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